Protein Alignment Khc and cana

DIOPT Version :9

• Sequence 1: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001027247.1
• Gene: cana / 3771934
• FlyBaseID: FBgn0040233
• Length: 1931
• Species: Drosophila melanogaster
• Alignment Length: 1154
• Identity: 283/1154 - (24%)
• Similarity: 490/1154 - (42%)
• Gaps: 278/1154 - (24%)

  Fly    12 SIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIA---GKVYLFDKVFKPNASQEKVYNEAA 73
            ||:|..:.||   .|....|.:.||     |...|.:|   .:.|:||.||...||.::|::..|
  Fly     8 SIQVCIKVRP---CEPGLTSLWQVK-----EGRSIQLADSHAEPYVFDYVFDEGASNQEVFDRMA 64

  Fly    74 KSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSVKQGIIPRIVNDIFNHIYAMEVNLEFHIK 138
            |.||...:.|.|||||||||||||||:||   :||....|::.....:||..| :.|...:|.::
  Fly    65 KHIVHACMQGSNGTIFAYGQTSSGKTYTM---MGDEQNPGVMVLAAKEIFQQI-SSETERDFLLR 125

  Fly   139 VSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTN 203
            |.|.|||.:||.|||:....:|.:||..|.:..| ...|..|:|.:|:...:..|...|.:..||
  Fly   126 VGYIEIYNEKIYDLLNKKNQDLKIHESGNGIVNV-NCKESIVTSEDDLLRQLYMGNKERVVGETN 189

  Fly   204 MNEHSSRSHSVFLINV---KQENLENQKKLSGKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSL 265
            |||.|||||::|.|.:   |.::.:|.......|.||||||||:|...       |.|    .||
  Fly   190 MNERSSRSHAIFRIIIESRKSDHSDNDTVKQSVLSLVDLAGSEQVDPA-------DHA----SSL 243

  Fly   266 SALGNVISALADG--NKTHIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGR 328
            ....|::.:|::.  :|.: .:|||||.||:..|||||..|:| ||....||.| |:.||:.||.
  Fly   244 MIFRNLVKSLSESVDSKPN-SFRDSKLPRIMLPSLGGNVLTSI-ICTITPSFVE-ESSSTISFGT 305

  Fly   329 RAKTV--KNVVC-VNEELT-AEEWKRRYEKEKEKNARLKGK------VEKLEIELARWRAGETVK 383
            .||.:  |..|| ::.|.| ..:..|.....|:|.|:.|.|      :::||..:.|    :.:|
  Fly   306 CAKKIRCKPQVCKIDSETTMMRQLDRGISMLKDKLAKKKIKNESQLVLQELEGRIKR----DMLK 366

  Fly   384 AEEQINMED----------LMEASTPNLEVEAAQTAAAEAALAAQRTALANMSASVAVNEQARLA 438
            .....:::|          .:.||....:.........|.:...:.:.|.|:...:.  ::..:|
  Fly   367 IVSSASLDDYRLQKRRRTWTLTASGSEGDAPVLALPEPEESRLPRPSKLTNLPKPLF--QRRGIA 429

  Fly   439 TECERLYQQLDDK---DEEINQQSQYAEQLKEQVMEQEELIANARREYETL------QSEMARIQ 494
            .:.:.:.:.|.:|   .:.::.....|:||..:...:...:..:::..|::      |:|::.:.
  Fly   430 PKAKGICKTLKEKRLQTDNMDTMPGRAKQLGRETASRIPSVMMSKKYQESVPNCDAPQTEISALT 494

  Fly   495 QENESAK-------EEVKEVLQALEEL------AVNYDQKSQEIDNKNKDI-DALNEELQQKQSV 545
            ..|:.||       |:||.:.:.:|.|      |||..::.:....|:|.: :.|...:.:|.|.
  Fly   495 ASNQVAKETIEKYEEQVKRLKETIERLEMENGKAVNLGEQFETHKAKSKQMEEELLSSISEKDST 559

