Protein Alignment CngA and cngb3.2

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_009295831.2
• Gene: cngb3.2 / 562466
• ZFINID: ZDB-GENE-091118-102
• Length: 801
• Species: Danio rerio
• Alignment Length: 726
• Identity: 197/726 - (27%)
• Similarity: 334/726 - (46%)
• Gaps: 97/726 - (13%)

  Fly    49 PASSAPAQLQLPCGSHQATLGVAPPPLEEISGGLFAPFAPTATITVEQAATSIPMAVDGEVHHLH 113
            |..:|||:...|....:.....||.|.:|..     |.||......|.||.: |.|..
Zfish    79 PEQAAPAKEPEPAAPAKEPEPAAPAPAKEPE-----PAAPAPAKEPEPAAPA-PAAKP------- 130

  Fly   114 YPRRSWQRKYRQGIHRQPGGGAEQDEDEEEDDDDVDEDDD----------------------DEF 156
                       :|....|......:|.:|.....:.|:.|                      |.:
Zfish   131 -----------EGTPADPANEQPPEEGKEPRPILISEEIDTHLIEMIQKLRQRTEQFKEKVIDPY 184

  Fly   157 GASVCEDNPEEAIARADHDTQQKQHYQPNASDSSYVENGRKLIQEPSKRSKPSALRRTLQALRQR 221
            .:|.....|...:.|.|      .:|:.........|..|...:|..||.:..|.::..:|.:::
Zfish   185 ASSPERSPPVTPVLRKD------DYYKLVEERKRQEEEERIRKEEEKKRKEEEAKKKKEEAEKKK 243

  Fly   222 LTKRNRPKPPDWFLEKFSNTTNTDKIGKGCPAMED-----AALSSEIRGSSV----------LCN 271
            ..:..:.|       |.......::.||.....:|     .::.|::..:.|          :.|
Zfish   244 KEEEEKKK-------KEEEEKKKEQAGKPVEKKDDKTDEKKSIFSKVNFTCVDFVLKPFEMRMDN 301

  Fly   272 RL--SVDPTLQSHY-RWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLDTL 333
            |:  |:||.....| .||::|::|..||:.||..|..|...:......|:|||.:.||||:.|.:
Zfish   302 RIGKSIDPFTDRRYITWLSMVTIAFNYNLWFVPVRMAFPYHSPEVVPLWFTLDIIADFIYIFDMI 366

  Fly   334 VHMHE-GFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWWPPETCSSLYLPCPVIVR 397
            ..... .|...|.::.|...:::.|..:..:..||:::||.||.||   |...:|::       |
Zfish   367 FFQPRLQFSKGGDIIYDREVIKKKYRESGRFQNDVIAVLPIDLLYI---PFGFNSVF-------R 421

  Fly   398 LNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFSSDSWVYNL 462
            ||||:::...:|:.||.|........:|:.:.:..:|.::|.|||:|:..|...|..|..|||:.
Zfish   422 LNRLMKVESFFEFSDRLEGLLTRAYIWRVIRTIGYLLFILHLNACLYYVASVSQGIGSTKWVYSG 486

  Fly   463 NGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISN 527
            .|:       .|:..|:::..:|..|.|.|.||.....:|.:.::..|.|..:.|:..:..:|..
Zfish   487 KGS-------AYLSCFFYAEKSLLMIAELPFPETMFGQIFQMTNYFVGALFLSIILAQMRDVIGA 544

  Fly   528 MNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAI 592
            ....:..|:..||....||....:...:::||..|:.|||...|.|||..:|..:|..::..||:
Zfish   545 ATAGQTYFRASMDACVAYMVTNHIPKMVQSRVRTWYNYTWDSQGMLDESELLGQMPLVMRTAIAV 609

  Fly   593 QVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVV-GDDG 656
            .:::.|.:::.:|...:..:|..::|:||..|:.|||::.:|||:||||||:|.|::.|: |.|.
Zfish   610 DINLATFQKIELFKGCDNQMLVDMLLRLKSIVYLPGDFVVKKGDIGKEMYIIKAGEVQVIGGPDN 674

  Fly   657 ITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLT 721
            ..|..||.||.||||:|:|:.:.| .||||||||.:.|:::||.|.|:||.:.|..|||::..|.
Zfish   675 KIVFVTLKAGCVFGEISLLQSSAN-GGNRRTANVAAHGFANLFVLDKKDLNDILIHYPESQKVLA 738

  Fly   722 QRGCQLLRKDG 732
            ::|.:||:..|
Zfish   739 RKGRKLLKAKG 749

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	70/248 (28%)
		CAP_ED	604..717	CDD:237999	54/113 (48%)
		CLZ	720..790	CDD:465160	5/13 (38%)
cngb3.2	XP_009295831.2	PLN03192	307..>704	CDD:215625	130/414 (31%)