DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cato and neurod1

DIOPT Version :9

Sequence 1:	NP_477344.1	Gene:	cato / 36813	FlyBaseID:	FBgn0024249	Length:	189	Species:	Drosophila melanogaster
Sequence 2:	NP_571053.1	Gene:	neurod1 / 30169	ZFINID:	ZDB-GENE-990415-172	Length:	350	Species:	Danio rerio

Alignment Length:	102	Identity:	45/102 - (44%)
Similarity:	60/102 - (58%)	Gaps:	17/102 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    64 EAQGQHTQPQTKRRSNSFTGSDGRKSSPEQTNLSPTVQKR---RRQAANARERKRMNGLNAAFER 125
            |..|..|:|  |||            .|::..::....:|   ||..||||||.||:|||.|.|.
Zfish    68 EEDGDDTKP--KRR------------GPKKKKMTKARMQRFKMRRMKANARERNRMHGLNDALES 118

  Fly   126 LREVVPAPSIDQKLSKFETLQMAQSYILALCDLLNNG 162
            ||:|||..|..|||||.|||::|::||.||.::|.:|
Zfish   119 LRKVVPCYSKTQKLSKIETLRLAKNYIWALSEILRSG 155

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cato	NP_477344.1	HLH	104..155	CDD:278439	32/50 (64%)
neurod1	NP_571053.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..91		8/36 (22%)
		Nuclear localization signal. /evidence=ECO:0000255	82..88		0/5 (0%)
		HLH	95..153	CDD:238036	34/57 (60%)
		Neuro_bHLH	155..277	CDD:289310	1/1 (100%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2611
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.940