  Fly   546 FNAASTELQQL-KDMSSHQK---------------KRITEMLTNLLRDLGEVGQAIAPGESSI-- 592
            ..:....|::| :|:..:.|               :||......|.|.|   ..|.|.|..|:
  Fly   560 IVSLQQSLEELSRDVLRNSKEDQMRSMCPELESSCERICNKCLELERLL---PLASASGLDSVAC 621

  Fly   593 --DLKMSALAGTDASKVE---EDFTMARLFISKMKTEAKNIAQRCSN------------------ 634
              |...|.:|.| ..|:|   ..|:.|...:|:..|:.|.::::.|.
  Fly   622 QFDQLRSEIAAT-RMKLESMLSTFSHASCEVSQKTTDCKRLSEQISTAHDDFGQLQEKYNNLKHK 685

  Fly   635 -------METQQADSNKKISEYEKDLGEYRLLISQHEARMKSLQESMREAENKKRTLEEQIDSLR 692
                   ::|.|.|.|....:|.:...|||.|..:.:.:.:.||:...:.:.:..||:|:::.:.
  Fly   686 WSSQKLAIDTMQVDYNTIQQKYLQLQDEYRHLELRSDEQCQQLQDENSKLQAEIGTLKERVEEIH 750

  Fly   693 EECAKL----KAAEHVSAVNAEEKQRAEELRSMFD-----------------SQMDELREAHTRQ 736
            .|..::    ...|.:...|.|.|:|..:|:..||                 .:.|.|||.|.::
  Fly   751 SELLEVPNPDTHPEDMELQNQELKKRLSKLQWEFDEIQLNYECLSNELMSTIQECDALREEHKQR 815

  Fly   737 V--SELRD--------EIAAKQHEMD-EMKDVHQKLLLAHQQM-TADYEKVR------------- 776
            .  |:|..        |.:..::|:| ::.....||..:.||: ..||...|
  Fly   816 TTNSDLESMKSSGVGTECSDPENELDTDLLQQFTKLSKSIQQIELTDYSGGRRLFIYNHAEQDQS 880

  Fly   777 -------------------QEDAE-----------------KSSELQNIILTNERRE----QARK 801
                               |.||.                 |.::.||::...:|..    |.::
  Fly   881 VPSLKLCLEPAKYLEGDGKQHDASDSVFLKGFLKCQRFQIVKINQEQNLVKEEDRMRDIIFQLKQ 945

  Fly   802 DLKGLEDTVAKELQTLHNLR-------------------KLFVQDLQQRIRKNVVNEESEEDGGS 847
            ::.|.::.:.:|.:.::|||                   |:..::||.:......|::
  Fly   946 EVDGKKNLIEEEKEVINNLRAQITSLNQIETIKNQNAKTKILCEELQTKDTVQTANKQ------- 1003

  Fly   848 LAQKQKISFLENNLDQL-TKVHKQLVRDNADLRCEL-PKLEKRLRCTMERVKALETALKEAKEGA 910
              :.|::..|:.:|..| :||            ||| .||||  :...|::..|::.:.|..|..
  Fly  1004 --ESQEVLTLKTSLAHLKSKV------------CELQKKLEK--QSEDEKISELQSDIGEISECC 1052

  Fly   911 ------MRDRKRYQYE----VDRIKEA-VRQKHLGRRGPQA-QIAKPIR 947
                  :.|...:|.|    :|:::|: |..:|......:: .:.|||:
  Fly  1053 LSMELKLADIVNWQAEELRPLDQLQESGVELQHHSTTAEESLNVEKPIQ 1101

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	128/328 (39%)
		KISc	12..340	CDD:214526	131/338 (39%)
		Apolipoprotein	595..744	CDD:279749	41/207 (20%)
cana	NP_001027247.1	KISc	8..316	CDD:214526	129/334 (39%)
		Motor_domain	8..310	CDD:277568	128/328 (39%)
		SMC_prok_B	<471..1270	CDD:274008	128/658 (19%)
		Mplasa_alph_rch	924..1647	CDD:275316	40/201 (20%)
		CENP-H	1204..>1266	CDD:283493
		CALCOCO1	<1489..1850	CDD:285171

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437992
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000669
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.840