Protein Alignment CG7755 and idh2

DIOPT Version :10

• Sequence 1: NP_611110.2
• Gene: CG7755 / 36816
• FlyBaseID: FBgn0034105
• Length: 378
• Species: Drosophila melanogaster
• Sequence 2: NP_595203.2
• Gene: idh2 / 2541260
• PomBaseID: SPBC902.05C
• Length: 379
• Species: Schizosaccharomyces pombe
• Alignment Length: 358
• Identity: 84/358 - (23%)
• Similarity: 175/358 - (48%)
• Gaps: 50/358 - (13%)

  Fly    50 YGGIN------TVSLVTGTTIIGQQGAQFVSSLLSSSRVPVEVQVIEAGQDDEYFHSVLRNRTAV 108
            |.|:.      ||:::.|.. ||.:.||.|..:..:::||:|.:.::.       :.:|:|.|..
pombe    37 YEGVKNANGNYTVTMIAGDG-IGPEIAQSVERIFKAAKVPIEWERVKV-------YPILKNGTTT 93

  Fly   109 HVDNQADAEAKQK-ALK-----------------ICNDLDLYVFKTRTRSFPGFKCRFPGVDIQL 155
            ..|:..::..|.| |||                 :.....|:.......|..|:|..:..|:..|
pombe    94 IPDDAKESVRKNKVALKGPLATPIGKGHVSMNLTLRRTFGLFANVRPCVSITGYKTPYDNVNTVL 158

  Fly   156 IGQNNMGIFNELEYSPVEGVVEALSVVSQKGNDKYLRYAFKAAAKAGRKRVTLINKAKEWPISDG 220
            |.:|..|.::.:|:..:.|||:::.::::..:::.:||||:.|.:.|:..:|:::||....::||
pombe   159 IRENTEGEYSGIEHEVIPGVVQSIKLITRAASERVIRYAFQYARQTGKNNITVVHKATIMRMADG 223

  Fly   221 SLVEAAQRLHCHYKDCLELELME--VEEAISRLMTEPTYFD--CLFASERYATFLSAICSGVCGG 281
            ..:|.|:.|...|.|   :||.|  ::.|..:::|:|..::  .:.....|...:|.:|:|:.||
pombe   224 LFLECAKELAPEYPD---IELREEILDNACLKIVTDPVPYNNTVMVMPNLYGDIVSDMCAGLIGG 285

  Fly   282 ANLFSAVEIGDHHAVFKPLQ---TKLSLTNYANLSAYGIVSTIVDLFQHLGHDKCA----DALWC 339
            ..|..:..||:..::|:.:.   ..::....||.:|. ::|::: :.:|:..:..|    .|::.
pombe   286 LGLTPSGNIGNQASIFEAVHGTAPDIAGKGLANPTAL-LLSSVM-MLKHMNLNDYAKRIESAIFD 348

  Fly   340 ELKRTMDEGIRTKEFGGQDTGEYVICNIINQLR 372
            .|....|  .|||:.||:.........||::|:
pombe   349 TLANNPD--ARTKDLGGKSNNVQYTDAIISKLK 379

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7755	NP_611110.2	Iso_dh	<128..371	CDD:444908	61/253 (24%)
idh2	NP_595203.2	Iso_dh	44..378	CDD:444908	81/348 (23%)