Protein Alignment Khc and Klp10A

DIOPT Version :10

• Sequence 1: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_572687.1
• Gene: Klp10A / 32049
• FlyBaseID: FBgn0030268
• Length: 805
• Species: Drosophila melanogaster
• Alignment Length: 612
• Identity: 165/612 - (26%)
• Similarity: 253/612 - (41%)
• Gaps: 141/612 - (23%)

  Fly    10 EDSIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYL-------------------- 54
            :..|.|..|.||::..|           .|..|.:.||:..|..|
  Fly   276 DHQITVCVRKRPISRKE-----------VNRKEIDVISVPRKDMLIVHEPRSKVDLTKFLENHKF 329

  Fly    55 -FDKVFKPNASQEKVYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSV---KQGII 115
             ||..|........||...||.:|..:..|...|.||||||.|||||||.|.....|   |.||.
  Fly   330 RFDYAFNDTCDNAMVYKYTAKPLVKTIFEGGMATCFAYGQTGSGKTHTMGGEFNGKVQDCKNGIY 394

  Fly   116 PRIVNDIFNHIYAMEVNLEFH------IKVSYYEIYMDKIRDLLDVSKVNLSVHEDKNRVPYVKG 174
            .....|:|     :.:|:..:      :..|::|||..|:.|||. .|..|.|.||..:...|.|
  Fly   395 AMAAKDVF-----VTLNMPRYRAMNLVVSASFFEIYSGKVFDLLS-DKQKLRVLEDGKQQVQVVG 453

  Fly   175 ATERFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKLSGKLYLVDL 239
            .||:.|...|:|.::|:.|.:.|....|:.|.:|||||:||.|.::.   :...|:.||...:||
  Fly   454 LTEKVVDGVEEVLKLIQHGNAARTSGQTSANSNSSRSHAVFQIVLRP---QGSTKIHGKFSFIDL 515

  Fly   240 AGSEK-VSKTGAEGTVLDEAKNINKSLSALGNVISALADGNKTHIPYRDSKLTRILQES-LGGNA 302
            ||:|: |..:.|:.....|...|||||.||...|.||.. ...|:|:|.||||::|::| :|..:
  Fly   516 AGNERGVDTSSADRQTRMEGAEINKSLLALKECIRALGK-QSAHLPFRVSKLTQVLRDSFIGEKS 579

  Fly   303 RTTIVICCSPASFNESETKSTLDFGRRAK--TVKNV--VCVNEELTAEEWKRRYEKEKEKNARLK 363
            :|.::...||...:...|.:||.:..|.|  .||::  ||..
  Fly   580 KTCMIAMISPGLSSCEHTLNTLRYADRVKELVVKDIVEVCPG----------------------- 621

  Fly   364 GKVEKLEIELARWRAGETVKAEEQINM-EDLMEASTPNLEVEAAQTAAAEAALAAQRTALA---- 423
            |..|.:||        ...:.||::|| ........||....|:|:....|..:....|:.
  Fly   622 GDTEPIEI--------TDDEEEEELNMVHPHSHQLHPNSHAPASQSNNQRAPASHHSGAVIHNNN 678

  Fly   424 ---NMSASVAVNEQARLATECERLYQQLDDKDEEINQQSQYAEQLKEQVMEQEELIANARREYE- 484
               |.:.:....:.|.|::..|.      :..:|:..|.|..:.|:    :.||::....|...
  Fly   679 NNNNKNGNAGNMDLAMLSSLSEH------EMSDELIVQHQAIDDLQ----QTEEMVVEYHRTVNA 733

  Fly   485 TLQSEMARIQQENESAKEEVKEVLQALEELA--VNYDQKSQEIDNKNKDIDALNEELQQKQSVFN 547
            ||::.:|      ||         :||..|.  |:|||.|.               .::.:|:|:
  Fly   734 TLETFLA------ES---------KALYNLTNYVDYDQDSY---------------CKRGESMFS 768

  Fly   548 AASTELQQLKDMSSHQKKRIT--EMLT 572
            .......|.:||.:..:.::.  |||:
  Fly   769 QLLDIAIQCRDMMAEYRAKLAKEEMLS 795

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	115/356 (32%)
		Smc	<341..>807	CDD:440809	46/245 (19%)
		Khc_CBD_cc	856..925	CDD:467880
Klp10A	NP_572687.1	KISc_KIF2_like	278..608	CDD:276818	114/350 (33%)