Protein Alignment CG7755 and IDH3B

DIOPT Version :10

• Sequence 1: NP_611110.2
• Gene: CG7755 / 36816
• FlyBaseID: FBgn0034105
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_001317692.1
• Gene: IDH3B / 3420
• HGNCID: 5385
• Length: 387
• Species: Homo sapiens
• Alignment Length: 364
• Identity: 85/364 - (23%)
• Similarity: 166/364 - (45%)
• Gaps: 30/364 - (8%)

  Fly    30 AAYAKGDARADPVNVLPKSKYGGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQ-----VI 89
            ||:|...::|:.|.|      .|...|:::.|.. :|.:....|..:..::.||||.|     .:
Human    31 AAHAASRSQAEDVRV------EGSFPVTMLPGDG-VGPELMHAVKEVFKAAAVPVEFQEHHLSEV 88

  Fly    90 EAGQDDEYFHSVL----RNRTA----VHVDNQADAEAKQKALKICNDLDLYVFKTRTRSFPGFKC 146
            :....:|....||    .|:.|    :|...:...|.....:::...|||:......:|.||:..
Human    89 QNMASEEKLEQVLSSMKENKVAIIGKIHTPMEYKGELASYDMRLRRKLDLFANVVHVKSLPGYMT 153

  Fly   147 RFPGVDIQLIGQNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINK 211
            |...:|:.:|.:...|.::.||:....||:|.|.:|::..:.:..::||..|.|.||.:||.::|
Human   154 RHNNLDLVIIREQTEGEYSSLEHESARGVIECLKIVTRAKSQRIAKFAFDYATKKGRGKVTAVHK 218

  Fly   212 AKEWPISDGSLVEAAQRLHCHYKDCLELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICS 276
            |....:.||..::..:.:...|.. ::.|.|.::....:|:..|..||.|.....|...:..:.:
Human   219 ANIMKLGDGLFLQCCEEVAELYPK-IKFETMIIDNCCMQLVQNPYQFDVLVMPNLYGNIIDNLAA 282

  Fly   277 GVCGGANLFSAVEIGDHHAVFK-----PLQTKLSLTNYANLSAYGIVSTIVDLFQHLGHDKCADA 336
            |:.|||.:.........:|||:     |....:. .|.||.:|  ::.:..::.:||..:..:..
Human   283 GLVGGAGVVPGESYSAEYAVFETGARHPFAQAVG-RNIANPTA--MLLSASNMLRHLNLEYHSSM 344

  Fly   337 LWCELKRTMDEG-IRTKEFGGQDTGEYVICNIINQLRCR 374
            :...:|:.:..| :||::.||..|....|.::|..|:.:
Human   345 IADAVKKVIKVGKVRTRDMGGYSTTTDFIKSVIGHLQTK 383

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7755	NP_611110.2	Iso_dh	<128..371	CDD:444908	61/248 (25%)
IDH3B	NP_001317692.1	Iso_dh	47..380	CDD:444908	78/337 (23%)