Protein Alignment CngA and cngb3.1

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_068075500.2
• Gene: cngb3.1 / 562675
• ZFINID: ZDB-GENE-090611-1
• Length: 987
• Species: Danio rerio
• Alignment Length: 579
• Identity: 167/579 - (28%)
• Similarity: 292/579 - (50%)
• Gaps: 67/579 - (11%)

  Fly   166 EEAIARADHDTQQKQHYQPNASDSSYVENGRKLIQEPSKRSKPSALRRTLQALRQRLTKRNRPKP 230
            ||.|.|.:.:.::|:       |.:.....:|..:|..|:.|...|:...:|..:...:...||.
Zfish   212 EERIKREEAEQKKKE-------DDAKRAAAKKEKEEKEKKEKEEKLKAEKEAADKEAAEAMFPKI 269

  Fly   231 P----DWFLEKFSNTTNTDKIGKGCPAMEDAALSSEIRGSSVLCNRLSVDPTLQSHY-RWLAIVS 290
            .    |..|:.|.     ||:        |:.|.:            ::||.....| :||::|:
Zfish   270 KCTCIDTLLKPFE-----DKM--------DSYLGA------------TIDPFTDRRYIKWLSVVT 309

  Fly   291 LAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLD-TLVHMHEGFLDQGLLVRDAFRLR 354
            :|..||:.....|..|.....:...||...|:|.|.:.::| |:......|:..|.:::|..:.:
Zfish   310 VAFNYNVWLATARLCFPYHTPATIPFWILFDFLADLVNVIDITMFQPRLQFVKAGDIIKDRVQTK 374

  Fly   355 RHYFHTKGWYLDVLSMLPTDLAYIWWPPETC-----SSLYLPCPVIVRLNRLLRINRLWEWFDRT 414
            ::|..:..:..|::|::|.||        .|     :|.:       ||||.:|....:|:.||.
Zfish   375 QNYRESARFQTDLISIIPFDL--------LCFQFGFTSFF-------RLNRFMRYQSFFEFSDRL 424

  Fly   415 ETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFSSDSWVYNLNGTRNNTLQRQYIYSFY 479
            |:.......:|:.:....:|..:|.|:|:|:..|...|..|..|.|       :.|...|:..:|
Zfish   425 ESIMAKAYIWRVGRTTGYLLYCLHINSCLYYVASEYEGLGSSRWTY-------DGLGNAYLRCYY 482

  Fly   480 WSTLTLTTIGETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQ 544
            ::|.||.|||..|.|....|.:|.:.:|..||.:|::::|.:..:|......:..|:..||....
Zfish   483 FATRTLITIGGLPEPHTLFEIVFQLVNFFTGVFVFSSLIGQMRDVIGAATAGQTYFRASMDSCVA 547

  Fly   545 YMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTE 609
            ||....:...:::||..|:.|||...|.|||..:|..:|..::..||:.:::.|.:::.:|...:
Zfish   548 YMNTYTIPKLVQSRVRTWYNYTWDSQGMLDESELLDKMPLVMRTAIAVDINLATFQKIDLFKGCD 612

  Fly   610 PGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVV-GDDGITVLATLGAGSVFGEVS 673
            ..:|..::|:||..|:.|||::|:|||:|:||||:|.|::.|: |.|...|..||.||.||||:|
Zfish   613 NQMLVDMLLRLKSIVYLPGDFVCKKGDIGREMYIIKAGEVQVIGGPDNKIVFVTLKAGCVFGEIS 677

  Fly   674 VLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRKDG 732
            :|:.|.: .||||||||.:.|:::||.|.|:||.:.|..|||::..|.::|.:|::..|
Zfish   678 LLQSAKD-GGNRRTANVAAHGFANLFVLDKKDLNDILIHYPESQKVLAKKGRKLMKAKG 735

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	66/253 (26%)
		CAP_ED	604..717	CDD:237999	54/113 (48%)
		CLZ	720..790	CDD:465160	4/13 (31%)
cngb3.1	XP_068075500.2	None