Protein Alignment cato and HAND2

DIOPT Version :10

• Sequence 1: NP_477344.1
• Gene: cato / 36813
• FlyBaseID: FBgn0024249
• Length: 189
• Species: Drosophila melanogaster
• Sequence 2: NP_068808.1
• Gene: HAND2 / 9464
• HGNCID: 4808
• Length: 217
• Species: Homo sapiens
• Alignment Length: 143
• Identity: 47/143 - (32%)
• Similarity: 63/143 - (44%)
• Gaps: 26/143 - (18%)

  Fly    29 PPVSGQDYGQGAFLSPEWQFLDAAGGTQTELGPIMEAQGQHTQPQTKRRSNSFTGSDGRKSSPEQ 93
            |.:|..||......|||:. ..|||...:..|.:....|.             .|..|.:
Human    51 PEMSPPDYSMALSYSPEYA-SGAAGLDHSHYGGVPPGAGP-------------PGLGGPR----- 96

  Fly    94 TNLSPTVQKRRRQAANARERKRMNGLNAAFERLREVVPAPSIDQKLSKFETLQMAQSYILALCDL 158
                |.   :||..||.:||:|...:|:||..|||.:|....|.||||.:||::|.|||..|.||
Human    97 ----PV---KRRGTANRKERRRTQSINSAFAELRECIPNVPADTKLSKIKTLRLATSYIAYLMDL 154

  Fly   159 LNNGDVEVDAAAY 171
            |...|...:|.|:
Human   155 LAKDDQNGEAEAF 167

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cato	NP_477344.1	bHLH_TS_ATOH1_like	104..159	CDD:381436	27/54 (50%)
HAND2	NP_068808.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	76..116		12/64 (19%)
		bHLH_TS_HAND2	100..161	CDD:381477	30/60 (50%)