DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CngA and CNGC14

DIOPT Version :9

Sequence 1:	NP_001188960.1	Gene:	CngA / 36806	FlyBaseID:	FBgn0261612	Length:	840	Species:	Drosophila melanogaster
Sequence 2:	NP_001324934.1	Gene:	CNGC14 / 816997	AraportID:	AT2G24610	Length:	741	Species:	Arabidopsis thaliana

Alignment Length:	467	Identity:	101/467 - (21%)
Similarity:	192/467 - (41%)	Gaps:	91/467 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly   323 LCDFIYLLDTLVHMHEGFLD-------QGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWW 380
            |.|..|:|..::.....::.       :|.||:|...:.|.|..: .:.:|:::.||......|:
plant   147 LADLFYVLHIVIKFRTAYVSRTSRVFGRGELVKDPKLIARRYLRS-DFIVDLIACLPLPQIVSWF 210

  Fly   381 ---------PPETCSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPN-------AFRICKV 429
                     ...|.::|.|    ||.:..:.|:..::........|||...       |:.:.:.
plant   211 ILPSIRSSHSDHTTNALVL----IVLVQYIPRLYLIFPLSAEIIKATGVVTTTAWAGAAYNLLQY 271

  Fly   430 VLAILVL--------------------------------------IH------W-NACMYFA--- 446
            :||..:|                                      :|      | |..:.|:
plant   272 MLASHILGSAWYLLSIERQATCWKAECHKESVPLQCVTDFFDCGTLHRDDRNNWQNTTVVFSNCD 336

  Fly   447 ----ISYEIGFSSDSWVYNLNGTRNNTLQRQYIYSFYWSTLTLTTIGET-PTPENDVEYLFVVAD 506
                |.:..|..:|:...|:   .::....:|:|..::....|::.|:. .|..:.:|.:|.:..
plant   337 PSNNIQFTFGIFADALTKNV---VSSPFLEKYLYCLWFGLQNLSSYGQNLSTSTSVLETMFAILV 398

  Fly   507 FLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSG 571
            .:.|:::||.::||:.:.:.::.|...|::.:....:::|..|.:...|..||.|:..|.|..:.
plant   399 AIFGLVLFALLIGNMQTYLQSITVRLEEWRLKRRDTEEWMGHRLLPQNLRERVRRFVQYKWLATR 463

  Fly   572 ALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGD 636
            .:|||.:|.:||..|:.:|...:.:|.:::|.:|...:..||:|:..:|...:.:.|:||.|:||
plant   464 GVDEETILHSLPADLRRDIQRHLCLDLVRRVPLFAQMDDQLLDAICERLASSLSTQGNYIVREGD 528

  Fly   637 VGKEMYIVKRGKLSVV----GDDGITVLATLGAGSVFG-EVSVLEIAGNRTGN--RRTANVRSLG 694
            ...||..:.||||...    |..|.....||..|...| |:....:....|.|  ..|..||:|.
plant   529 PVTEMLFIIRGKLESSTTNGGRTGFFNSITLRPGDFCGEELLAWALLPKSTVNLPSSTRTVRALE 593

  Fly   695 YSDLFCLAKRDL 706
            ..:.|.|...||
plant   594 EVEAFALQAGDL 605

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	47/281 (17%)
		Ion_trans_2	<477..527	CDD:285168	10/50 (20%)
		Crp	598..>722	CDD:223736	35/116 (30%)
		CAP_ED	604..717	CDD:237999	34/110 (31%)
		CLZ	720..791	CDD:293134
CNGC14	NP_001324934.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	53	1.000	Domainoid score	I4197
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.920