DRSC/TRiP Functional Genomics Resources

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back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment cato and neurod6

DIOPT Version :9

Sequence 1:NP_477344.1 Gene:cato / 36813 FlyBaseID:FBgn0024249 Length:189 Species:Drosophila melanogaster
Sequence 2:NP_001072273.1 Gene:neurod6 / 779726 XenbaseID:XB-GENE-969227 Length:337 Species:Xenopus tropicalis


Alignment Length:106 Identity:41/106 - (38%)
Similarity:61/106 - (57%) Gaps:5/106 - (4%)


- Green bases have known domain annotations that are detailed below.


  Fly    62 IMEAQGQHTQPQTKRRSNSFTGSDG--RKSSPEQTNLSPTVQKR---RRQAANARERKRMNGLNA 121
            |..:..:.|:.:.:.........:|  |:..|.:..::....:|   ||..||||||.||:|||.
 Frog    48 IKRSPEEETEQEEEDEDREEEDENGLPRRRGPRKKKMTKVRIERIKVRRVEANARERGRMHGLND 112

  Fly   122 AFERLREVVPAPSIDQKLSKFETLQMAQSYILALCDLLNNG 162
            |.:.||:|||..|..|||||.|||::|::||.||.::|..|
 Frog   113 ALDNLRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRIG 153

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
catoNP_477344.1 HLH 104..155 CDD:278439 31/50 (62%)
neurod6NP_001072273.1 bHLH_TS_NeuroD4_ATOH3 74..151 CDD:381564 36/76 (47%)
Neuro_bHLH 153..272 CDD:372170 1/1 (100%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R2611
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
21.940

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