Protein Alignment CG7747 and cyp8

DIOPT Version :10

• Sequence 1: NP_611113.1
• Gene: CG7747 / 36820
• FlyBaseID: FBgn0034109
• Length: 517
• Species: Drosophila melanogaster
• Sequence 2: NP_594502.2
• Gene: cyp8 / 2541969
• PomBaseID: SPAC21E11.05C
• Length: 516
• Species: Schizosaccharomyces pombe
• Alignment Length: 547
• Identity: 216/547 - (39%)
• Similarity: 309/547 - (56%)
• Gaps: 61/547 - (11%)

  Fly     1 MGKRQHQKDKMYLTYTEWSEL---YGGKKVESLENDHVKFKRLPFEHCCITMAPYEMPYC----D 58
            |||   ..||:|:|.||.|.:   :||....:.:|....:|:|||.:|.:::.|:..|.|    .
pombe     1 MGK---NTDKLYITQTEHSGVHGWHGGMSGIAQKNSTTSYKQLPFNYCSLSLQPFNHPCCLVDET 62

  Fly    59 LQGNVFEYEAILKFLKTFKVNPITGQKMDSKSLVKLNFHRNANDEYHCPALFKPFSKNSHIVAVA 123
            .|..:|::..|:.:|:....|||.|||.....|:||.|.:|:.:||..|...|.|::.|||||:.
pombe    63 KQAIIFDFRFIVPWLRKHGTNPINGQKASMSDLIKLKFAKNSAEEYCDPVTMKSFTRFSHIVAIR 127

  Fly   124 TTGNVYCWEAIDQLNIKTKNWKDLVDDTPFQRKDIITIQDPQKLEKYDISTFYHIKKNLR--VLT 186
            :|||.:.|:.|::||||.|:|:|||::..|.|.||||||||..:|..|.|.....|:..|  .:|
pombe   128 STGNCFSWDTIERLNIKPKHWRDLVNEEQFTRDDIITIQDPHNVENRDFSAIQKQKETARDEKIT 192

  Fly   187 EEEQQERKNPASGRIKTMNLETKETLEQLQQDYQPAEEEASTSKRTAD--KFNAAHYSTGAVAAS 249
            :.:...:.:.|.....|.:.|...:|:              :||..|.  ..:.|.::||..|||
pombe   193 KAKIALQASRAKSTESTSSPELSHSLD--------------SSKSIASDMPIHRASHTTGYAAAS 243

  Fly   250 FTSTAMVPVSQIEAAII--DDDLVKYERVKKKGYVRLNTNLGPLNLELFCDQTPRACDNFIKHCA 312
            .|||:..||::.|.|||  :|.::.:.|:|.|||.|:.||.|.:|:||..|..|.|..||::...
pombe   244 LTSTSFTPVTKNERAIIAEEDYMLNHTRIKHKGYARIVTNHGEINIELHTDYAPHAVYNFVQLAK 308

  Fly   313 NGYYNNVMFHRSIRNFIVQGGDPTGSGSGGESIWGKKFEDEFKPNLTHTGRGVLSMANSGPNTNG 377
            .|||.|.:|||:|..|::|||||:|:|.||:|||||.|:|||...|.|..||::||||.|.||||
pombe   309 QGYYRNTIFHRNIARFMIQGGDPSGTGRGGQSIWGKPFKDEFCNPLKHDDRGIISMANRGKNTNG 373

  Fly   378 SQFFITYRSCKHLDGKHTIFGKLVGGLDTLQKMENIEVDNKDRP-----IEDIIIESSQVFVNPF 437
            |||||.|...||||.||||||::||||:.|..:|.:..::.|.|     :|||||     ||:||
pombe   374 SQFFILYGPAKHLDNKHTIFGRVVGGLNVLDALEKVPTNSNDHPKLPIKLEDIII-----FVDPF 433

  Fly   438 AEAAEQLAKEREEEAAGKEEIVKKEEQQKRMKEPLKVYRE------------GVGKYLKLQTVAK 490
            .|..:.   |||:|...::|    ||::..:.......|:            .||||||.:...:
pombe   434 EEWKKD---EREKEKRKRQE----EEEENNLDRTSWTGRDLSASSTDHSLNASVGKYLKKEVSLE 491

  Fly   491 KPEAPLTSAQAAKKKKLANGFGDFSSW 517
              |...||....||||...|||:|.:|
pombe   492 --EKTFTSTVNPKKKKARTGFGNFDAW 516

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING-Ubox_PPIL2	41..113	CDD:438325	25/75 (33%)
		RING_Ubox	104..162	CDD:473075	29/57 (51%)
		cyclophilin_RING	281..439	CDD:238904	86/162 (53%)
cyp8	NP_594502.2	RING-Ubox_PPIL2	41..117	CDD:438325	25/75 (33%)
		RING_Ubox	108..166	CDD:473075	29/57 (51%)
		cyclophilin_RING	277..433	CDD:238904	84/160 (53%)