Protein Alignment CG7755 and idh1

DIOPT Version :10

• Sequence 1: NP_611110.2
• Gene: CG7755 / 36816
• FlyBaseID: FBgn0034105
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_594397.1
• Gene: idh1 / 2541894
• PomBaseID: SPAC11G7.03
• Length: 356
• Species: Schizosaccharomyces pombe
• Alignment Length: 346
• Identity: 88/346 - (25%)
• Similarity: 157/346 - (45%)
• Gaps: 48/346 - (13%)

  Fly    49 KYGGINTVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQVIEAGQDDEYFHSVLRNRTAVHVDNQ 113
            ||||..||:|:.|.. ||::.:..|:.:..::.||:|.:.|:.              |.:..:|:
pombe    16 KYGGKYTVTLIPGDG-IGRETSNAVTEIFKTANVPIEFEEIDV--------------TGMEKNNK 65

  Fly   114 ADAEAKQKALK----------------------------ICNDLDLYVFKTRTRSFPGFKCRFPG 150
            :..:|..:|::                            :..:||:|......::.||||.|...
pombe    66 SSGDALHEAIQSLKRNKVGLKGILFTPFEKGGHTSFNVALRKELDIYASLVLIKNIPGFKTRHDN 130

  Fly   151 VDIQLIGQNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEW 215
            ||..:|.:|..|.::.||:..|.||||:|.::::..:.:..::||..|.:.|||.||.|:||...
pombe   131 VDFAIIRENTEGEYSGLEHQSVPGVVESLKIITEYKSKRIAQFAFDFALQNGRKSVTCIHKANIM 195

  Fly   216 PISDGSLVEAAQRLHCHYKDCLELELMEVEEAISRLMTEPTYFDCLFASERYATFLSAICSGVCG 280
            .::||........:...| |.:..:.:.|:.|..:.::.|..||.|.....|.:.||.|.|.:.|
pombe   196 KLADGLFRRTFYDVANGY-DAITPKDLIVDNASMQAVSRPQQFDVLVMPNLYGSILSNIGSALVG 259

  Fly   281 GANLFSAVEIGDHHAVFKP--LQTKLSLTNYANLSAYGIVSTIVDLFQHLGHDKCADALWCELKR 343
            |..:......|..:|:|:|  ....||:|.....:....:.:...:.:|||....||.:......
pombe   260 GPGVIPGANFGRDYALFEPGCRHVGLSITGRGEANPTAAILSACLMLRHLGLKDYADLINAATYS 324

  Fly   344 TMDEG-IRTKEFGGQ-DTGEY 362
            .::|| ..||:.||. .||::
pombe   325 VIEEGKTLTKDLGGSASTGDF 345

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7755	NP_611110.2	Iso_dh	<128..371	CDD:444908	69/239 (29%)
idh1	NP_594397.1	mito_nad_idh	18..353	CDD:272942	86/344 (25%)