DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CngA and CNGC12

DIOPT Version :9

Sequence 1:	NP_001188960.1	Gene:	CngA / 36806	FlyBaseID:	FBgn0261612	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_001324486.1	Gene:	CNGC12 / 819253	AraportID:	AT2G46450	Length:	649	Species:	Arabidopsis thaliana

Alignment Length:	515	Identity:	106/515 - (20%)
Similarity:	197/515 - (38%)	Gaps:	121/515 - (23%)

- Green bases have known domain annotations that are detailed below.

  Fly   288 IVSLAV--LYNIIFVVGRAVFWEINKSAPAFWYTLD-----------------YLCDFIYLL--D 331
            :|:||:  |:..|.::          .:..|.:|.|                 |:...||.|  :
plant    49 VVALAIDPLFLFIPLI----------DSQRFCFTFDKTLVAVVCVIRTFIDTFYVIHIIYYLITE 103

  Fly   332 TLVHMHEGFLDQGLLVRDAFRLR-RHYFHTKGWYLDVLSMLPTDLAYIWWPPETCSSLYLPCPVI 395
            |:....:..|...::|.....|: |..||   :.:|::|:||.        |:......:|....
plant   104 TIAPRSQASLRGEIVVHSKATLKTRLLFH---FIVDIISVLPI--------PQVVVLTLIPLSAS 157

  Fly   396 VRLNRLL----------RINRLWEWFDRTETATGYPNAFRICKVVLAI-LVLIH----------- 438
            :...|:|          ||.|::..:.....|.|.....:.....|.: |.::|
plant   158 LVSERILKWIILSQYVPRIIRMYPLYKEVTRAFGTVAESKWAGAALNLFLYMLHSYVFGAFWYLS 222

  Fly   439 --------WNA-------------------------------CMYF-------AISYEIGFSSDS 457
                    |.|                               |...       :..::.|...|:
plant   223 SIERKSKCWRAACARTSDCNLTVTDLLCKRAGSDNIRFLNTSCPLIDPAQITNSTDFDFGMYIDA 287

  Fly   458 WVYNLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDV-EYLFVVADFLAGVLIFATIVGNI 521
            ....:...:.....|:::|.|:|....::.:|:.....|.. |..|.:...::|:|:||.::||:
plant   288 LKSGVLEVKPKDFPRKFVYCFWWGLRNISALGQNLETSNSAGEIFFAIIICVSGLLLFAVLIGNV 352

  Fly   522 GSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKL 586
            ...:.:......|.:.:....:::|::|.:...|:.|:.|:..|.|.::...:||.:|.:||..|
plant   353 QKYLQSSTTRVDEMEEKRRDTEKWMSYRVIPEYLKERIRRFEDYKWRETKGTEEEALLRSLPKDL 417

  Fly   587 KAEIAIQVHMDTLKQVRIFHDTEPG-LLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKL- 649
            :.|....:::|.||:|...:..:.| ||||:..::|...:....:|.|:|...:||.||.||||
plant   418 RLETKRYLYLDMLKRVPWLNIMDDGWLLEAVCDRVKSVFYLANSFIVREGHPVEEMLIVTRGKLK 482

  Fly   650 SVVGDDGITV---LATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDL 706
            |..|...:.|   ...|..|.:.||   |...|:|... .|..|.:|...:.|.|...|:
plant   483 STTGSHEMGVRNNCCDLQDGDICGE---LLFNGSRLPT-STRTVMTLTEVEGFILLPDDI 538

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	49/308 (16%)
		Ion_trans_2	<477..527	CDD:285168	12/50 (24%)
		Crp	598..>722	CDD:223736	36/114 (32%)
		CAP_ED	604..717	CDD:237999	33/108 (31%)
		CLZ	720..791	CDD:293134
CNGC12	NP_001324486.1	Ion_trans	<302..362	CDD:395416	14/59 (24%)
CNGC12	NP_001324486.1	CAP_ED	435..560	CDD:237999	33/108 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.920