DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CngA and SPIK

DIOPT Version :9

Sequence 1:	NP_001188960.1	Gene:	CngA / 36806	FlyBaseID:	FBgn0261612	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_180131.3	Gene:	SPIK / 817099	AraportID:	AT2G25600	Length:	888	Species:	Arabidopsis thaliana

Alignment Length:	445	Identity:	99/445 - (22%)
Similarity:	189/445 - (42%)	Gaps:	55/445 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly   258 ALSSEIRGS-SVLCNRLSVDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWE-------INKSAP 314
            :|.:..|.| .|:..|..|.|....:..|...:...|||..         |.       :.|..|
plant    55 SLGANNRSSRDVILPRFIVSPFDPRYRAWETFLVFLVLYTA---------WASPFEFGFLQKPRP 110

  Fly   315 AFWYTLDYLCDFIYLLDTLVHMHEGFLDQ--GLLVRDAFRLRRHYFHTKGWYL-DVLSMLPTDLA 376
            .. ..||.:.:..:.:|.::.....|||:  .|||.|..|:...|..|  |.: ||:|.
plant   111 PL-SILDNIVNGFFAVDIVLTFFVAFLDKVTYLLVDDPKRIAWRYAST--WLIFDVVST------ 166

  Fly   377 YIWWPPETCSSLY---LPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAF-RICKVVLAILVLI 437
               :|.|...||.   :....|..:.||.|:.|:...|.|.|....|...: |..|::|..|.:|
plant   167 ---FPYEIFGSLLHESIQGYGIFSMLRLWRLRRVSNCFARLEKDRKYSYFWVRCSKLLLVTLFVI 228

  Fly   438 HWNACMYFAISYE--------IGFSSDSWVYNLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPT- 493
            |..||..::|:..        :..:.::|..:....|.||       :.|||..|.:|.|....
plant   229 HCGACFLYSIAAHYPDPSKTFMALTDENWKESPIAVRYNT-------AMYWSITTFSTTGYGDIH 286

  Fly   494 PENDVEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEAR 558
            ..|..|..|::...:..:.:.|.|:||:.:::.::.....:|::.:.....:.....:...|:.:
plant   287 GVNSREMTFILFYMVFNLGLSAYIIGNMTNLVVHVTGRTRKFRDTIQAASGFGQRNNLPVRLQDQ 351

  Fly   559 VIRWFAYTW-SQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKL 622
            ::......: :.|..|.::.::.:||..:::.|:..:..:.:.::.:||.....||..||.::|.
plant   352 MVAHLCLRYRTDSEGLQQQEIIDSLPKAIRSSISHYLFYEVVDKIYLFHGISNDLLFQLVTEMKA 416

  Fly   623 QVFSPGDYICRKGDVGKEMYIVKRGKLSVVGD-DGI-TVLATLGAGSVFGEVSVL 675
            :.|.|.:.:..:.:...:.||:..|.:.::.. :|: .|::....|.|||||.||
plant   417 EYFPPKEDVILQNEAPTDFYILVTGAVDIIARVNGVEQVVSEAQRGHVFGEVGVL 471

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	58/235 (25%)
		Ion_trans_2	<477..527	CDD:285168	13/50 (26%)
		Crp	598..>722	CDD:223736	22/80 (28%)
		CAP_ED	604..717	CDD:237999	22/74 (30%)
		CLZ	720..791	CDD:293134
SPIK	NP_180131.3	PLN03192	38..888	CDD:215625	99/445 (22%)
		ANK repeat	548..574	CDD:293786
		ANK repeat	576..607	CDD:293786
		ANK repeat	609..671	CDD:293786
		ANK repeat	673..704	CDD:293786
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		mtm987
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920