| Sequence 1: | NP_476590.1 | Gene: | Khc / 36810 | FlyBaseID: | FBgn0001308 | Length: | 975 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001239029.1 | Gene: | KIF21B / 23046 | HGNCID: | 29442 | Length: | 1637 | Species: | Homo sapiens |
| Alignment Length: | 1119 | Identity: | 283/1119 - (25%) |
|---|---|---|---|
| Similarity: | 473/1119 - (42%) | Gaps: | 283/1119 - (25%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 13 IKVVCRFRPLNDSEEKAGSKFVVKFPNNVEENCISIA----------GKVYLFDKVFKPNASQEK 67
Fly 68 VYNEAAKSIVTDVLAGYNGTIFAYGQTSSGKTHTMEGVIGDSV----KQGIIPRIVNDIFNHI-- 126
Fly 127 ---YAMEVNL---EFHIKVSYYEIYMDKIRDLLDVS--------KVNLSVHEDKNRVPYVKGATE 177
Fly 178 RFVSSPEDVFEVIEEGKSNRHIAVTNMNEHSSRSHSVFLINV------KQENLENQ--------- 227
Fly 228 ------KKLSGKLYLVDLAGSEKVSKTGAEGTVLDEAKNINKSLSALGNVISALADGNK--THIP 284
Fly 285 YRDSKLTRILQESLGGNARTTIVICCSPASFNESETKSTLDFGRRAKTVKNVVCVNEELTAEEWK 349
Fly 350 RRYEKEKEKNARLKGKVEKLEIELARWRAGETVKAEE------QINMEDLM---EASTPNLEVEA 405
Fly 406 AQTA------------AAEAALAAQRTALAN--------------------MSASVAVNEQAR-- 436
Fly 437 LATECERL-----------------YQQLDDKDEEINQQSQYAEQLKEQVMEQEELIANARR--- 481
Fly 482 EYETLQSEMARIQQEN------ESAKEEVKEVLQA----------------LEELAVNYDQKSQE 524
Fly 525 ID-NKNKDIDALNEELQQKQSVFNAASTELQQLKDMSSHQKKRITEMLTNLLRDLGEVGQAIAPG 588
Fly 589 ESSIDLKMSALAGTDASKVEEDFTMARLFISKMKTEAKNIAQRCSNMETQQADSNKKISEYEKDL 653
Fly 654 GEYRLLISQHEARMKSLQESMREAENKKRTLEEQIDSLREECAKLKAAE-----HVSAVNAEEKQ 713
Fly 714 RAEELRSMFDSQMDELREAHTRQVSELRDEIAAKQHEMDEMKDVHQKLLLAHQQMTADYEKVRQE 778
Fly 779 DAEKSSELQNIILTNERR----------------EQARKDL--KGLEDTVAK------------- 812
Fly 813 -----ELQTLHNL-----------RKLF-VQDLQQRIRKNVVNEESEEDGGSLAQKQKISFLENN 860
Fly 861 LD--------------QLTKVHKQLVRDNADL-----RCELPK----LEKRLRCTMERVKALETA 902
Fly 903 LKEAK----EGAMR 912 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Khc | NP_476590.1 | KISc_KHC_KIF5 | 10..333 | CDD:276820 | 132/372 (35%) |
| KISc | 12..340 | CDD:214526 | 135/379 (36%) | ||
| Apolipoprotein | 595..744 | CDD:279749 | 32/153 (21%) | ||
| KIF21B | NP_001239029.1 | KISc_KIF4 | 7..371 | CDD:276823 | 132/373 (35%) |
| KISc | 9..377 | CDD:214526 | 135/379 (36%) | ||
| Interaction with TRIM3. /evidence=ECO:0000250|UniProtKB:Q9QXL1 | 400..1099 | 141/705 (20%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 509..538 | 2/28 (7%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 552..628 | 19/83 (23%) | |||
| PKK | 660..794 | CDD:289257 | 31/148 (21%) | ||
| JAKMIP_CC3 | 678..806 | CDD:292653 | 27/141 (19%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 830..865 | 3/34 (9%) | |||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 880..906 | 5/25 (20%) | |||
| Prefoldin | 954..1102 | CDD:298833 | 29/114 (25%) | ||
| Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1194..1251 | ||||
| WD40 | 1305..1613 | CDD:238121 | |||
| WD40 | 1306..>1614 | CDD:225201 | |||
| WD 1 | 1306..1343 | ||||
| WD40 repeat | 1312..1346 | CDD:293791 | |||
| WD 2 | 1346..1384 | ||||
| WD40 repeat | 1351..1387 | CDD:293791 | |||
| WD40 repeat | 1407..1450 | CDD:293791 | |||
| WD 3 | 1410..1448 | ||||
| WD 4 | 1451..1493 | ||||
| WD40 repeat | 1456..1500 | CDD:293791 | |||
| WD 5 | 1502..1539 | ||||
| WD40 repeat | 1509..1541 | CDD:293791 | |||
| WD 6 | 1543..1582 | ||||
| WD40 repeat | 1548..1572 | CDD:293791 | |||
| WD 7 | 1585..1622 | ||||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 0 | 0.000 | Not matched by this tool. | |||
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 1 | 0.910 | |||||