DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CngA and KAT3

DIOPT Version :9

Sequence 1:	NP_001188960.1	Gene:	CngA / 36806	FlyBaseID:	FBgn0261612	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_194991.1	Gene:	KAT3 / 829400	AraportID:	AT4G32650	Length:	662	Species:	Arabidopsis thaliana

Alignment Length:	498	Identity:	110/498 - (22%)
Similarity:	218/498 - (43%)	Gaps:	62/498 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   279 LQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLDTLVHMHEGFLDQ 343
            |..:..|.::..||                ..|:|.....|:|.:.||.:.:|.::.....:||.
plant    96 LVGYSAWASLFELA----------------FEKAAEGALLTIDLVVDFFFAVDIILTFFVSYLDN 144

  Fly   344 G--LLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWWPPETCSSLYLPCPV-------IVRLN 399
            .  |.|.|...:.:.|..:..:.:||.|.||....|     :|.:.     .|       .:.|.
plant   145 TTYLNVTDHKLIAKRYLKSVAFVMDVASTLPIQFIY-----KTITG-----DVGRGQAFGFLNLL 199

  Fly   400 RLLRINRLWEWFDRTETATGYPNAF--RICKVVLAILVLIHWNACMYFAISYEIGFSSDSWV-YN 461
            ||.|:.|:.|.|.|.|....: |.|  |:.|::...:..||...|:.:.|:|.....:|:|: ..
plant   200 RLWRLRRVAELFKRLEKDAHF-NYFVIRVIKLLCVTIFWIHLAGCILYWIAYHYPRPTDTWIGSQ 263

  Fly   462 LNGTRNNTLQRQYIYSFYWSTLTLTTIGETPT-PENDVEYLFVVADFLAGVLIFATIVGNIGSMI 525
            :...:..::...|.||.|||.:||||:|.... ..|..|..|.:...|..:.:.:.|:|.:.:::
plant   264 VEDFKERSVWLGYTYSMYWSIVTLTTVGYGDLHAVNSREKTFNMFYMLFNIGLTSYIIGIMTNLV 328

  Fly   526 SNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEI 590
            .:..:.....::.::.:.:|.:..|:...:..:::......: ::..|.:|.||..||..:::.|
plant   329 VHGALRTFAMRSAINDILRYTSKNRLPDTMREQMLAHMQLKF-KTAELRQEEVLQDLPKAIRSSI 392

  Fly   591 AIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDD 655
            ...:....:::..:|.....|||..||.:::.:.|.|...|..:.::..:.|::..|.:.::...
plant   393 NQHLFRSIIEEAYLFKGFPEGLLVQLVSQIQAEYFPPKMEIILQNEIPTDFYVIVSGGVDIIASK 457

  Fly   656 GIT--VLATLGAGSVFGEVSVL----EIAGNRTGNRRTANVRSLGYSDLFCLAKRD-------LW 707
            |::  |||.||.||:.||:.|:    :....||  ||.:.|..:|:.....:.:.|       :.
plant   458 GVSEQVLAKLGPGSMAGEIGVVFNIPQPFTVRT--RRLSQVIRIGHHKFKEMVQSDNDVDAKMII 520

  Fly   708 ETLSDYPEARSTLTQRGCQLLRKDGLLDEQIFADSQRVHDSIE 750
            .....|.:..:...::....||  .|||:   ||:| |.::::
plant   521 ANFMTYLKGLNDELKKEIPFLR--DLLDD---ADAQ-VQETVQ 557

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	58/232 (25%)
		Ion_trans_2	<477..527	CDD:285168	15/50 (30%)
		Crp	598..>722	CDD:223736	30/136 (22%)
		CAP_ED	604..717	CDD:237999	30/125 (24%)
		CLZ	720..791	CDD:293134	9/31 (29%)
KAT3	NP_194991.1	PLN03192	51..>532	CDD:215625	101/465 (22%)
KAT3	NP_194991.1	KHA	590..661	CDD:403134
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	112	1.000	Inparanoid score	I2057
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.970