Protein Alignment CG7755 and IDH3G

DIOPT Version :10

• Sequence 1: NP_611110.2
• Gene: CG7755 / 36816
• FlyBaseID: FBgn0034105
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_004126.1
• Gene: IDH3G / 3421
• HGNCID: 5386
• Length: 393
• Species: Homo sapiens
• Alignment Length: 342
• Identity: 96/342 - (28%)
• Similarity: 169/342 - (49%)
• Gaps: 19/342 - (5%)

  Fly    46 PKSKYGGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPV---EVQVIEAGQDDEYFHSVL---RN 104
            |.:||||.:||:::.|.. ||.:....|.|:...:.|||   ||.|.....:::..::::   ||
Human    47 PSAKYGGRHTVTMIPGDG-IGPELMLHVKSVFRHACVPVDFEEVHVSSNADEEDIRNAIMAIRRN 110

  Fly   105 RTA----VHVDNQADAEAKQKALKICNDLDLYVFKTRTRSFPGFKCRFPGVDIQLIGQNNMGIFN 165
            |.|    :..::......|.:...:...||||......:|.||...|...:||.::.:|..|.::
Human   111 RVALKGNIETNHNLPPSHKSRNNILRTSLDLYANVIHCKSLPGVVTRHKDIDILIVRENTEGEYS 175

  Fly   166 ELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISDGSLVEAAQRLH 230
            .||:..|.||||:|.::::..:.:...||||.|.::|||:||.::||....:.||..::..:.:.
Human   176 SLEHESVAGVVESLKIITKAKSLRIAEYAFKLAQESGRKKVTAVHKANIMKLGDGLFLQCCREVA 240

  Fly   231 CHYKDCLELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICSGVCGGANLFSAVEIGDHHA 295
            ..|.. :..|.|.|:....:|::.|..||.:.....|...::.:|:|:.||..|.:....|..:|
Human   241 ARYPQ-ITFENMIVDNTTMQLVSRPQQFDVMVMPNLYGNIVNNVCAGLVGGPGLVAGANYGHVYA 304

  Fly   296 VFKPL--QTKLSLT--NYANLSAYGIVSTIVDLFQHLGHDKCADALWCELKRTMD-EGIRTKEFG 355
            ||:..  .|..|:.  |.||.:|..:.|.:  :..||.....|.::...:..:|| |.:.|.:.|
Human   305 VFETATRNTGKSIANKNIANPTATLLASCM--MLDHLKLHSYATSIRKAVLASMDNENMHTPDIG 367

  Fly   356 GQDTGEYVICNIINQLR 372
            ||.|....|.::|..:|
Human   368 GQGTTSEAIQDVIRHIR 384

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7755	NP_611110.2	Iso_dh	<128..371	CDD:444908	72/247 (29%)
IDH3G	NP_004126.1	mito_nad_idh	52..383	CDD:272942	92/334 (28%)