DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7747 and ppwd1

DIOPT Version :9

Sequence 1:	NP_611113.1	Gene:	CG7747 / 36820	FlyBaseID:	FBgn0034109	Length:	517	Species:	Drosophila melanogaster
Sequence 2:	XP_002934239.3	Gene:	ppwd1 / 100488042	XenbaseID:	XB-GENE-1001509	Length:	640	Species:	Xenopus tropicalis

Alignment Length:	363	Identity:	107/363 - (29%)
Similarity:	164/363 - (45%)	Gaps:	92/363 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    84 QKMDSKSLVKLNFHRNANDEYHCPALFKPFSKNSHIVAVATTGNVYCWEAIDQLNIKTKNWKDLV 148
            :|:|:..|:.:.|     ||            ..|.|...|      ...|..:|::|
Frog   345 EKVDAMKLMNIIF-----DE------------TGHFVLYGT------MLGIKVINVET------- 379

  Fly   149 DDTPFQRKDIITIQDPQKLEKYDISTFYHIKKNLRVLTEEEQQERKNPASGRIKTMNLETKETLE 213
                  .:.:..:...:.:....::.|..:.|..|..|..|.:...||              .|.
Frog   380 ------NRCVRILGKQENIRAMQLAVFQGVAKKHRAATTVEMKASDNP--------------VLL 424

  Fly   214 QLQQD------------------YQPAEEEASTSKRTADKFNAAHYSTGAVAASFTSTAMVPVSQ 260
            .:|.|                  .:|.:.:::.|.|  |.||........:||          :|
Frog   425 AVQPDPTIVCTAFKKNRFYVFTKREPEDTKSAESDR--DVFNEKPSKEEVMAA----------TQ 477

  Fly   261 IEAAIIDDDLVKYERVKKKGYVRLNTNLGPLNLELFCDQTPRACDNFIKHCANGYYNNVMFHRSI 325
            .|.:         :||.....:  :|::|.::::||..:.|:..:||..|..|||||..||||.|
Frog   478 AEGS---------KRVSDSAII--HTSMGDIHVKLFPVECPKTVENFCVHSRNGYYNRHMFHRVI 531

  Fly   326 RNFIVQGGDPTGSGSGGESIWGKKFEDEFKPNLTHTGRGVLSMANSGPNTNGSQFFITYRSCKHL 390
            :.|::|.|||||:|.|||||||.:|||||...|.|.....|||||:||:|||||||:|......|
Frog   532 KGFMIQTGDPTGTGMGGESIWGGEFEDEFHATLRHDRPYTLSMANAGPSTNGSQFFLTVVPTPWL 596

  Fly   391 DGKHTIFGKLVGGLDTLQKMENIEVDNK-DRPIEDIII 427
            |.|||:||::..|::.:|::.|.:|:.| |:|.|||.|
Frog   597 DNKHTVFGRVTKGMEVVQRICNSKVNPKTDKPYEDISI 634

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7747	NP_611113.1	RING	25..238	CDD:302633	27/171 (16%)
CG7747	NP_611113.1	cyclophilin_RING	281..439	CDD:238904	73/148 (49%)
ppwd1	XP_002934239.3	WD40	83..312	CDD:421866
		WD40 repeat	88..125	CDD:293791
		WD40 repeat	131..169	CDD:293791
		WD40 repeat	177..213	CDD:293791
		WD40 repeat	221..266	CDD:293791
		cyclophilin_WD40	489..637	CDD:238908	73/148 (49%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1392223at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920