DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment csul and SKB1

DIOPT Version :9

Sequence 1:	NP_477184.1	Gene:	csul / 36809	FlyBaseID:	FBgn0015925	Length:	610	Species:	Drosophila melanogaster
Sequence 2:	NP_194841.2	Gene:	SKB1 / 829240	AraportID:	AT4G31120	Length:	642	Species:	Arabidopsis thaliana

Alignment Length:	638	Identity:	235/638 - (36%)
Similarity:	343/638 - (53%)	Gaps:	68/638 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    19 IEKAFAN------NYNVVSTSINANMLPFEPHESDPTYPAT-------------------ILSGS 58
            :|..|:|      |:|:.:...:..:.|.    .||:|..:                   :||.|
plant    19 VETDFSNDVTHLLNFNISTGGFDYVLAPL----VDPSYRPSLVEGNGVDTQVLPVCGSDLVLSPS 79

  Fly    59 DWNSKVIFTMSD-VNVDSPNDKLREHAKEVFMRDVAWAEHLQNVGNLMVRLRGPENENLASIVLA 122
            .|:|.|:..:|. :::||.::.||..::....:::|||.||.....|:...:|....|.|..|
plant    80 QWSSHVVGKISSWIDLDSEDEVLRMDSETTLKQEIAWATHLSLQACLLPTPKGKSCANYARCV-- 142

  Fly   123 KTKDDFPSGNWFIQVPITNPELATFEHRKDATAEEVAEAESNDPWNWWNNLRMVTKHSTKVKVVI 187
               :....|...:|:.:..|.:.:.....|.|:|.:     ||.|..||:.|::.:|.:|:.|.:
plant   143 ---NQILQGLTTLQLWLRVPLVKSEGDSMDDTSEGL-----NDSWELWNSFRLLCEHDSKLSVAL 199

  Fly   188 ELNDADRPSKETVRRWLGEPIEAIIIPSSLFVRNRSNYCVLKKEWQLIVGHFISVRANIIISTNP 252
            ::. :..||:.::.||:||.:.|.|:.:..|:.|...|..|.|..|.::..|....|.::|...|
plant   200 DVL-STLPSETSLGRWMGESVRAAILSTDAFLTNARGYPCLSKRHQKLIAGFFDHAAQVVICGKP 263

  Fly   253 ---------------NDKALCQYADYV----NKLINDNCDKHMLNSYENMLEIPLQPLCDNLDTY 298
                           ....|..|.|||    .|:.:.:..:.:...|.:.|:.|||||.|||:..
plant   264 VHNLQKPLDSSSEGTEKNPLRIYLDYVAYLFQKMESLSEQERIELGYRDFLQAPLQPLMDNLEAQ 328

  Fly   299 TYEVFETDPVKYKLYQDAVQAALLDRVSAAEAKTKLTVVMLLGGGRGPLARAVFNAAELTKRKVR 363
            |||.||.|.|||..||.||:.||:|||...:|....||:|::|.|||||.||...|||.|.||::
plant   329 TYETFERDSVKYIQYQRAVEKALVDRVPDEKASELTTVLMVVGAGRGPLVRASLQAAEETDRKLK 393

  Fly   364 LYIIEKNPNAIRTLSNMVKTL-WADKDVHIFSKDMRDFSPPELADIMVSELLGSFGDNELSPECL 427
            :|.:||||||:.||.|:||.. |.|. |.|.|.|||.::.||.|||:||||||||||||||||||
plant   394 VYAVEKNPNAVVTLHNLVKMEGWEDV-VTIISCDMRFWNAPEQADILVSELLGSFGDNELSPECL 457

  Fly   428 DGALKLLKPDGISIPYKSTSYINPLMSAVLHQNVCQLLPTYPAFDYGYVSLLKNIYHIDEPQALF 492
            |||.:.|||||||||...||:|.|:.::.|:.:| :.......|:..||..|.::..:...|::|
plant   458 DGAQRFLKPDGISIPSSYTSFIQPITASKLYNDV-KAHKDLAHFETAYVVKLHSVAKLAPSQSVF 521

  Fly   493 EFVHPNRAENIDNTRCKTVSFKVNKD---CVLHGIGGYFDTHLYKDICLSINPLTHTPGMFSWFP 554
            .|.|||.:..::|.|.|.:.|.:..|   .::||..||||:.||||:.|.|.|.|.||.||||||
plant   522 TFTHPNFSTKVNNQRYKKLQFSLPSDAGSALVHGFAGYFDSVLYKDVHLGIEPTTATPNMFSWFP 586

  Fly   555 MFFATR-PRTLREGQTISIQFWRCVDATKVWYEWQVVNSPDDWEHHNTRGTGY 606
            :||..| |..:.....:.:.||||..::||||||. |:||.....|||.|..|
plant   587 IFFPLRKPVEVHPDTPLEVHFWRCCGSSKVWYEWS-VSSPTPSPMHNTNGRSY 638

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
csul	NP_477184.1	PRMT5	163..589	CDD:282971	191/449 (43%)
csul	NP_477184.1	SAMBD	165..442	CDD:293555	131/296 (44%)
SKB1	NP_194841.2	PRMT5	174..624	CDD:282971	192/458 (42%)
SKB1	NP_194841.2	SAMBD	177..472	CDD:293555	131/296 (44%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	188	1.000	Domainoid score	I967
eggNOG	1	0.900	-	-		E1_KOG0822
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4454
Inparanoid	1	1.050	383	1.000	Inparanoid score	I522
OMA	1	1.010	-	-		QHG54770
OrthoDB	1	1.010	-	-		D475852at2759
OrthoFinder	1	1.000	-	-		FOG0004858
OrthoInspector	1	1.000	-	-		oto4026
orthoMCL	1	0.900	-	-		OOG6_101720
Panther	1	1.100	-	-	LDO	PTHR10738
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X3428
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	14	13.840