Protein Alignment CngA and cnga1b

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_701036.5
• Gene: cnga1b / 572249
• ZFINID: ZDB-GENE-110408-39
• Length: 639
• Species: Danio rerio
• Alignment Length: 658
• Identity: 299/658 - (45%)
• Similarity: 412/658 - (62%)
• Gaps: 66/658 - (10%)

  Fly   141 EEEDDDDVDEDDDDEFGA-----SVCEDNPEEAIARADHDTQQKQHYQPNASDSSYVENGRKLIQ 200
            |:...:||.|:...:.||     :...:|.||...:...:.::|:..:.........|  :|..|
Zfish    19 EQVTMEDVIENKRPDAGALFNNTNNSNNNEEEDKKKKKKEKKEKKEKKEKKEKKEKKE--KKKEQ 81

  Fly   201 EPSKRSKPSALRRTLQALRQRLTKRNRPKPPDWFLEKFSNTTNTDKIGKGCPAMEDAALSSEIRG 265
            |..::.|    .:..:..:::..::.:.:||                             .||.
Zfish    82 EEKEKEK----EKEKEKEKEKEKEKEKKEPP-----------------------------KEIE- 112

  Fly   266 SSVLCNRLSVDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLL 330
                    .|||....:|.||.:::..|:||.||::.||.|.|:.......|:.||||.|.:|||
Zfish   113 --------VVDPAGNMYYNWLFVITCPVMYNWIFIIARACFEELQGDYLILWFFLDYLSDAVYLL 169

  Fly   331 DTLVHMHEGFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWWP---PETCSSLYLPC 392
            |.:.....|:|:|||||:|..:||..|..:..:.||:.||:|||:.|:::.   ||
Zfish   170 DMVFRTRTGYLEQGLLVKDQKKLRDRYTDSLQFRLDLASMVPTDVFYLYFGMNYPE--------- 225

  Fly   393 PVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFSSDS 457
               :|:|:|||||||:|:|.||||.|.:||.|||..:|:.|:::||||||||::.|..|||.||:
Zfish   226 ---IRMNKLLRINRLFEFFQRTETRTNFPNVFRISNLVMYIVIIIHWNACMYYSFSKAIGFGSDA 287

  Fly   458 WVY-NLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDVEYLFVVADFLAGVLIFATIVGNI 521
            :|| :.:......|.|:|.||.||||||||||||||.|..:.||.|||.|||.|||||||||||:
Zfish   288 FVYPDPSDPEFGRLVRKYAYSMYWSTLTLTTIGETPPPVENSEYFFVVTDFLVGVLIFATIVGNV 352

  Fly   522 GSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKL 586
            ||||:|.|.||.:||.|:|.:||||:||:|..:||.|||:||.|.|:...|:||..||..|||||
Zfish   353 GSMITNANAARADFQARIDAIKQYMSFRKVTKDLEKRVIKWFDYLWTNKKAVDEREVLKYLPDKL 417

  Fly   587 KAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSV 651
            :|||||.||:||||:||||.|.|.|||..|||||:.||:|||||||:|||:|:||||:|.|||:|
Zfish   418 RAEIAINVHLDTLKKVRIFADCEAGLLVELVLKLQPQVYSPGDYICKKGDIGREMYIIKEGKLAV 482

  Fly   652 VGDDGITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEA 716
            |.|||||....|..||.|||:|:|.|.|:|.|||||||:||:||||||||:|.||.|.|::||:|
Zfish   483 VADDGITQFVVLSDGSYFGEISILNIKGSRAGNRRTANIRSIGYSDLFCLSKDDLMEALTEYPDA 547

  Fly   717 RSTLTQRGCQLLRKDGLLDEQIFADSQRVHDSIEGGIEKLELSVENLNMRLARLLAEYTASQAKI 781
            ::.|.::|.|:|.||.|||.::........| :|..::|:...:|:|..|.||||||..|:|.|:
Zfish   548 KAMLEEKGRQILMKDNLLDLELAKQGPDPKD-MEEKVQKIGGVLEDLQTRFARLLAEQEAAQGKL 611

  Fly   782 KQRLAKLE 789
            |:|:.|||
Zfish   612 KKRVTKLE 619

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	126/250 (50%)
		CAP_ED	604..717	CDD:237999	75/112 (67%)
		CLZ	720..790	CDD:465160	29/70 (41%)
cnga1b	XP_701036.5	None