Protein Alignment Khc and Kif17

DIOPT Version :9

• Sequence 1: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: XP_038967234.1
• Gene: Kif17 / 500571
• RGDID: 1562511
• Length: 1075
• Species: Rattus norvegicus
• Alignment Length: 1029
• Identity: 290/1029 - (28%)
• Similarity: 445/1029 - (43%)
• Gaps: 238/1029 - (23%)

  Fly     9 AEDSIKVVCRFRPLNDSEEKAGSKFVV-----------KFPNNVEENCISIAGKVYLFDKVFKPN 62
            |.:|:|||.|.||:|..|.:...:.||           :.|...:|     ..|.:.||..:...
  Rat     2 ASESVKVVVRCRPMNKRERELNCQSVVTVDCARGQCFIQNPGAADE-----PPKQFTFDGAYYIE 61

  Fly    63 ASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIY 127
            ...|::|||.|..:|..|..||||||||||||.|||:.||:|:.....::|||||....:|..:.
  Rat    62 HFTEQIYNEIAYPLVEGVTEGYNGTIFAYGQTGSGKSFTMQGLPDPPCQRGIIPRAFEHVFESVQ 126

  Fly   128 AMEVNLEFHIKVSYYEIYMDKIRDLLDV-SKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIE 191
            ..| |.:|.::.||.|||.:.:||||.. :|..|.:.|...:..||||.:...|.:......|:|
  Rat   127 CAE-NTKFLVRASYLEIYNEDVRDLLGADTKQRLELKEHPEKGVYVKGLSMHTVHNVAQCERVME 190

  Fly   192 EGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKK---LSGKLYLVDLAGSEKVSKTGAEGT 253
            .|..||.:..|.||:.||||||:|.||::...::.:.|   .:|||.||||||||:.|||||.|.
  Rat   191 TGWKNRAVGYTLMNKDSSRSHSIFTINIEIYAVDERGKDHLRAGKLNLVDLAGSERQSKTGATGE 255

  Fly   254 VLDEAKNINKSLSALGNVISALADGNKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNES 318
            .|.||..||.||||||||||||.||...|||||||||||:||:|||||.:|.:|.|.|||..|..
  Rat   256 RLKEATKINLSLSALGNVISALVDGRCKHIPYRDSKLTRLLQDSLGGNTKTLMVACLSPADNNYD 320

  Fly   319 ETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEKNARLKGKVEKLEIELARWRAGETVK 383
            ||.|||.:..|||.:||...:||: ..:...|.|::|          :::|:..||
  Rat   321 ETLSTLRYANRAKNIKNKPRINED-PKDALLREYQEE----------IKRLKAILA--------- 365

  Fly   384 AEEQI---NMEDLMEASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQARLATECERLY 445
              :|:   |:..|:...||:..|.      .|..|.:..|.
  Rat   366 --QQMGPGNLSALLSTQTPSGPVH------PEEKLPSPTTV------------------------ 398

  Fly   446 QQLDDKDEEINQQSQYAEQLKEQVMEQ-EELIANARREYETLQSEMARIQQENESAKEEVKEVLQ 509
                       ||...||  |:.:.|: ||.:|..:.:||..|....|:|::
  Rat   399 -----------QQDTEAE--KQMIREEYEERLARLKADYEAEQESRVRLQED------------- 437

  Fly   510 ALEELAVNYDQK---SQEIDNKNKDIDAL--------------------NEELQQKQSVFNAAST 551
             :..:..:||.|   .||...|.|:..||                    ..|...|..|.  ..|
  Rat   438 -ITAMRNSYDVKLSTLQENLRKEKETGALCPGAAWEPTSCVPYTWAKGPLHEAVLKAEVL--CKT 499

  Fly   552 ELQQLKDMSSHQ------------KKRITEMLTNLLRDLGEVGQAIAP---GESSIDLKMSALAG 601
            |:....:::|..            |..:..|...|.|  |||.::.||   .|.:::...|.:..
  Rat   500 EVMSRAEVTSGPEYSPPLQYETAVKPTVLSMPDMLPR--GEVTRSQAPLTSEEPNMEPSRSEVFE 562

  Fly   602 TDASKVEEDFTMARLFISKMKTEAKNIAQRCSNMETQQ----ADSNKKISEYEKDLGEYRLLISQ 662
            ::.|...||.:|         :||....:..||:|...    |:|.....||.........|.::
  Rat   563 SNESSNLEDSSM---------SEAYPGPEELSNVEFSMPGVLAESRYFPDEYLNPEAAGCPLEAE 618

  Fly   663 HEAR----------MKSLQESMREAENK-------------KRTLEEQIDSLREECAK-LKAAEH 703
            |..:          :.|||:...|.|.|             .:|:..|:...:..... |:.::.
  Rat   619 HSVQDEPTLEPLRILASLQDPFAEVEAKLARLSSTVAMTDLSQTVVPQVPQQQPSSTDLLEPSDT 683

  Fly   704 VSAVNAEEK-----------QRAEELRSMFDSQMDELREAHTRQVSELRDEIAAKQHEMDEMKDV 757
            .|.|:..:.           :.|||:.|..::.:....|||...|:::.:|  |:...:..|..|
  Rat   684 KSEVDVADNVLLRTEPDLSMKVAEEVVSEAETGVWMESEAHVAHVAQVSEE--AQPQPLLAMASV 746

  Fly   758 HQKLLLAHQQMTADYEKVRQEDAEKSSELQNI----ILTNERREQARKDLKGLEDTVAKELQTLH 818
            .:             |.:..|.|..:.|||.:    :|.  |.:...:.:.|.|....|:|:..|
  Rat   747 RR-------------ESIGVEVAVLTEELQPVDQQQVLA--RLQLLEQQVVGGEQAKNKDLKEKH 796

  Fly   819 NLRKLFVQDLQQRIRKNVVNEESEEDGGSLAQKQKISFLENNLDQLTKVHKQLVRDNADLRCELP 883
            ..||.:..:.::::...:.|  |:||.|...       |.|..|.:    ::.||..:.|   |.
  Rat   797 RRRKRYADERKKQLVAALQN--SDEDSGDWV-------LLNVYDSI----QEEVRAKSKL---LE 845

  Fly   884 KLEKRLRCTMERVKALETALKEAKEGAM-------RDRKRYQYEVDRIKEAVRQ 930
            |::|:||.....:|.|::..:..|...:       ||...:|..:::::..:|:
  Rat   846 KMQKKLRAAEVEIKDLQSEFQLEKIDYLATIRRQERDSMLFQQLLEQVQPLIRR 899

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	154/337 (46%)
		KISc	12..340	CDD:214526	156/342 (46%)
		Apolipoprotein	595..744	CDD:279749	35/187 (19%)
Kif17	XP_038967234.1	Motor_domain	4..335	CDD:419868	154/336 (46%)
		Smc	<631..>899	CDD:224117	60/300 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910