Protein Alignment Khc and Klp3A

DIOPT Version :9

• Sequence 1: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Sequence 2: NP_001284830.1
• Gene: Klp3A / 31240
• FlyBaseID: FBgn0011606
• Length: 1212
• Species: Drosophila melanogaster
• Alignment Length: 1046
• Identity: 276/1046 - (26%)
• Similarity: 468/1046 - (44%)
• Gaps: 209/1046 - (19%)

  Fly     9 AED--SIKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIAGKVYLFDKVFKPNASQEKVYNE 71
            :||  .:.|..|.|||..||...|.:..|:...:..........:.|.::.||..:.||:.::..
  Fly     3 SEDPSCVAVALRVRPLVQSELDRGCRIAVERSADGAPQVTVNRNESYTYNYVFDIDDSQKDLFET 67

  Fly    72 AAKSIVTDVLAGYNGTIFAYGQTSSGKTHTM----EGVIGDSVKQGIIPRIVNDIFNHIYAMEVN 132
            ..::.|..:|.|||.||.|||||.||||:||    .||:.|.|  |:|||.|:|||..|..|:..
  Fly    68 CVQAKVKKLLNGYNVTILAYGQTGSGKTYTMGTAFNGVLDDHV--GVIPRAVHDIFTAIAEMQSE 130

  Fly   133 LEFHIKVSYYEIYMDKIRDLLDV---SKVNLSVHEDKNRVPYVKGATERFVSSPEDVFEVIEEGK 194
            ..|.:..|:.|:|.::..||...   .|..:.:.|.|||: .:.|.||..|:|.:.|.:.:..|.
  Fly   131 FRFAVTCSFVELYQEQFYDLFSSKTRDKATVDIREVKNRI-IMPGLTELVVTSAQQVTDHLIRGS 194

  Fly   195 SNRHIAVTNMNEHSSRSHSVFLINVKQENLENQKKL-SGKLYLVDLAGSEKVSKTGAEGTVLDEA 258
            :.|.:|.|.|||.|||||::|.:.:....|:.::.: :.:..||||||||:.|||.|.|....|.
  Fly   195 AGRAVAATAMNETSSRSHAIFTLTLVATKLDGKQSVTTSRFNLVDLAGSERCSKTLASGDRFKEG 259

  Fly   259 KNINKSLSALGNVISALADGNKT-HIPYRDSKLTRILQESLGGNARTTIVICCSPASFNESETKS 322
            .||||.|.||||||:||..|... :||||.|||||:||:|||||:.|.::.|.|||.:|.:||.|
  Fly   260 VNINKGLLALGNVINALGSGQAAGYIPYRQSKLTRLLQDSLGGNSITLMIACVSPADYNVAETLS 324

  Fly   323 TLDFGRRAKTVKNVVCVNEELTAEEWKRRYEKEKEKNARLKGKVEKLEIELARWRAGETVKAEEQ 387
            ||.:..||..:||...||.:..|.|..           .||..::||.:||.   :|..:.:
  Fly   325 TLRYADRALQIKNKPVVNLDPHAAEVN-----------MLKDVIQKLRVELL---SGGKMSS--- 372

  Fly   388 INMEDLMEASTPNLEVEAAQTAA--AEAALAAQRTALANMSASVAVNEQARLATECERLYQQ--- 447
                .|:.|      |.||...|  .|.:||.   ::||.:....:.||.|...:..|..||
  Fly   373 ----SLISA------VGAAGLGAIPCEESLAG---SMANAAEIQRLKEQVRTLQDRNRKLQQELH 424

  Fly   448 -----LDDKDEEINQQSQYAEQLKEQVMEQEELI---------------ANARREYETLQS---- 488
                 |.:|:...:...|..::|:..|.|.:..:               .|..|::..|.:
  Fly   425 QSLLDLTEKEMRAHIAEQAHDKLRSHVSELKNKLDQREQAQFGNENTNGDNEMRDFSLLVNRVHV 489

