Protein Alignment CG9068 and Dnah3

DIOPT Version :10

• Sequence 1: NP_611111.1
• Gene: CG9068 / 36817
• FlyBaseID: FBgn0034106
• Length: 1227
• Species: Drosophila melanogaster
• Sequence 2: NP_647937.2
• Gene: Dnah3 / 38586
• FlyBaseID: FBgn0035581
• Length: 4385
• Species: Drosophila melanogaster
• Alignment Length: 1411
• Identity: 251/1411 - (17%)
• Similarity: 474/1411 - (33%)
• Gaps: 466/1411 - (33%)

  Fly   128 DEINFGTLTSDVDGCLMELLD----RLYVPFFRNYLEWNATVRNRFCS----------SMDRF-- 176
            ||::..:.|..:.|.|.|:||    ||.|  .|:.||  ..:|.|...          :||.|
  Fly   970 DELHLNSRTFILPGELEEVLDLSAARLAV--VRDNLE--LALRERRMEFEKLLAQEKRTMDGFRI 1030

  Fly   177 -----LAFLSGMHHQISGMSVMYVPFVIKEL------------------TAGPVDRYLVGSLEGI 218
                 :..|..:..::..:.:::.  .|:.|                  :|.|:...::..:|.|
  Fly  1031 REIRDVLTLEELKERVDTVDLLFT--TIENLSREAKAINTEETLLQIDVSAFPLLAEIIEKMEPI 1093

  Fly   219 ALYWTTQIRTLLADDTLTVPHDLVTVRDEFE----FWEY-RYEVL--QGINDQLAHSDVQKVLLL 276
            ...|.|..                    |||    .|.: |:|.|  .|:.:|:  .::.|::..
  Fly  1094 EKLWKTSY--------------------EFEKDYLIWMFERFECLNADGVREQV--ENMHKIMYK 1136

  Fly   277 LHNAQSVHMPQMDGLIERARKELHKSLSNIK-YLHLLIEPC-----------------SKIDAAT 323
            | :.|..:.|    :.:||.:::...:...: ||.:|...|                 .|::...
  Fly  1137 L-SRQLAYNP----VAKRAAEQMRMKIEKFRVYLPVLDSICRHGLEKRHWDQISKILGRKVNPKL 1196

  Fly   324 SP-------ADLTKLLPRIIHLIRFIWLNSEYYNTTRLIAALFRNLSNQIIRFCTKQTKVEEILS 381
            .|       .|:..:||::..:........:..|..|::.|.:|::..:::::....|.:...|.
  Fly  1197 FPTLKDMIDVDIMSILPQLEEIANAAGKEYDLNNGLRIMQADWRDVMFEVLQYRDSDTHILASLD 1261

  Fly   382 GKPRFGIRICNVAIECCLTYRGIYDTISRDLAQKHTQM---------PWELDEGLIFNHIDA--- 434
            .            |:..|.     |.|.|..|.|.:..         .||....||.|.|||
  Fly  1262 D------------IQTLLD-----DHIMRTQAMKRSPFITALGSKADDWEARLLLIQNIIDAWTQ 1309

  Fly   435 ------FVERLNDVIDICESMIVFGR-----------LDENGSIPKPVFGGT-CGEELEKIAESV 481
                  ::|.:....||...|.:.||           :.::....:.|...| ..|.||...:::
  Fly  1310 VQITWMYLEPIFSSEDIMRQMPLEGRNFKAVDKLWRKIMKHTLKDRHVMAATEYPEMLEVFTKAI 1374

  Fly   482 EVQFLDTLNK------------------LQQNSQAYILNVHRADWYADVAGFRKNMQKLEETVQR 528
            |  .|:|:.|                  |..:....||:..:     |....:.:::|..|.:..
  Fly  1375 E--DLETVTKGLNTYLEQKRLFFARFFFLSNDELLEILSETK-----DPMRVQPHLRKCFEGIGS 1432

  Fly   529 LIFN----VFQQVSNVEEMLEALQAMLFYSYRQRGTLRKTYLKETSKLWRMFSKEMDATSRKLLE 589
            |.|:    :.:.||:.||.:              ..:||...:..:.|..|:.||::......::
  Fly  1433 LTFDDNMEIVEMVSDEEERV--------------ALVRKINPQLANGLVEMWLKEVEMVMLDSVK 1483

  Fly   590 EQSRESWLSKHVSIALGYRINLERLTW--------------------LRDRLKNSEWLPA-VKES 633
            ||.||:|..        |.: :||::|                    :.:.::..| ||| :::|
  Fly  1484 EQMREAWED--------YAM-VERISWVVSWPGQVVQGISCMAWTYEVEEAIETKE-LPAYLEKS 1538

  Fly   634 SPALAKF-DALRHEFQKEIRLAYDDWVAKCCGFSGDLCQRLDRYLVVRSKKFKGLLECNIDASVL 697
            :..:|.. ..:|.:.|..:|:|.:..:         :....||.:|      |.|.:|.|
  Fly  1539 NLQIADLVQLVRTDLQAGVRIAVEALI---------VLDVHDRDVV------KYLTDCRI----- 1583

