Protein Alignment CG7755 and IDH3A

DIOPT Version :9

• Sequence 1: NP_611110.2
• Gene: CG7755 / 36816
• FlyBaseID: FBgn0034105
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_005521.1
• Gene: IDH3A / 3419
• HGNCID: 5384
• Length: 366
• Species: Homo sapiens
• Alignment Length: 355
• Identity: 79/355 - (22%)
• Similarity: 155/355 - (43%)
• Gaps: 54/355 - (15%)

  Fly    51 GGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQVIEAGQDDEYFHSVLRNRTAVHVDN--- 112
            ||:.||:|:.|.. ||.:.:..|..:..:::.|::.:.              ||.||:....
Human    29 GGVQTVTLIPGDG-IGPEISAAVMKIFDAAKAPIQWEE--------------RNVTAIQGPGGKW 78

  Fly   113 QADAEAKQKA-----------------------LKICNDLDLYVFKTRTRSFPGFKCRFPGVDIQ 154
            ...:|||:..                       |.:....|||.......|..|:|..:..|:|.
Human    79 MIPSEAKESMDKNKMGLKGPLKTPIAAGHPSMNLLLRKTFDLYANVRPCVSIEGYKTPYTDVNIV 143

  Fly   155 LIGQNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISD 219
            .|.:|..|.::.:|:..|:|||:::.::::..:.:...:||:.|....|..||.::||....:||
Human   144 TIRENTEGEYSGIEHVIVDGVVQSIKLITEGASKRIAEFAFEYARNNHRSNVTAVHKANIMRMSD 208

  Fly   220 GSLVEAAQRLHCHYKDCLELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICSGVCGGANL 284
            |..::..:.:....|| ::...|.::.....::.:|:.||.|.....|...||.:|:|:.||..:
Human   209 GLFLQKCREVAESCKD-IKFNEMYLDTVCLNMVQDPSQFDVLVMPNLYGDILSDLCAGLIGGLGV 272

  Fly   285 FSAVEIGDHH-AVFKPLQ---TKLSLTNYANLSAYGIVSTIVDLFQHLGHDKCADALWCELKRTM 345
            ..:..||.:. |:|:.:.   ..::..:.||.:|  ::.:.|.:.:|:|....|..:......|:
Human   273 TPSGNIGANGVAIFESVHGTAPDIAGKDMANPTA--LLLSAVMMLRHMGLFDHAARIEAACFATI 335

  Fly   346 DEG-IRTKEFGGQDTGEYVICNIINQLRCR 374
            .:| ..||:.||.     ..|:...:..||
Human   336 KDGKSLTKDLGGN-----AKCSDFTEEICR 360

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7755	NP_611110.2	Iso_dh	51..371	CDD:294303	77/350 (22%)
IDH3A	NP_005521.1	mito_nad_idh	29..362	CDD:272942	79/355 (22%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0473
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S361
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000244
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	4	3.760