Protein Alignment Khc and CG14535

DIOPT Version :9

• Sequence 1: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001285726.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Alignment Length: 1048
• Identity: 186/1048 - (17%)
• Similarity: 343/1048 - (32%)
• Gaps: 327/1048 - (31%)

  Fly    38 PNNVEENCISIAG-KVYLFDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHT 101
            |...:|....:|. |::.||.:|.....|..|...|...::..||.|.:|.:.|.|..::|:..|
  Fly    87 PQAAQERAPMVAAPKMFAFDNLFTGEDKQSDVCASALSEVIPAVLEGSDGCLLAMGYPATGQAQT 151

  Fly   102 MEGVIGD------------SVKQGIIPRIVNDIFNHIY--AMEVNLEFHIKVSYYEIYMDK---- 148
            :.|.:|.            :...|..|..:..::..|.  ..:....|.::||...:...|
  Fly   152 VLGELGGGSGSGSASGSGVACSLGAAPCAIAWLYKGIQERRQKSGARFSVRVSAVGVSATKPDAL 216

  Fly   149 IRDLLDVSKVNLSVHEDKN-----RVPYVKGATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHS 208
            .:|||    ::.:...|.:     |..::.|.||....:.|.....::...:.|..:..:....|
  Fly   217 SQDLL----ISHAAESDDSPGIYLRDDFLGGPTELRAPTAERAALFLDSALAGRLKSSGSTASGS 277

  Fly   209 S------RSHSVFLINVKQENLENQKKLSG---KLYLVDLAGSEKVSKTGAEGTVLDEAKNINKS 264
            |      .|..:|.::|.|.:|..:..::|   :|:::||.|...              :|....
  Fly   278 SGCAAPLESALIFTLHVYQYSLSRKGGVAGGRSRLHIIDLGGCAN--------------RNGGLP 328

  Fly   265 LSALGNVISALADGNKTHIPYRDSKLTRILQESLGG-NARTTIVICCSPASFNESETKSTLDFGR 328
            ||.:||::.|:..|.: |.|::|..||.:|::.|.. .....||....|.. :..:..||:....
  Fly   329 LSGIGNILLAILSGQR-HPPHKDHPLTPLLKDCLAPITCHVAIVAHVRPEQ-SYQDALSTIQIAS 391

  Fly   329 RAKTVKNVVCVNEELTAEEWKRRYEKEKEKNARLKGKVE-KLEIELARWRAG------------- 379
            |...::                          |.|.:|. .|.:.||:...|
  Fly   392 RIHRLR--------------------------RRKHRVPMPLAVGLAQGLGGNGSSAGSGADPSS 430

  Fly   380 ETVKAEEQINM---EDLMEASTP-----------------------NLEVEAAQTAA-----AEA 413
            ..:.|:..|.|   :|..:...|                       .||...:::|:     .:.
  Fly   431 SEISADTVIYMGPNDDATDGEHPPVYLPSLTAGDNRGVMSKALKGSGLEKPPSKSASNSPMMMKK 495

  Fly   414 ALAAQRTALANMSASVAVNEQARLATECERLYQQLDDKDEEINQQSQYAEQLKEQVMEQEELIAN 478
            |:||::......|.:.::..||. |..|         ....|..:....:.:...:.....:::.
  Fly   496 AMAAEKAKKLPGSHTGSLKRQAG-AGAC---------SSPMIPHEQPQIQAMGSPIPIPRHMVSK 550

  Fly   479 A-----------RREY-----ETLQSEMARIQQEN-----ESAKEEVKEVLQALEELAVNYDQKS 522
            .           ||.:     |.|::.|.:|.:|.     ..::.:|.|....:.|  ||:.::.
  Fly   551 GSMVPSPKGSPMRRAHPGAALEQLEAGMRKITEEQWIDGPRVSRAKVAEARHLMRE--VNHVKQC 613

  Fly   523 QEIDNKNKDIDALNEELQQKQSVFN---AASTELQQLKDMSSHQKKRITEMLTNLLRDLGEVGQA 584
            :..      :|....:..:..:..|   |..::.|....|.:|:|..|.:.:.|         |.
  Fly   614 ETW------VDGPKSQSCRSLTACNLPAAGGSQTQGYGFMDAHKKTMIRQWVEN---------QT 663

  Fly   585 IAPGESSIDLKMSALAGTDASKVEEDFTMARLFISKMKTEAKNIAQRCSNMETQQADSNKKISEY 649
            ....:|::....|.             |.....:|::|.::.::..|.:.......|.|:...|.
  Fly   664 TQVFQSTVSASNSP-------------TALHWKLSQLKQKSLDLPDRPAFNPEPSLDLNQPCFES 715

  Fly   650 ----------------------------------EKDLGEYRL--LISQHEARMKSLQESMREAE 678
                                              .:|:.:..|  ::|:|.:|     |.:.|||
  Fly   716 LPLLDPAPPDGDEDEDSGPSEVPPALPLLDDPLGSRDISQDNLHRMLSRHVSR-----EQLHEAE 775

  Fly   679 -----------NKKRTLEEQIDSLREECAK--------------LKAAEH------VSAVN---A 709
                       ..:|:::..:....||.|:              |.|..|      ||:.|   .
  Fly   776 LVASRASSSHHPSQRSIDCGLQVTEEEIARTMSRDRDHDPSAHPLSALSHCDNISFVSSFNMACE 840

  Fly   710 EEKQRAEELRSMFDSQMDELREAHTRQVSE---------LRDEIAAKQHEMDEMKDVHQKLLLAH 765
            ...:..|..|..|| |:..|.|..|.|::.         .|.:|.:...|.....:|.|..:.:.
  Fly   841 SFSECGERARQQFD-QLARLHEIFTSQLAMAEVTPSAALFRTDIGSVFSEPVYHFNVGQSSVCSE 904

  Fly   766 --QQMTA----------------------------DYEKVRQEDAEKSSELQNIILTNERR---- 796
              .::|.                            ||..:||.|......||.    .|:|
  Fly   905 PAYRLTPSPPKQPSHSPSQGSLPSLNGIMEIAGMDDYALLRQPDGASDPNLQK----GEKRFTPQ 965

  Fly   797 -----EQARKDL-----KG--LEDTVAKELQTLHNLRKLFVQDLQQRIRKNVVNE--ESEEDGGS 847
                 |...|.:     ||  |||...| |..:.|:..|..|.....:..|..:|  :|..|..|
  Fly   966 HDDICELDEKSMAAAVGKGNSLEDAQHK-LNEITNILPLAAQSRLPLLPLNTSSEAYDSGHDSNS 1029

  Fly   848 LAQKQKIS 855
            ..:..|.|
  Fly  1030 TPRTSKHS 1037

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	69/328 (21%)
		KISc	12..340	CDD:214526	69/335 (21%)
		Apolipoprotein	595..744	CDD:279749	37/227 (16%)
CG14535	NP_001285726.1	Motor_domain	44..394	CDD:277568	69/326 (21%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR24115
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	1	1.100