Protein Alignment Khc and pav

DIOPT Version :9

• Sequence 1: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_477025.1
• Gene: pav / 38515
• FlyBaseID: FBgn0011692
• Length: 887
• Species: Drosophila melanogaster
• Alignment Length: 1088
• Identity: 240/1088 - (22%)
• Similarity: 387/1088 - (35%)
• Gaps: 370/1088 - (34%)

  Fly     9 AEDSIKVVCRFRPLNDSEEKAGSKFVVK-----------------FPNNVEENCISIAGKVYLFD 56
            |.|.:.|.||.|||....:....:  ||                 .|:|..:..:.     |:|.
  Fly    33 ARDPVNVFCRVRPLQSDADLTSLR--VKNSTTIALNPQDQLLQHHKPHNGAQREVQ-----YIFK 90

  Fly    57 KVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVND 121
            .||:|:|:|:.||...|:.:|.::|.|.|..:|.||.|.||||:||.|.:.   .:||:||.::.
  Fly    91 HVFQPDATQQDVYAAVAQPLVENLLKGRNSLLFTYGVTGSGKTYTMTGNLR---HRGIMPRCLDV 152

  Fly   122 IFNHI------------------------------------------------------YAMEVN 132
            :|..|                                                      .|.:.:
  Fly   153 LFRTISDYQAKKFVFKPDKLNGFEILSEEDALLERQHEMNQRFAGSGRFAFRHKDSDPEIASQAS 217

  Fly   133 LE------------FHIKVSYYEIYMDKIRDLLDVSKVNLS-----VHEDKNRVPYVKGATERFV 180
            :|            :.:.|:|.|||.:.:.|||:.|.:..:     :.||.||..:|.|.||..|
  Fly   218 VEPIPLLGLDEDNMYSVFVTYIEIYNNSVYDLLEDSGIQKTLQSKIIREDANRHMFVHGVTEVEV 282

  Fly   181 SSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQ-------ENL--ENQKKLSGKLYL 236
            .:.||..||.:.|:..:.:..|.:|..||||||||.|.:.|       ||:  :.|.....:|.|
  Fly   283 KTVEDALEVFQMGQKRKRMGHTVLNAESSRSHSVFNIRLVQAPTDSQGENVVQDRQNITVSQLSL 347

  Fly   237 VDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGN--------KTHIPYRDSKLTRI 293
            |||||||:.|:|...|..|.||.|||.||..|...:..|.:..        ...:||||||:|.:
  Fly   348 VDLAGSERSSRTKNTGVRLREAGNINNSLMTLRTCLEYLRENQLAASNGLAPKKVPYRDSKITHM 412

  Fly   294 LQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEK 358
            .:....|..:.::::|.:|...:..|....:.|.              |:|.
  Fly   413 FKNYFDGEGQVSMIVCINPRIEDYDENMQVMKFA--------------EMTQ------------- 450

  Fly   359 NARLKGKVEKLEIELARWRAGETVKAEEQINMEDLMEASTPNLEVEAAQTAAAEAALAAQRTALA 423
                       |:::||                     :||..:         :..|...|.. |
  Fly   451 -----------EVQIAR---------------------ATPMKQ---------DLGLTPGRRK-A 473

  Fly   424 NMSASVAVNEQARLATECERLYQQLDDKDEEINQQSQYAEQLKEQVMEQEELIANARREYETLQS 488
            |....:|||....|...        :.||.|::....|                       :|..
  Fly   474 NKLFKIAVNNLNELGIP--------EAKDLEVDVGLVY-----------------------SLGP 507

  Fly   489 EMARIQQENESAKEEVKEVLQALEE-------LAVNYDQKSQEIDNKNKDIDALNEELQQKQSVF 546
            :....:.::..|:.:::|::..||:       |..|.|.|.........::|..|.:|:
  Fly   508 DFPAYEMDSPEAQIKIRELMHYLEQRIEKRKKLRANLDIKCDSFRQMLMNLDRDNLQLR------ 566

  Fly   547 NAASTELQQLKDMSSHQKKRITEMLTNLLRDLGEVGQAIAPGESSIDLKMSALAGTDASKVE--- 608
                |||..||.:...::.|...:           .:.:...|||||:..:.|     ||.|
  Fly   567 ----TELASLKAVYKQERDRSAAL-----------EKKVRIHESSIDVLNNTL-----SKQERQI 611

  Fly   609 EDFTMARLFISKMKTEAKNIAQRCSNMETQQADSNKKIS-EYEKDLGEYRLLISQHEARMKSLQE 672
            |:.|.      |:..:...:.|:....|.|:...:.|:: |.:|:..|:.|.:  .|.|:| |||
  Fly   612 EELTF------KLNEKENMLTQKEHEKEKQKKKFSSKLAVESDKNKREFELKL--REQRVK-LQE 667

  Fly   673 SMREAENKKRTLEEQIDSLREECAKLKAAEHVSAVNAEEKQRAEELRSMFDSQMDELREAHTRQV 737
            .||..:.|.|.:...:.|  |:...|..::      :.|....|:.|..:.::.:|.....||
  Fly   668 RMRIKDEKLRLVSNILQS--EDLPSLPRSQ------SSENILNEKDRGAYTARTEESSVPATR-- 722

  Fly   738 SELRDEIAAKQHEMDEMKDVHQKLLLAHQQMTADYEKVRQEDAEKSSELQNII---LTNERREQA 799
               .|..|..:|......:.|::...|.       :|..:..|.....|..|:   |.|
  Fly   723 ---TDIYATPRHGAAAANNRHRRSRSAG-------DKWLEHRAANPVPLGTIMQPYLKN------ 771

  Fly   800 RKDLKGLEDTVAKELQTLHNLRKLFVQDLQQRIRKNVVNEESEEDGGSLAQKQKISFLENNLDQL 864
            ||.:..|.|  .||| |.|...|..           :|:::::.||                |..
  Fly   772 RKSVTKLTD--LKEL-TAHGTTKYC-----------LVSQDADTDG----------------DVE 806

  Fly   865 TKVHKQLVRDNADLRCELPKLEKRLRCTMERVKALETALKEAKEGAMRDRKRYQYEVDRIKEAVR 929
            ||::|..|         :|......:.....|                             |.::
  Fly   807 TKLYKGNV---------IPTCGGGAQVVFNDV-----------------------------ECLK 833

  Fly   930 QKHLGRRGPQAQIAKPIRS--GQGAIAIRGGGAVGGPSPLAQVNPVNS 975
            ||        :.:..|.|.  ..|.|:..|||||  ||.:.....|.|
  Fly   834 QK--------SPVHSPTRKRPSNGNISALGGGAV--PSTVTSAQDVAS 871

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	116/427 (27%)
		KISc	12..340	CDD:214526	115/432 (27%)
		Apolipoprotein	595..744	CDD:279749	35/152 (23%)
pav	NP_477025.1	KISc_KIF23_like	35..450	CDD:276819	117/438 (27%)
		Kinesin	42..452	CDD:278646	115/457 (25%)
		MKLP1_Arf_bdg	735..837	CDD:293148	31/190 (16%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437966
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940