Protein Alignment Khc and AT2G36200

DIOPT Version :10

• Sequence 1: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001189688.1
• Gene: AT2G36200 / 818192
• AraportID: AT2G36200
• Length: 1040
• Species: Arabidopsis thaliana
• Alignment Length: 1136
• Identity: 304/1136 - (26%)
• Similarity: 494/1136 - (43%)
• Gaps: 261/1136 - (22%)

  Fly     1 MSAEREIPAEDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCIS--IAGK----VYLFDKVF 59
            ||:..:.....:::|:.|.||.:|.|.::.:..|:...:...|..:|  ||||    |:.|||||
plant     1 MSSRHDKEKGVNVQVLLRCRPFSDDELRSNAPQVLTCNDLQREVAVSQNIAGKHIDRVFTFDKVF 65

  Fly    60 KPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVI---------GDSVKQGII 115
            .|:|.|:.:|::|...||.:||.|:|.||||||||.:|||:||||..         |...:.|:|
plant    66 GPSAQQKDLYDQAVVPIVNEVLEGFNCTIFAYGQTGTGKTYTMEGECRRSKSAPCGGLPAEAGVI 130

  Fly   116 PRIVNDIFNHIYAMEVNLEFHIKVSYYEIYMDKIRDLL---DVSKVNLSVHEDKNRVP------- 170
            ||.|..||:.:...:.  |:.:||::.|:|.::|.|||   |:|:|   ..|:|.:.|
plant   131 PRAVKQIFDTLEGQQA--EYSVKVTFLELYNEEITDLLAPEDLSRV---AAEEKQKKPLPLMEDG 190

  Fly   171 ----YVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVF--LINVKQENLENQKK 229
                .|:|..|..|:|..::|.::|.|.|.|..|.|.:|:.||||||:|  .|::|:...|.::.
plant   191 KGGVLVRGLEEEIVTSANEIFTLLERGSSKRRTAETFLNKQSSRSHSLFSITIHIKEATPEGEEL 255

  Fly   230 LS-GKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNKTHIPYRDSKLTRI 293
            :. |||.||||||||.:|::||......||..|||||..||.|||||.: :..|:|||||||||:
plant   256 IKCGKLNLVDLAGSENISRSGARDGRAREAGEINKSLLTLGRVISALVE-HLGHVPYRDSKLTRL 319

  Fly   294 LQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEK 358
            |::||||..:|.|:...|||.....||.||||:..|||.::|...||:::    .|....|:
plant   320 LRDSLGGRTKTCIIATVSPAVHCLEETLSTLDYAHRAKNIRNKPEVNQKM----MKSTLIKD--- 377

  Fly   359 NARLKGKVEKLEIEL--ARWRAGETVKAEEQINMEDLMEASTPNLEVEAAQTAAAE--AALAAQR 419
               |.|::|:|:.|:  :|.:.|..:..|.....|...:.....:|....|....:  :.....|
plant   378 ---LYGEIERLKAEVYASREKNGVYMPKERYYQEESERKVMAEQIEQMGGQIENYQKVSFFLLCR 439

  Fly   420 TALANMSASVAVNE--------------------QARLATECERLYQQLDDKDEEINQQSQYA-- 462
            :........:.||.                    |.|   ||..|..:||..::.::|..:..
plant   440 SKFYTYMWELHVNNGYLHICCDQQLEELQDKYVGQVR---ECSDLTTKLDITEKNLSQTCKVLAS 501

  Fly   463 --EQLK--EQVMEQEELIANARREYET--------LQSEMARIQQENESAKEEV--KEVLQALEE 513
              |:||  :..|::::.|.:.:::.|.        |||.:.:..::|.|..:::  ::.|.|...
plant   502 TNEELKKSQYAMKEKDFIISEQKKSENVLVQQACILQSNLEKATKDNSSLHQKIGREDKLSADNR 566

  Fly   514 LAV-NYD-QKSQEIDN-----------KNKDIDALNEELQQKQSVFNAASTELQQ----LKDM-S 560
            ..| ||. :.|::|.|           :|..:..:|:..|.:....|.|..|:::    .:|: |
plant   567 KVVDNYQVELSEQISNLFNRVASCLSQQNVHLQGVNKLSQSRLEAHNKAILEMKKKVKASRDLYS 631

  Fly   561 SHQKKRITEMLTNLLR--------DLGEVG-----------QAIAPGE----SSIDLKMSALAG- 601
            ||     .|.:.|::|        .|.||.           :.:|.|:    |..|...|||:.
plant   632 SH-----LEAVQNVVRLHKANANACLEEVSALTTSSACSIDEFLASGDETTSSLFDELQSALSSH 691

  Fly   602 ----------------TDASKVEEDFTMARLFISKMKTEAKNIAQRCSNMETQQADS-------- 642
                            |...:.:|.......|..|:..|:||...|.:.....|.:|
plant   692 QGEMALFARELRQRFHTTMEQTQEMSEYTSTFFQKLMEESKNAETRAAEANDSQINSIIDFQKTY 756

  Fly   643 -NKKISEYEKDLGEYRLLISQHEARMKSLQES----MREAENKKRTLEEQIDSLREECAKLKAAE 702
             .:..|:.:|.:.:...|:|.|..|...|.:|    .::|.:..:|..:               |
plant   757 EAQSKSDTDKLIADLTNLVSSHIRRQHELVDSRLHNFKDAVSSNKTFLD---------------E 806

  Fly   703 HVSAVN--AEEKQRAEELRSMFDSQMDELREA-------HTRQVSELRDEIAAKQHEMDEMKDVH 758
            ||||||  .::.:|..|..||  ...:|.||.       |.|....|:..:...:......|..|
plant   807 HVSAVNNLTKDAKRKWETFSM--QAENEAREGADFSAAKHCRMELLLQQSVGHAESAFKHCKITH 869

  Fly   759 QKLL-LAHQQMTADYEKVR-------QEDAEKSSELQNIILTNERREQARKDLKGLEDTVAKELQ 815
            :.|. :..:|:|.....||       |.|||..|          .|..|.||:....|.:.::::
plant   870 ESLKEMTSKQVTDVSSLVRSACDSNEQHDAEVDS----------ARTAAEKDVTKNSDDIIQQIE 924

  Fly   816 TLHNLRKLFVQDLQQRIRKNVVNEES-EEDGGSLAQKQKISFLENNLDQLTKVHKQLVRDNADLR 879
            .:....|..|..:.:.:|.:....|| ::|  ...|.:.|.      |:..:..:|...:.....
plant   925 RMSEDEKASVSKILENVRSHEKTLESFQQD--QCCQARCIE------DKAQETFQQQYMEYEPTG 981

  Fly   880 CELPKLEKRL--RCTMERVKA--LETALKEAKEGAMRDRKRYQYEVDRIKEAVRQKHLGRRGPQA 940
            ....|.|..:  :.|:|.::|  :||.::|.:|       ...||....||...|
plant   982 ATPTKNEPEIPTKATIESLRAMPIETLVEEFRE-------NNSYESFATKETKPQ---------- 1029

  Fly   941 QIAKPIRSGQGAIAIRGGGAVGGPSPLAQVN 971
            |:.:                    |||:|||
plant  1030 QLTR--------------------SPLSQVN 1040

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	148/354 (42%)
		Smc	<341..>807	CDD:440809	119/593 (20%)
		Khc_CBD_cc	856..925	CDD:467880	13/72 (18%)
AT2G36200	NP_001189688.1	KISc_BimC_Eg5	10..368	CDD:276815	151/363 (42%)