Protein Alignment CG9068 and Dnah7a

DIOPT Version :10

• Sequence 1: NP_611111.1
• Gene: CG9068 / 36817
• FlyBaseID: FBgn0034106
• Length: 1227
• Species: Drosophila melanogaster
• Sequence 2: XP_006496242.1
• Gene: Dnah7a / 627872
• MGIID: 2685838
• Length: 4046
• Species: Mus musculus
• Alignment Length: 1189
• Identity: 203/1189 - (17%)
• Similarity: 412/1189 - (34%)
• Gaps: 368/1189 - (30%)

  Fly   214 SLEGIALYWTTQIRT----LLADDTLTVPHDLVTVRDEFEFWEY------RYEVLQGIND----- 263
            ||.|:...|.....:    :..::.:..|:   ||::|..|.||      :.::|..|:|
Mouse    46 SLTGVKPQWQQTAPSFHLNIKQENPVLEPY---TVKNEQSFAEYMEHCQKKGKLLDQIDDDRSAP 107

  Fly   264 QLAHSDVQKVLLLLHNAQS---------VHMPQMDGLIERARKELHKSLSNIKYLHLLIE----- 314
            ..:.|.|:.......|.:|         :..||      :.|:.|..:|:.:     :::
Mouse   108 STSRSKVKSPHKERENFKSTLPSIYRSKIKSPQ------KERENLRSTLAKV-----IMQKDGGL 161

  Fly   315 PCSKIDAATSPADLT----KLLPRIIHLIR------------FIWLNSEYYNTTRLIAALFRNLS 363
            ....||.:..|.:.|    |.:.|..:.||            ..||.    :..:|:....:.|:
Mouse   162 ESDVIDESGIPKETTSATEKDISRYYYYIRQGLDTDHVAPMEDSWLE----HVLQLVPEHLKVLT 222

  Fly   364 NQIIRFCTKQTKVEEILSGKPRFGIRICNVAIECCLTYRGIYDTISRDLAQKH-----TQMPWEL 423
            |. |:..:.:.:.:.:||.|                  :.|.|.:.:|..:|.     |::|...
Mouse   223 NS-IKVLSDEIREDYLLSVK------------------KSIVDFVLKDPREKDDDGKITELPPHR 268

  Fly   424 DE----------------GLIFNHIDAFVERLNDVIDICESMIVFGRLDENGSIPKPVFGGTCGE 472
            .|                ..|.:|::|....:..|:|:..|.....||.:.             |
Mouse   269 AEMEVLPKPWRRSFLSACSYIRDHLNAMNPMMLAVLDLWHSTFKKLRLVDI-------------E 320

  Fly   473 ELEKIAESVEV-QFLDTLNKLQQNSQAYILNVHRADWYADVAGF------------RKNMQKLEE 524
            |.....:::|: :|.:.:.|..::::..:|..    |:.:|...            .|:..||:.
Mouse   321 EFHSCQDALELSEFQNIVIKHMESAKETLLKT----WFPEVQNIFNQGNKKKQLPTGKSTAKLDS 381

  Fly   525 -----------TVQRLIFNVFQQVSN-VEEMLEALQAMLFYSYRQRGTLRK----------TYLK 567
                       .:|.||....|..:: :.:.||:::......:..|..|.|          .|:.
Mouse   382 FFNCAATLMTLQLQDLILVSMQDFTDLIAQPLESIRVFEHPGFIMRLVLDKEAIKFEPEFNEYID 446

  Fly   568 ETSKLWRMFSKEMDATSRKLLEEQSRESWLSKHVSIALGYRINLERLTWLRDRLKNSEWLPAVKE 632
            ....::.:..|.:....|  :|.:....|.||.....|...|..|.:...:::::.    ..::|
Mouse   447 SLINIYEIMIKAVSFVPR--VETKLYSQWESKSKPTTLKPIILNEIIDTHKEKIRE----VILRE 505

  Fly   633 SSPALAKFDALRHEFQKEIRLAYDDWVAKCCGFSGDLCQRLDRYLVVRSKKFKGLLECNIDASVL 697
            |   :|..:.|:         .||.:                ::|:.      |..|.:||..:.
Mouse   506 S---VAPTEHLK---------MYDKY----------------QFLIT------GKAERDIDELLF 536

