Protein Alignment CngA and cnga3a

DIOPT Version :9

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_005166141.1
• Gene: cnga3a / 567242
• ZFINID: ZDB-GENE-090611-2
• Length: 765
• Species: Danio rerio
• Alignment Length: 658
• Identity: 301/658 - (45%)
• Similarity: 408/658 - (62%)
• Gaps: 70/658 - (10%)

  Fly   138 DEDEEEDDDDVDEDDDDEFGASVCEDNPEEAIARADHDTQQKQHYQPNASDSSYVENGRKLIQEP 202
            |:.:|:..:::.:|.|.:      |:..:|...:.|....:|:..:....|....|.     ::.
Zfish   146 DDKKEDKKEEIKKDGDKK------EEKKDEKEEKKDEKKDEKKDEKDEKKDEKKDEK-----KDE 199

  Fly   203 SKRSKPSALRRTLQALRQRLTKRNRPKPPD--WFLEKFSNTTNTDKIGKGCPAMEDAALSSEIRG 265
            .|..|....:...:..::...|::.|.||.  |.:
Zfish   200 KKDEKKDEKKDDKKDDKKDDKKKDAPPPPKEVWIM------------------------------ 234

  Fly   266 SSVLCNRLSVDPTLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLL 330
                      ||....:||||:|::..|.||::.:|.||.|.|:..:....|..|||..|.||.:
Zfish   235 ----------DPASDKYYRWLSIIAAPVFYNLMMLVTRACFNELQNTYTILWIVLDYTSDVIYYM 289

  Fly   331 DTLVHMHEGFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYI---WWPPETCSSLYLPC 392
            ||.|....|||:|||||:|:.:|..:|.....:..|::||:||||..:   :..||
Zfish   290 DTFVRSRTGFLEQGLLVKDSKKLINNYRTIPQFKYDMISMIPTDLFMLKVGFNNPE--------- 345

  Fly   393 PVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFSSDS 457
               :|.|||.::.||:|:||||||.|.|||.|||..:||.|||:||||||::||||..|||.:|:
Zfish   346 ---LRFNRLFKMARLFEFFDRTETRTNYPNIFRISNLVLYILVIIHWNACIFFAISKTIGFGTDT 407

  Fly   458 WVY-NLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDVEYLFVVADFLAGVLIFATIVGNI 521
            ||| |::......|.|:|||..||||||||||||||.|..|:||||||.|||.|||||||||||:
Zfish   408 WVYPNISHPEYGRLARKYIYCLYWSTLTLTTIGETPPPVRDIEYLFVVMDFLIGVLIFATIVGNV 472

  Fly   522 GSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKL 586
            |:||||||.:|.|||.::|.:||||.||:|..:||||||:||.|.|::....||:.||..|||||
Zfish   473 GAMISNMNASRAEFQAKIDSIKQYMQFRKVSKDLEARVIKWFDYLWTEKKTCDEKEVLKNLPDKL 537

  Fly   587 KAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSV 651
            ||||||.||:||||:||||.|.|.|||..|||||:.||||||||||:|||:|:||||:|.|||:|
Zfish   538 KAEIAINVHLDTLKKVRIFQDCEAGLLIELVLKLQPQVFSPGDYICKKGDIGREMYIIKEGKLAV 602

  Fly   652 VGDDGITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEA 716
            |.|||||....|..|:.|||:|:|.|.|::.|||||||:||:||||||.|:|.||.|.|::||:|
Zfish   603 VADDGITQFVVLSDGAYFGEISILGIKGSKAGNRRTANIRSVGYSDLFALSKDDLVEALTEYPDA 667

  Fly   717 RSTLTQRGCQLLRKDGLLDEQIFADSQRVHDSIEGGIEKLELSVENLNMRLARLLAEYTASQAKI 781
            :..|.::|..:||||.||||.:.|......| :|..|.:||.:::.:..:.|:|:||||:.|.||
Zfish   668 KKALEEKGKAILRKDNLLDEAVAAAGADPKD-LEEKIHRLEGNLDIMTGKFAKLMAEYTSYQGKI 731

  Fly   782 KQRLAKLE 789
            |||:..:|
Zfish   732 KQRITNME 739

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	119/223 (53%)
		Ion_trans_2	<477..527	CDD:285168	39/49 (80%)
		Crp	598..>722	CDD:223736	80/123 (65%)
		CAP_ED	604..717	CDD:237999	73/112 (65%)
		CLZ	720..791	CDD:293134	29/70 (41%)
cnga3a	XP_005166141.1	Ion_trans	272..483	CDD:278921	121/222 (55%)
		Crp	549..>671	CDD:223736	79/121 (65%)
		CAP_ED	555..671	CDD:237999	74/115 (64%)
		CLZ	671..741	CDD:293134	29/70 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170578283
Domainoid	1	1.000	289	1.000	Domainoid score	I1516
eggNOG	1	0.900	-	-		E1_KOG0500
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H994
Inparanoid	1	1.050	598	1.000	Inparanoid score	I925
OMA	1	1.010	-	-		QHG48384
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	1	1.000	-	-		FOG0000167
OrthoInspector	1	1.000	-	-		otm25512
orthoMCL	1	0.900	-	-		OOG6_100817
Panther	1	1.100	-	-	O	PTHR45638
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2458
SonicParanoid	1	1.000	-	-		X511
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	17	16.800