Protein Alignment Khc and neb

DIOPT Version :9

• Sequence 1: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_476817.1
• Gene: neb / 35293
• FlyBaseID: FBgn0004374
• Length: 1121
• Species: Drosophila melanogaster
• Alignment Length: 1121
• Identity: 274/1121 - (24%)
• Similarity: 429/1121 - (38%)
• Gaps: 355/1121 - (31%)

  Fly     7 IPAEDSIKVVCRFRPLNDSEEKAGS-KFVVKFPNNVEENCI-------SIAGKVYLF--DKVF-- 59
            :..|.::.|..|.||||..|...|. ..||:...|..|..:       :.||..:.|  |:|:
  Fly   115 VSEESNMIVAVRVRPLNALECTRGQVTNVVQVHGNSNELTVQAGSSADASAGVTHFFSYDQVYYS 179

  Fly    60 -----KPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGV--IGDSV------- 110
                 |..|.|.||:...|:.::.....|||..:||||||.|||:::|.|:  :.|:.
  Fly   180 CDPERKNFACQAKVFEGTARPLIDTAFEGYNACLFAYGQTGSGKSYSMMGIEALDDAALDGGPPH 244

  Fly   111 -KQGIIPRIVNDIFNHIYAM--EVNLEFHIKVSYYEIYMDKIRDLLDV----------------- 155
             :.|||||..:::|..|.|:  :..|:..::|||:|||.:||.|||.|
  Fly   245 DEAGIIPRFCHELFRRIEAVKSQQQLQVEVEVSYFEIYNEKIHDLLSVQHAAAATGESTPIQQQQ 309

  Fly   156 --SKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLIN 218
              .:..|.|.|.....|||...:...|.|...:...:..|.|.|..|.|.||:.||||||:|.|.
  Fly   310 QQQRPALKVREHPIFGPYVVDLSAHSVDSYSALRNWLAVGNSQRATASTAMNDKSSRSHSIFNIV 374

  Fly   219 VKQENLENQKKLS----------------GKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSA 267
            :...:|.:...||                .|:.||||||||::|.:|:.|..:.|..:|||||..
  Fly   375 LNLTDLSSDDGLSSDTDSSTASSLRQTRRSKISLVDLAGSERISVSGSNGERIREGVSINKSLLT 439

  Fly   268 LGNVISALADGNK-------------THIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESE 319
            ||.||:||||..|             |.:|||:|.||.:|:|:||||::|.::...||||.:..|
  Fly   440 LGKVIAALADSRKAIANGPLGSGTPSTFVPYRESVLTWLLRENLGGNSKTVMLATISPASIHADE 504

  Fly   320 TKSTLDFGRRAKTVKNVVCVNE--------ELTAE-EWKRRYEKEKEKNARLKG----------- 364
            |.:||.:..:|:::.|.|.|||        :|.|| :..:....|.|:..||.|
  Fly   505 TLATLRYACKARSIVNRVKVNESPHDKIIRDLRAEVDRLKSLRNEYERQRRLSGNSNNPVPRKII 569

  Fly   365 ---KVEKLEIELARWRAGETVKAEEQIN------MEDLMEAS---TPNLEVEAAQTAAAEAALAA 417
               .|::.|:|..|.:..|   .|.:::      ||.|.||.   ...|.|...:..|.|.....
  Fly   570 IETSVDETEVEALRQQLAE---RERELSRAQKSWMEKLKEAEDQRKSELRVLKRRGLALELTAEQ 631

  Fly   418 QRTALANMSASVAVN--------------EQARL-----------------------ATECER-- 443
            ::..|.|::|...::              .:.||                       :.|.||
  Fly   632 KQACLVNLTADPILSGTLFYLLPQGLVRIGRGRLPGGSSSSQPDIVLDGPLVALQHCSIEHERGG 696

  Fly   444 -LY--------------QQLDDK------------------------------DEEINQQSQYAE 463
             ||              :.|.|:                              |..::.|..:.|
  Fly   697 KLYVIPGSEDFETYVNGELLKDRRQLFHGDRLVIGGSHYFRISNPFCSQRGKADHPVDFQLAHQE 761

  Fly   464 QLKEQVME-QEELIANARREYETLQSEMARIQQENESAKEEVKEVLQALEELAVNYDQKSQEIDN 527
            .|::|..: :.||.|..|       :.:.:|:||......:.:|.||.||.....|...|:.::.
  Fly   762 ILQKQEQQLRSELEAEKR-------AALTKIEQERAQHARDFEERLQCLELEQFKYKCNSEMLET 819

  Fly   528 KNKDIDALNEELQQKQSVF---NAASTELQQLKDMSSHQKKRITEMLTNLLRDLGEVGQAIAPGE 589
            :.:   ||....||:.:..   :|.||..|:                :.:|.|:..:  .:.|.|
  Fly   820 ERQ---ALALAQQQEHTPLRHEDAVSTPAQK----------------STILEDIQRI--MLNPSE 863

  Fly   590 SSIDLKMSALAGTDASKVEEDFTMARLFISKMKTEAKNIAQRCSNM-------ETQQADSNKKIS 647
            .|                          :.|.:...|...|||..:       :||..|
  Fly   864 ES--------------------------LHKTQLMVKEATQRCRQLDLPLEFRQTQTPD------ 896

  Fly   648 EYEKDLGEYR--LLISQHEARMKSLQESMREAENKKRTLEEQIDSLREECAKLKAAEHVSAVNAE 710
                :.|..|  :||...:..:|        ||.....|...:|.:|:.      ||....:||.
  Fly   897 ----EFGLLRTVILILDKQRGLK--------AEWPTARLGVWLDLVRDN------AEQQEKLNAT 943

  Fly   711 EKQRAEELR-SMFDSQMDE-LREAHTRQVSELRDEIAAKQHEMDEMKDV-----HQKLLLAH--- 765
            ...::.|:. ...|:.::| |.:.|......|         .:..||||     .::||.|.
  Fly   944 TIFQSVEVDWEPLDADLNETLSDTHNSSRIAL---------NLSAMKDVLLNKPLKRLLNASSSK 999

  Fly   766 -------------QQMTADYEKVRQEDAEKSSELQNIILTNERREQARKDLKGLEDTVAKELQTL 817
                         .|:....:::...|.|:..|.|:...|                .|.:|||
  Fly  1000 SNTPRQTSTPSPGSQLVHFTKRLLTYDPEEIPESQSSFTT----------------LVQQELQ-- 1046

  Fly   818 HNLRKLFVQDLQQRIRKN----VVNEESEEDGGSLAQKQKISFLE--NNLDQ-LTKVHKQLVRDN 875
                  .:|...||:|::    ::..|:.:|.|.||    :|..|  ..:|. |..:|..|.|..
  Fly  1047 ------IMQRSAQRLRRHCEAALLERENHQDNGVLA----VSLQEALARMDTVLNGMHTSLARAE 1101

  Fly   876 ADLRCELP-KLEKRLR 890
            |......| |.:|.:|
  Fly  1102 ATACVTSPTKTQKAVR 1117

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	136/399 (34%)
		KISc	12..340	CDD:214526	137/404 (34%)
		Apolipoprotein	595..744	CDD:279749	28/159 (18%)
neb	NP_476817.1	KISc_KIF1A_KIF1B	119..525	CDD:276816	137/405 (34%)
		KISc	120..525	CDD:214526	137/404 (34%)
		Kinesin_assoc	524..657	CDD:292801	29/135 (21%)
		FHA	634..740	CDD:238017	12/105 (11%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437988
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	3	2.940