  Fly   698 E------LCEQAQHFERMGFAIPSTMKK-----LYERY--DTIRSLYNG--------IIKLALSH 741
            :      |.|:.:.::::|..|..|.:|     ::|.:  :.||||...        |.|:...|
Mouse   537 QNQNYERLIEEIRKYQKLGEEIQYTSQKTVCLGMFEMHCEELIRSLVKRADVICGKLIAKMFRDH 601

  Fly   742 NRILAVLSDR-----ERKLFRPLIQACDRQLAPGVFKITYGSEFNEEFFEDGTEFIAEFQELVLI 801
            ..:..:|.|.     |:.|..||..|...::...|.|:            :.|:.:...|.||
Mouse   602 QEVNTMLCDEFEKIAEKALSTPLNTAELMEMKAHVQKL------------ETTDMLELGQRLV-- 652

  Fly   802 FKRANRGVARICEKICGTCLLHFAFSGSVDI----SVFQQQLSSRLSSSGDILRSYYSHVVELLS 862
                       ..|||...|:........||    ||||..  .|:....|..|.......||..
Mouse   653 -----------DSKICLAFLIECVNFSPADIRLNKSVFQWY--GRMGEIFDEHRKIIKEKTELYQ 704

  Fly   863 AFSGQFQSVDDEMSAEWIAYVNDMDDMLASSLMTSARGSLNKLYEALHCDADMASAPIIVVESDV 927
            .|          :......:|.:::             |..|..|..|...|:......:.::.|
Mouse   705 EF----------LKFRCERFVEELE-------------SYAKQVEEFHAFGDLLDVQRYLQKAQV 746

  Fly   928 KDGRIVFTPDMDAIGDMIN---------GIVDS-------IRSMLDQFPRLGYKLKLPKKQQRQG 976
            .:|:      :||..|.|:         |.|.|       |:..|:.:..| |:..:....:.:|
Mouse   747 LNGK------LDAAADKIDQFNAEEEAFGWVPSAYPQRKKIQDALNPYLHL-YETAVEFSTKHRG 804

  Fly   977 FAS----VFREDQECSELMRSIQAEIGIQREELAKYESEWNKN-RVLWQTTE-----EEFRQRLM 1031
            :..    ....||        ::|::|.....|.|.|..::.: ..|..|.:     |||:|.:
Mouse   805 WTEGPYHKVNPDQ--------VEADVGNYWRGLYKLEKVFHDSPNALAMTKKVHSMVEEFKQYI- 860

  Fly  1032 SKSRTAGVF-EGGI--EHYSALA-----------DDVIFE----------DAITNVYFILINQNA 1072
               ....|| ..|:  .|:.|::           |..:|.          |...::......:.:
Mouse   861 ---PLIQVFCNPGLRPRHWEAMSTIVGYPLQPSDDSTVFSFIDMNLEPFLDRFGSISEAASKEYS 922

  Fly  1073 LKSTMLDWIEKWQALNIKML--LDHGSNLMGAVYRYMRRNERNVMKVPRTIRETVAAKQLFEKLL 1135
            |:..|...:.:|.::...:|  .:.|:.::.:|.......:.:::|. :|:|.:...|. :||.:
Mouse   923 LEKAMDKMMTEWDSMEFVILPYRESGTYILSSVDDIQMLLDDHIIKT-QTMRGSPFIKP-YEKQM 985

  Fly  1136 KDVPVKQSAFTPMLELFVLLHKYQVKLSEETFEQVMGLETAWLHYLQVLEEADEMLDNEDSEAKL 1200
            ::...|                  :.|.:|..::.:.::..|| ||:.:..:.:::.....|.:.
Mouse   986 REWEGK------------------LLLLQEILDEWLKVQATWL-YLEPIFSSRDIMSQMPEEGRR 1031

  Fly  1201 LLAKHGEKFKLILKDFLED 1219
            ..|. .:.::.::|..::|
Mouse  1032 FTAV-DKTWRDVMKTVVQD 1049

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9068	NP_611111.1	DHC_N1	212..784	CDD:462457	119/696 (17%)
Dnah7a	XP_006496242.1	DHC_N2	779..1184	CDD:462462	49/306 (16%)
		DYN1	894..3688	CDD:227570	25/178 (14%)
		AAA_6	1312..1638	CDD:463697
		AAA_8	2333..2595	CDD:463701
		AAA_9	2983..3204	CDD:463702
		Dynein_C	3742..4042	CDD:465677