Protein Alignment CngA and kcnh6b

DIOPT Version :9

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_021328182.1
• Gene: kcnh6b / 570070
• ZFINID: ZDB-GENE-121214-55
• Length: 893
• Species: Danio rerio
• Alignment Length: 550
• Identity: 135/550 - (24%)
• Similarity: 247/550 - (44%)
• Gaps: 85/550 - (15%)

  Fly   204 KRSKPSALRRTLQALRQRLTKRNRPKPPDWFLEKFSNTTN--TDKIGKGCPAMEDAALSSEIRGS 266
            :||.||.....::.:..::.:|.:            |.|.  |..:..|...:.:..|.:.
Zfish    39 RRSNPSTAHSNIELVTPKVKERTQ------------NVTEKVTQVLSLGADVLPEYKLQAP---- 87

  Fly   267 SVLCNRLSVDPTLQSHYR-----WLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLC-- 324
                   .|...:..||.     |..::.|.|||..:|....|.|. :|:.......|..|.|
Zfish    88 -------DVHKWIMLHYSPFKAIWDWVILLLVLYTAVFTPFSAAFL-LNELEDERRQTCGYTCNP 144

  Fly   325 --------DFIYLLDTLVHMHEGFLDQG-LLVRDAFRLRRHYFHTKGW-YLDVLSMLPTD-LAYI 378
                    |.:::.|.::.....:::.. .:|....|:..||.  ||| ::|:::.:|.| |.:.
Zfish   145 LNVVDVIVDVLFIADIVITFRTTYVNHNDEVVTHPKRIAIHYI--KGWFFIDMVAAIPFDLLIFR 207

  Fly   379 WWPPETCSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAIL-----VLIH 438
            ....||.::|.    .:::..||||:.|:....||   .:.|..|      ||.:|     ::.|
Zfish   208 SGSDETTATLI----GLLKTARLLRLVRVARKLDR---YSEYGAA------VLFLLMCTFGLIAH 259

  Fly   439 WNACMYFAISY-EIGFSSDSWVYNLN---GTRNN--------TLQRQYIYSFYWSTLTLTTIG-E 490
            |.||:::||.: |..:....|:.||.   |.|.|        ::|.:||.:.|::..:||::| .
Zfish   260 WLACIWYAIGHVERPYMKTGWLDNLADQLGKRYNDSDASSGPSIQDKYITALYFTFSSLTSVGFG 324

  Fly   491 TPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHEL 555
            ..:|..:.|.:|.:.....|.|::|:|.||:.::|..:......:..:|..||:::.|.::...|
Zfish   325 NVSPNTNSEKMFSICVMFIGSLMYASIFGNVSAIIQRLYSGTTRYHTQMLRVKEFIRFHQIPGGL 389

  Fly   556 EARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKL 620
            ..|:..:|.:.||.:..:|...||...|:.|:|:|.:.::...|:..::|.......|.||.::.
Zfish   390 RQRLEEYFQHAWSYTNGIDMNAVLKGFPECLQADICLHLNRSLLQNCKVFRGASKACLRALAVRF 454

  Fly   621 KLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGE-VSVLEIAGNRTGN 684
            :.....|||.:..:||:.:.::.:.||.:.|...:  .|||.||...|||| |::....|:
Zfish   455 RSTHSPPGDALYHQGDMLRALHFISRGSIQVSQHN--IVLAILGKNDVFGEPVNLYAEPGH---- 513

  Fly   685 RRTANVRSLGYSDLFCLAKRDLWETLSDYP 714
             ..|:|.:|.|.||..:.:.||.|.|..||
Zfish   514 -SNADVTALTYCDLHRIRRDDLLEVLDMYP 542

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	62/250 (25%)
		Ion_trans_2	<477..527	CDD:285168	14/50 (28%)
		Crp	598..>722	CDD:223736	35/117 (30%)
		CAP_ED	604..717	CDD:237999	34/111 (31%)
		CLZ	720..791	CDD:293134
kcnh6b	XP_021328182.1	Ion_trans	103..364	CDD:306908	70/276 (25%)
		CAP_ED	438..549	CDD:237999	34/111 (31%)
		PAT1	<681..>831	CDD:330585

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.910