  Fly   698 ELCEQAQHFERMGFAIPSTMKKLYERYDTIRSLYNGIIKLALSHNRILAVLSDRERKLFRPLIQA 762
               ...|.|:.:      :..:.|.:.:.....:..:..:.......:..|.:..|.:..||...
  Fly  1584 ---TNIQDFDWI------SQLRYYWKVNEKNEDWVCVSMVVTDVEYGMEYLGNLPRLVVTPLTDR 1639

  Fly   763 CDRQLAPGVFKITYGSEFNEEFFEDGTEFIAEFQELVLIFKRANRGVARICE-----KICGTCLL 822
            |.|.|. |..|:..|...........||...:..:.|     |.:.|...|.     |..|....
  Fly  1640 CYRTLM-GALKLCLGGAPEGPAGTGKTETCKDLAKAV-----AKKCVVFNCSDGLDYKALGKFFK 1698

  Fly   823 HFAFSGS---------VDISVF----QQQLSSRLSSSGDILRSYY-----------SHVVELLSA 863
            ..|.||:         :::.|.    ||.|:.:.:....:::.::           |..:.:...
  Fly  1699 GLAQSGAWACFDEFNRIELEVLSVVAQQILTIQRAIGRKVVKFFFEDTMLKLDPTCSIFITMNPG 1763

  Fly   864 FSGQ----------FQSV-----DDEMSAEWIAYVN--DMDDMLASSLMTSARGSLNKLYEALHC 911
            ::|:          |::|     |..|..|...|.|  ||...|:..::.:.:....:|....|.
  Fly  1764 YAGRTELPDNLKVLFRTVAMMVPDYAMIGEITLYSNGFDMARNLSQKIVQAYKLCSEQLSSQSHY 1828

  Fly   912 DADMASAPIIVVESDVKDGRIVFTPDMDAIGDMINGIVD-------------SIRSMLDQFPRLG 963
            |..|.:...:::.|.......|..|:.:.:   :..|||             .|...:|.||  |
  Fly  1829 DYGMRAVKSVLLASASLRRLYVDLPEPEIV---LRAIVDVNLPKFLEQDISLFIGIYMDLFP--G 1888

  Fly   964 YKLKLPKKQQRQGFASVFREDQECSELMRSIQAEIGIQREELAKYE----------------SEW 1012
            .:|.:|::.....:..:...|       |::||......:.|..||                .:.
  Fly  1889 VELPMPQRGDILKWLHINLAD-------RNLQATPWYLEKILQIYEMLLVRHGLMIVGGSMGGKT 1946

  Fly  1013 NKNRVLWQT-----TEEE------------------------------------------FRQRL 1030
            ...:||.||     |:||                                          ||:::
  Fly  1947 TAYQVLAQTLRNVSTDEEATLKEFPVTFRIINPKAITMGQLYGRFDPVSHEWYDGVLAKTFREQV 2011

  Fly  1031 MS-KSRTAGV-FEG-----GIEHYSALADD-------------------VIFEDA---------I 1060
            .. |...|.| |:|     .||:.:.:.||                   ::||.|         :
  Fly  2012 QGPKGERAWVMFDGPVDAVWIENLNTVLDDNKKLCLMSGEIMQMTKLMNMMFEPADLEQASPATV 2076

  Fly  1061 TNVYFILINQNALKSTMLDWIEKWQALN---IKMLLDHGSNLMGAVYRYMRRNERNVMKVPRTIR 1122
            :....|.:..:.|         .|:||:   |.:|::...  :|.:|..:..:....: ||..:.
  Fly  2077 SRCGMIYMEPSQL---------GWRALHKSFINVLVNKVG--LGDIYMTLFEDMTEWL-VPAALE 2129

  Fly  1123 ETVAAKQLFEKLLKDVPVKQ-SAFTPMLELFVLLHKYQVKLSEETFEQVMGLETAWLHYLQVLEE 1186
            .....||:.|.    .|:.| ..|:.....|:..||   :.::..|:|:.....||.:...:..:
  Fly  2130 FLPQCKQMLEL----SPIYQYQTFSRFFLHFLEKHK---QFNQAWFQQMFLFCFAWAYCSALTGQ 2187

  Fly  1187 ADEMLD----------NED-SEAKLLLAKHGEKF--KLILKDFLED 1219
            ..:..|          ||: .:.|......|:.|  ||:..|:..|
  Fly  2188 GQKTFDALLRKVIYGSNENFPKPKYFSLNRGQMFPEKLLFLDYRFD 2233

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9068	NP_611111.1	DHC_N1	212..784	CDD:462457	121/677 (18%)
Dnah3	NP_647937.2	DHC_N2	1083..1489	CDD:462462	85/470 (18%)
		DYN1	<1322..4005	CDD:227570	177/1009 (18%)
		AAA_6	1620..1946	CDD:463697	61/343 (18%)
		AAA_9	3302..3523	CDD:463702
		Dynein_C	4067..4381	CDD:465677