Protein Alignment CG9068 and dnah1

DIOPT Version :10

• Sequence 1: NP_611111.1
• Gene: CG9068 / 36817
• FlyBaseID: FBgn0034106
• Length: 1227
• Species: Drosophila melanogaster
• Sequence 2: XP_009304459.3
• Gene: dnah1 / 100317899
• ZFINID: ZDB-GENE-081015-3
• Length: 4175
• Species: Danio rerio
• Alignment Length: 1201
• Identity: 224/1201 - (18%)
• Similarity: 404/1201 - (33%)
• Gaps: 380/1201 - (31%)

  Fly   213 GSLEGIAL---YWTTQIRTLLADDTLTVPHDLVTVRDEFEFWEYRYEVLQGINDQLAHSDVQKVL 274
            |..||:.|   ||..:||.|...:      |........:|.|...:..:..|  |.|..|. .:
Zfish   277 GQREGVLLESQYWVPRIRLLFCAE------DPRVFAQRVQFAENLRQNTEASN--LYHHSVD-CM 332

  Fly   275 LLLHNAQSVHMPQMD----------GL----IERARKELHKSLSNIKYLHLLIEPCSKIDAATSP 325
            .:.|    :|...::          ||    ::...|:|.|.| |::|...|.:.|........|
Zfish   333 PVWH----LHPTSLERIRKYALSTSGLQLKCLQECEKQLEKEL-NLEYSRTLNQMCFNKVVQDKP 392

  Fly   326 ADLT--KLLPRIIHLIRFIWLNSEYYNTTRLIAALFRNLSNQIIRFCTKQTKVEEILSGKPRFGI 388
            .|:|  :..|..|....|:.:.:..:...| .|.:|.:|       .|| .:|..:||
Zfish   393 EDITLPQTQPESIPERGFVSVPNYPFEKNR-AAFVFNSL-------LTK-AEVIAVLS------- 441

  Fly   389 RI---CNVAIECCLTYRGIYDTISRD-----LAQKHTQMPWELDEGLIFNHIDAFVERLND---- 441
            |:   ||...|..|.|.....::..:     .:|||:|:...|:|..:....:.....|.|
Zfish   442 RVREECNRVAEMSLFYVSFTKSLRLEEFESAQSQKHSQIHLFLEESWLPALCNGISSNLRDERCS 506

  Fly   442 -------------VIDICESMIVFGRLDEN-------GSI------------------------- 461
                         :..:|..|.:...|.::       ||:
Zfish   507 WYNLAVSRCDVYRMSKLCRLMALIRSLQQDSLRFLVQGSLASLTKLILDACHSVLQCPQELTWGP 571

  Fly   462 ----------PKPVFG-----GTCGEELEKIAESVEVQFLDTLNKLQQNSQAYILNVHRADWYAD 511
                      .||:|.     ...|.......||.|...::..:|       .||:.|
Zfish   572 DLINSPYKPKKKPLFSVDLVLDQTGVHYSTPLESFETSVINLFDK-------GILSTH------- 622

  Fly   512 VAGFRKNMQKLEETVQRLIFNVFQQVSNV---EEMLEALQAMLFYSYRQRGTLRKTYLKETSKLW 573
                  |:.::::.|...:|.|.:.:.:|   |..::.|:..:..:.:|.....|.|.:|.....
Zfish   623 ------NVPQVDKFVLPNLFIVGEVLWSVGLWEPEVKNLRESISKALKQAIIPLKAYTREYECYL 681

  Fly   574 RMFSKEMDATSRKLLEEQSRESWLSKHV-SIALGYRINLERLTWLRDRLKNSEWLPAVKESSPAL 637
            .:::.:::.    .||..|:|:...:.| ...|.:.:.:|.|         ::.:|:.....|.:
Zfish   682 ELYNSDVNT----YLELHSQENQTPQEVKQEVLEHLMEVEHL---------NKSIPSAIIIGPFM 733

  Fly   638 AKFDALRHEFQKEIRLAYDDWVAKCCGFSGDLCQRLDRYLVVRSKKFKGLLECNIDASVLEL--- 699
            ...:|:|..                              ||   ||.|||.:..:|...|.|
Zfish   734 VNVEAIRQS------------------------------LV---KKRKGLAKALLDRLALRLRQQ 765