  Fly   489 EMARIQQE--------------------NESAKEEVKEVLQALEELAVNYDQKSQ----EIDNKN 529
            |:.|.|:|                    .||..:||.|:|.:..|   .|..|..    |:.|.|
  Fly   490 ELQRTQEELESQGHESRQRLSSRSHTEGGESGGDEVHEMLHSHSE---EYTNKQMNFAGELRNIN 551

  Fly   530 KDID---ALNEELQQKQSVFNAASTEL------QQLKDMSSHQKKRITEMLTNL-LRDLG----- 579
            :.:|   .|:|.:.:..|..::...::      |::.|:.: :::.:.:.|.|: .:|:.
  Fly   552 RQLDLKQELHERIMRNFSRLDSDDEDVKLRLCNQKIDDLEA-ERRDLMDQLRNIKSKDISAKLAE 615

  Fly   580 EVGQAIAPGESSI-DLKMSALAGTDASKVEEDFTMARLFISKMKTEAKNIAQRCSNMETQQADSN 643
            |..:.:...|..| ||:...:...:..|:.:   ..|..|..:.||.:.:.:....:.......:
  Fly   616 ERRKRLQLLEQEISDLRRKLITQANLLKIRD---KEREKIQNLSTEIRTMKESKVKLIRAMRGES 677

  Fly   644 KKISEY----EKDLGEYRLLISQHEARMKS---LQESMREAENK--KRTLEEQI-------DSLR 692
            :|..::    ||:|.:    :...:.:|:|   .|:::...:.:  ||..||.:       |:|
  Fly   678 EKFRQWKMVREKELTQ----LKSKDRKMQSEIVRQQTLHSKQRQVLKRKCEEALAANKRLKDAL- 737

  Fly   693 EECAKLKAAEHVSAVNAEEKQRAEELRSMFDSQMDELREAHTRQVSELRDEIAAKQHEMDEMKD- 756
            |..|..:|..|....|......:....:..||.:|       |::..:...|.| :|.::::.:
  Fly   738 ERQASAQAQRHKYKDNGGSAAGSSNANAKTDSWVD-------RELEIILSLIDA-EHSLEQLMED 794

  Fly   757 ---VHQKLLLAHQQMTAD----YEKVR-----QEDAE----KSSELQNIILTNERREQARKDLKG 805
               ::....|..|:.|:|    .|:.|     :|:.|    :.|:||..:...:...:.|...:|
  Fly   795 RAVINNHYHLLQQEKTSDPAEAAEQARILASLEEELEMRNAQISDLQQKVCPTDLDSRIRSLAEG 859

  Fly   806 LED-----TVAKE-LQTLHNLRKLFVQDLQQR------IRKNVVNEESEEDGGS----------- 847
            ::.     ||:|: |:||...|:|....|.::      :|..:::.:.:||..|
  Fly   860 VQSLGESRTVSKQLLKTLVQQRRLQASSLNEQRTTLDELRAQLLDAQQQEDAASKRLRLLQSQHE 924

  Fly   848 ---LAQ----KQKISFLENNLD-------------QLTKVHKQLVRDNADLRCELPKLEKRLRCT 892
               |||    ::|:|.|....:             |..::.::|:.....|:.||.||..:.:..
  Fly   925 EQMLAQQRAYEEKVSVLIRTANQRWAEARSPAEDQQRNQILEELLSSREALQQELDKLRAKNKSK 989

  Fly   893 MERVKA 898
            .:.||:
  Fly   990 SKAVKS 995

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	136/333 (41%)
		KISc	12..340	CDD:214526	136/336 (40%)
		Apolipoprotein	595..744	CDD:279749	27/164 (16%)
Klp3A	NP_001284830.1	KISc_KIF4	7..336	CDD:276823	134/331 (40%)
		Kinesin	14..335	CDD:278646	133/323 (41%)
		Smc	<396..>994	CDD:224117	116/617 (19%)
		FlaC	522..633	CDD:225888	24/114 (21%)
		TCR	1075..1110	CDD:281618

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45437981
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840