DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CngA and GORK

DIOPT Version :9

Sequence 1:	NP_001188960.1	Gene:	CngA / 36806	FlyBaseID:	FBgn0261612	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_001332118.1	Gene:	GORK / 833728	AraportID:	AT5G37500	Length:	842	Species:	Arabidopsis thaliana

Alignment Length:	599	Identity:	121/599 - (20%)
Similarity:	236/599 - (39%)	Gaps:	141/599 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   275 VDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLDTLVHMHEG 339
            :.|..:.:..|...:.:..:|:.:|......|:   :..|...:.||.:....:|:|.::.....
plant    58 IHPKNRWYKAWEMFILVWAIYSSLFTPMEFGFF---RGLPERLFVLDIVGQIAFLVDIVLQFFVA 119

  Fly   340 FLDQGLL------VRDAFR-LRRHYFHTKGWYLDVLSMLPTDLAY------------IWWPPETC 385
            :.|....      .|.||| |:.|:.      :|.:...|.||.|            :|
plant   120 YRDTQTYRTVYKPTRIAFRYLKSHFL------MDFIGCFPWDLIYKASGKHELVRYLLW------ 172

  Fly   386 SSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAF-RICKVVLAILVLIHWNACMYFAISY 449
                         .||.|:.::.|:|.|.|..|.....| ||.|::...:...|..||:::.::.
plant   173 -------------IRLFRVRKVVEFFQRLEKDTRINYLFTRILKLLFVEVYCTHTAACIFYYLAT 224

  Fly   450 EIGFSSD--SWV-------YNLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDV------E 499
            .:...::  :|:       |:....|...|.::|..:.|::.:|:.|:|     ..|:      |
plant   225 TLPPENEGYTWIGSLKLGDYSYENFREIDLWKRYTTALYFAIVTMATVG-----YGDIHAVNLRE 284

  Fly   500 YLFVVADFLAGVLIFATIVGNIGSMI-SNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWF 563
            .:||:......:::.|.::|||.::| ...|..|  |:::|:.:..:|..:::|.:|.:::....
plant   285 MIFVMIYVSFDMVLGAYLIGNITALIVKGSNTER--FRDKMNDLISFMNRKKLGRDLRSQITGHV 347

  Fly   564 AYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPG 628
            ...:...  ..:..:|..:|..::|:||..:::..:|:|.:|.......:..:|::|..:.|.||
plant   348 RLQYDSH--YTDTVMLQDIPASIRAKIAQLLYLPYIKKVPLFKGCSTEFINQIVIRLHEEYFLPG 410

  Fly   629 DYICRKGDVGKEMYIVKRGKLS--VVGDDGITVLAT-LGAGSVFGEVSVLEIAGNRTGNRRTANV 690
            :.|..:|:|...:|.|..|.|.  |...||.....| ||..:.||::|::            .|:
plant   411 EVITEQGNVVDHLYFVCEGLLEALVTKTDGSEESVTLLGPHTSFGDISII------------CNI 463

  Fly   691 RSLGYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRKDGLLDEQIFADSQRV--HDSIEGGI 753
                 |..|.:...:|                  |.|||    ||:|.|::...:  ||
plant   464 -----SQPFTVRVCEL------------------CHLLR----LDKQSFSNILEIYFHD------ 495

  Fly   754 EKLELSVENLNMRLARLLAEYTASQAKIKQRLAKLE----MNGGPGTWRLECEPQSRARSGRLYS 814
                          .|.:......:.:...|:.|||    ::.|.....|..:..|.|..|..|.
plant   496 --------------GRTILNNIMEEKESNDRIKKLESDIVIHIGKQEAELALKVNSAAFQGDFYQ 546

  Fly   815 LQPKRRPRSRPDAT 828
            |:...|..:.|:.|
plant   547 LKSLIRSGADPNKT 560

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	51/255 (20%)
		Ion_trans_2	<477..527	CDD:285168	13/56 (23%)
		Crp	598..>722	CDD:223736	28/126 (22%)
		CAP_ED	604..717	CDD:237999	26/115 (23%)
		CLZ	720..791	CDD:293134	15/76 (20%)
GORK	NP_001332118.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	45	1.000	Domainoid score	I4624
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910