Protein Alignment fidipidine and Ccdc93

DIOPT Version :9

• Sequence 1: NP_523760.1
• Gene: fidipidine / 36808
• FlyBaseID: FBgn0025519
• Length: 595
• Species: Drosophila melanogaster
• Sequence 2: NP_001020327.1
• Gene: Ccdc93 / 70829
• MGIID: 1918079
• Length: 629
• Species: Mus musculus
• Alignment Length: 624
• Identity: 248/624 - (39%)
• Similarity: 360/624 - (57%)
• Gaps: 74/624 - (11%)

  Fly    28 QVERREDSDATAKEQDTFDILVAAGYYRARIKGLSAFDKVVGGMTWCIECCDYDVDVDLLFHESL 92
            :||.|||.:...|..:..::||||||:||||||||.||||||||||||..|.:||||||||.|:.
Mouse    14 EVETREDEEQNVKLTEILELLVAAGYFRARIKGLSPFDKVVGGMTWCITTCSFDVDVDLLFQENS 78

  Fly    93 SIGQKIALVEKIVAVLIDMKCPHSLEPHQVQGLEFLAIHPVIQWLVKTSVENRAERGQRLKRFAI 157
            :|||||||.||||:||..|||||.|||||:||::|:.|.||:|||||.::|.:.|.|..::.::|
Mouse    79 TIGQKIALSEKIVSVLPRMKCPHQLEPHQIQGMDFIHIFPVVQWLVKRAIETKEEMGDYIRSYSI 143

  Fly   158 GQFHNHYQYKSDKDNLTKIRLASTNIKAIQDLYGPRRQYERQ----EAPDDDDDVSRVRLTLLEY 218
            .||...|....|.|.:.:...|...:..:.|.|.|||:|.||    |.||::   |||..|||||
Mouse   144 SQFQKTYSLPEDDDFIKRKDKAVKTVVGLSDAYKPRRKYRRQRGAEELPDEE---SRVHSTLLEY 205

  Fly   219 GDP-GPTFRSSAERKADRGPG--------------EKDELDL--EEYLRSLSLIKDDPTGTQKRI 266
            |.. |.:.:|..|:..|:...              |:|||..  |:.::||..........:.|:
Mouse   206 GRRYGFSRQSKTEKAEDKKTALAAGLSAAEKVDAHEEDELQAAEEQRIQSLMTKMTAMANEESRL 270

  Fly   267 DLDPTAR------QELQQHYAEF-----KLEMETDAQEL-KSQNQQKRLEAAKIAMEHKIRRYCK 319
            ......:      :|::|..:|:     :|..|...::| .||..|:::    |::..:|.:..|
Mouse   271 TASSVGQIVGLCSEEIKQIVSEYAGKQSELSAEESPEKLGTSQLHQRKV----ISLNKQILQKSK 331

  Fly   320 ENEQLQDAENEQKEKTKEVEDQLNTLNTELKAHKDTQD-----------KADPKLLEKIQSLLQQ 373
            ..|:||......|.|   ..|:..|| ||||.|.:..|           ||||.:|:.:::|:..
Mouse   332 HLEELQANHTSLKAK---YSDRKKTL-TELKDHGEKLDKEQAALEKLEAKADPSMLQNLRALVAM 392

  Fly   374 HEELKKSEAEFKESCRTDLANLQLQIDDLESFSA------QDAEAQAAALAG------------- 419
            :|.||..|.|||..||.::|.||.:|:.|::..|      ...|.|.|..:.
Mouse   393 NESLKSQEQEFKAHCREEMARLQQEIETLKAERAPGEKIISGGEPQGALTSTMTHNEDLDRRYNM 457

  Fly   420 EEQRLKELRLQLAKRNRGIVAIERKLDAIPDRTELAQYQRRFHELHNEMSGKHLETKQYYTLYNT 484
            |:::|.::||..|:|||.|..:.||:|.:|.|.||.|||:||.||:.::|..|.||||::|||||
Mouse   458 EKEKLYKIRLLQARRNREIAILHRKIDEVPSRAELIQYQKRFIELYRQISAVHKETKQFFTLYNT 522

  Fly   485 LNDKKRYMEKELALLNSICEAYNEGMMSPHGREDFIRQFESIVDGVKSAQDKVRHKYNEERMRRD 549
            |:|||.|:|||::|||||.|.:::.|.||..|:.|:||.|.||:|:|.::.|:..|..|.:||||
Mouse   523 LDDKKVYLEKEISLLNSIHENFSQAMASPAARDQFLRQMEQIVEGIKQSRMKMEKKKQENKMRRD 587

  Fly   550 ELNEELQSLLELQRQYALAVKQLTRECQRCEQLQLQLRS 588
            :||::...|||.||.|...||:...|.::.|.|..::::
Mouse   588 QLNDQYLELLEKQRLYFKTVKEFKEEGRKNELLLSKIKA 626

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
fidipidine	NP_523760.1	KOG2701	42..219	CDD:286803	98/180 (54%)
Ccdc93	NP_001020327.1	Sufficient for interaction with CCDC22. /evidence=ECO:0000250|UniProtKB:Q567U6	1..428		165/424 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..23		5/8 (63%)
		KOG2701	29..206	CDD:286803	98/179 (55%)
		BAR	241..426	CDD:299863	54/192 (28%)
		Sufficient for interaction with WASHC2C. /evidence=ECO:0000250|UniProtKB:Q567U6	446..629		80/181 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167836114
Domainoid	1	1.000	211	1.000	Domainoid score	I2795
eggNOG	1	0.900	-	-		E1_KOG2701
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H10393
Inparanoid	1	1.050	410	1.000	Inparanoid score	I1848
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG54367
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0004838
OrthoInspector	1	1.000	-	-		oto93451
orthoMCL	1	0.900	-	-		OOG6_104885
Panther	1	1.100	-	-	LDO	PTHR16441
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R3346
SonicParanoid	1	1.000	-	-		X4513
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	15	14.790