Protein Alignment CG7755 and IDH1

DIOPT Version :10

• Sequence 1: NP_611110.2
• Gene: CG7755 / 36816
• FlyBaseID: FBgn0034105
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_014361.1
• Gene: IDH1 / 855691
• SGDID: S000004982
• Length: 360
• Species: Saccharomyces cerevisiae
• Alignment Length: 353
• Identity: 104/353 - (29%)
• Similarity: 169/353 - (47%)
• Gaps: 30/353 - (8%)

  Fly    39 ADPVNVLPKSKYGGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQVIEAGQDD------EY 97
            |.....||| ||||..||:|:.|.. :|::....|.::..:..:|::.:.|...|.|      |.
Yeast    15 AQAERTLPK-KYGGRFTVTLIPGDG-VGKEITDSVRTIFEAENIPIDWETINIKQTDHKEGVYEA 77

  Fly    98 FHSVLRNRTAV----HVD-NQADAEAKQKALKICNDLDLYVFKTRTRSFPGFKCRFPGVDIQLIG 157
            ..|:.||:..:    |.. :|....:...||:  ..||:|......:|..|.|.|.|.:|:.:|.
Yeast    78 VESLKRNKIGLKGLWHTPADQTGHGSLNVALR--KQLDIYANVALFKSLKGVKTRIPDIDLIVIR 140

  Fly   158 QNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISDG-- 220
            :|..|.|:.||:..|.||||:|.|:::...::..|:||..|.|..||.||.::||....:.||
Yeast   141 ENTEGEFSGLEHESVPGVVESLKVMTRPKTERIARFAFDFAKKYNRKSVTAVHKANIMKLGDGLF 205

  Fly   221 --SLVEAAQRLHCHYKDCLELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICSGVCGGAN 283
              .:.|..|:   .|.| :::..:.|:.|..:.:.:|..||.|.....|.|.|..|.:.:.||..
Yeast   206 RNIITEIGQK---EYPD-IDVSSIIVDNASMQAVAKPHQFDVLVTPSMYGTILGNIGAALIGGPG 266

  Fly   284 LFSAVEIGDHHAVFKPLQTKLSL----TNYANLSAYGIVSTIVDLFQHLGHDKCADALWCELKRT 344
            |.:....|..:|||:|....:.|    .|.||.:|..:.||:  :..|||.::.|..:...:..|
Yeast   267 LVAGANFGRDYAVFEPGSRHVGLDIKGQNVANPTAMILSSTL--MLNHLGLNEYATRISKAVHET 329

  Fly   345 MDEGIR-TKEFGGQDTGEYVICNIINQL 371
            :.||.. |::.||..:.......|||:|
Yeast   330 IAEGKHTTRDIGGSSSTTDFTNEIINKL 357

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7755	NP_611110.2	Iso_dh	<128..371	CDD:444908	77/251 (31%)
IDH1	NP_014361.1	mito_nad_idh	26..357	CDD:272942	97/339 (29%)