Protein Alignment cato and ASCL1

DIOPT Version :10

• Sequence 1: NP_477344.1
• Gene: cato / 36813
• FlyBaseID: FBgn0024249
• Length: 189
• Species: Drosophila melanogaster
• Sequence 2: NP_004307.2
• Gene: ASCL1 / 429
• HGNCID: 738
• Length: 236
• Species: Homo sapiens
• Alignment Length: 189
• Identity: 56/189 - (29%)
• Similarity: 79/189 - (41%)
• Gaps: 33/189 - (17%)

  Fly     6 SSASEEDGSSQYLGSPNYNLTQLPPVSGQDYGQGAFLSPEWQFLDAAGGTQTELGPIMEAQGQHT 70
            |||..|.|.:.....|......|||.:       .|.:.......||.....:.....:.|.|..
Human     3 SSAKMESGGAGQQPQPQPQQPFLPPAA-------CFFATAAAAAAAAAAAAAQSAQQQQQQQQQQ 60

  Fly    71 Q--PQTKRRSNSFTGSDGRKSSPEQT----NLSPTVQKRRRQ---------------AA----NA 110
            |  ||.:..::......|.||:|:|.    :.||.:.:.:|:               ||    |.
Human    61 QQAPQLRPAADGQPSGGGHKSAPKQVKRQRSSSPELMRCKRRLNFSGFGYSLPQQQPAAVARRNE 125

  Fly   111 RERKRMNGLNAAFERLREVVPAPSIDQKLSKFETLQMAQSYILALCDLLNNGDVEVDAA 169
            |||.|:..:|..|..|||.||..:.::|:||.|||:.|..||.||..||:..|. |.||
Human   126 RERNRVKLVNLGFATLREHVPNGAANKKMSKVETLRSAVEYIRALQQLLDEHDA-VSAA 183

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cato	NP_477344.1	bHLH_TS_ATOH1_like	104..159	CDD:381436	26/73 (36%)
ASCL1	NP_004307.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..26		6/22 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	42..98		13/55 (24%)
		bHLH_TS_ASCL1_Mash1	115..185	CDD:381585	31/70 (44%)