  Fly   700 ----CEQAQHFERMGFAIPSTMKKLYERYDTIRSLYNGIIKLALSHNRILA-VLSDRERKLFRPL 759
                |::.:...:..|..||::::|.|:    |...|.:.:...:|..||: .:||.:      |
Zfish   766 MQDACKECKAISKKLFEKPSSIEELTEQ----REWMNQVPEQLKAHEEILSKAMSDYD------L 820

  Fly   760 IQACDRQLAPGVFKITYGSEF------------------NEEFFE-----DGTEFI--AEFQELV 799
            |......|:...||..:.:..                  :||.|:     |...|:  ..|.|:|
Zfish   821 IDEFYYSLSDEEFKEKWSAMAWPHKILTQMETVSAQHVDDEERFDKIQVADQNSFLERLSFLEMV 885

  Fly   800 LI-------FKRAN---RGVARI------CEKICGTCLLHFAFSGSVDISVFQQQLSSRLSSSGD 848
            :.       .:||:   ..|.|:      |:::.                   |..::|....|.
Zfish   886 VAGFSGYTNLERAHEVANEVRRVGKQLKECQEMA-------------------QLYNNRERLFGK 931

  Fly   849 ILRSYYSHVVELLSAFSGQFQSVDD--EMSAEWIAYVND-MDDMLASSLMTSARGSLNKLYEALH 910
            .:.:|..     |...:..||...|  :.:::|:.:... ::|.||:........::...|:.:|
Zfish   932 PVTNYTE-----LQKLNRDFQPFHDLWKTTSDWLRWHESWLNDPLAAINPEQLERNVTDAYKTMH 991

  Fly   911 -CDADMASAPII-VVESDVKDGRIVFTPDMDAIGDMIN-GIVDSIRSMLDQFPRLGYKLKLPKKQ 972
             |.......|.. .|.|:::.....|.|.:..|..:.| |:.:....:|.:  |:...::
Zfish   992 QCVKQFKDLPACQEVASEIRTKIEAFRPFIPLIRSLRNPGMRNRHWELLSE--RININMR----- 1049

  Fly   973 QRQGFASVFREDQECSELMRSIQAEIGIQR--EELAKYESEWNKNRVLWQT---TEEEFRQ---R 1029
                         ..:.|..|:..|:|:|.  ||:.:...|..|...:.|.   .|||:..   .
Zfish  1050 -------------SRANLTFSLCLELGLQDHVEEITRVAQEAGKEYSIEQALNKMEEEWSTVMFE 1101

  Fly  1030 LMSKSRTAGVFEGGIEHYSALADDVI--------------FEDAITNVYFILINQNALKSTMLDW 1080
            :|....|........:..|.|.||.|              ||:.|:..      ::.||.|. :.
Zfish  1102 VMPYKETGTYILKSPDEASQLLDDHIVMTQSMAFSPYKKPFEERISKW------ESKLKMTQ-EV 1159

  Fly  1081 IEKWQALNIKML----------LDHGSNLMGAVYRYMRRNERNVMKVP----RTIRETVAAK--- 1128
            :|:|.......|          ::....:.|..|:.|.|..||:||..    |.|.....|:
Zfish  1160 LEEWLICQRSWLYMEPIFSSDDINRQLPVEGKRYQTMERTWRNIMKAAHDNNRVIEVCPEARLLA 1224

  Fly  1129 ---------QLFEKLLKD-VPVKQSAFTPML-----ELFVLLHKYQVKLS-----EETFEQVMGL 1173
                     :|.:|.|.| :..|:|||....     ||..:|.:.:...|     .:.||.:
Zfish  1225 SLKDCNNLLELVQKGLSDYLETKRSAFPRFYFLSDDELLEILSQTKDPTSVQPHLRKCFENI--- 1286

  Fly  1174 ETAWLHYLQVLEEAD----EMLDNEDSEAKL 1200
              |.||:     ::|    .|..:|..|..|
Zfish  1287 --ARLHF-----QSDLLITRMYSSEGEEVHL 1310

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG9068	NP_611111.1	DHC_N1	212..784	CDD:462457	125/691 (18%)
dnah1	XP_009304459.3	DHC_N2	939..1342	CDD:462462	83/409 (20%)
		DYN1	1120..3808	CDD:227570	47/208 (23%)
		AAA_6	1468..1794	CDD:463697
		Dynein_C	3869..4171	CDD:465677