Protein Alignment CngA and tax-4

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: NP_499033.1
• Gene: tax-4 / 176297
• WormBaseID: WBGene00006526
• Length: 733
• Species: Caenorhabditis elegans
• Alignment Length: 681
• Identity: 293/681 - (43%)
• Similarity: 412/681 - (60%)
• Gaps: 94/681 - (13%)

  Fly   184 PNASDSSYVENGRKLIQEP----SKRSKPSALRRTLQALRQRLT---KRNRPKPPDWFLEKFSNT 241
            |:.|..:...||   |..|    |..:|.|.|.:.|:...|..|   ::|.      |::|:...
 Worm    13 PSTSGLAPTTNG---IGSPPPTASAATKFSILTKFLRRKNQVHTTTAQQNE------FMQKYMPN 68

  Fly   242 TNTDKIGK----GCPAMEDAALSSE---------IRGSSVLCNRLSVDPTLQSHYRWLAIVSLAV 293
            .|::.:..    |.||..|...:.|         :|....|.| .:.||:..:.|.|..:|::|.
 Worm    69 GNSNAVQPAATGGQPASSDGGSAIEVPPPKESYAVRIRKYLAN-YTQDPSTDNFYYWTCVVTVAY 132

  Fly   294 LYNIIFVVGRAVFWEI-------------------------------NKSAPAF----------- 316
            :||::||:.|.||.::                               .|..|.:
 Worm   133 IYNLLFVIARQVFNDLIGPSSQSLCRFYNGTLNSTTQVECTYNMLTNMKEMPTYSQYPDLGWSKY 197

  Fly   317 ------WYTLDYLCDFIYLLDTLVHMHEGFLDQGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDL 375
                  |...|.|.|.:||:||.::...|::||||:||:|.::.:.|:.:|.:.:|.:|::|.|
 Worm   198 WHFRMLWVFFDLLMDCVYLIDTFLNYRMGYMDQGLVVREAEKVTKAYWQSKQYRIDGISLIPLD- 261

  Fly   376 AYI-WWPPETCSSLYLPCPVIVRLNRLLRINRLWEWFDRTETATGYPNAFRICKVVLAILVLIHW 439
             || .||....:...||   |:|||||:|..|:....:||||.:..|||||:..||..|:::|||
 Worm   262 -YILGWPIPYINWRGLP---ILRLNRLIRYKRVRNCLERTETRSSMPNAFRVVVVVWYIVIIIHW 322

  Fly   440 NACMYFAISYEIGFSSDSWVY------NLNGTRNNTLQRQYIYSFYWSTLTLTTIGETPTPENDV 498
            |||:||.||..||..:|:|||      :|.....:||.|:|:||||||||.||||||.|:|..::
 Worm   323 NACLYFWISEWIGLGTDAWVYGHLNKQSLPDDITDTLLRRYVYSFYWSTLILTTIGEVPSPVRNI 387

  Fly   499 EYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWF 563
            ||.||..|.:.|||||||||||:|||||||:.||.||||:|||:||||..|:|..:||.|||:||
 Worm   388 EYAFVTLDLMCGVLIFATIVGNVGSMISNMSAARTEFQNKMDGIKQYMELRKVSKQLEIRVIKWF 452

  Fly   564 AYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPG 628
            .|.|:...:|.:::||..|||||:||||:|||.:||::||||.|.|.|||..|||||:|||||||
 Worm   453 DYLWTNKQSLSDQQVLKVLPDKLQAEIAMQVHFETLRKVRIFQDCEAGLLAELVLKLQLQVFSPG 517

  Fly   629 DYICRKGDVGKEMYIVKRGKLSVVGDDGITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSL 693
            |:||:|||:|:||||||||:|.||.|||..|..||..||||||:|:|.|||::.||||||||||:
 Worm   518 DFICKKGDIGREMYIVKRGRLQVVDDDGKKVFVTLQEGSVFGELSILNIAGSKNGNRRTANVRSV 582

  Fly   694 GYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRKDGLLDEQIFADSQRVHDSIEGGIEKLEL 758
            ||:|||.|:|.|||..|.:||:||..|..:|.::|:||.||||    ::.....::|...|.|..
 Worm   583 GYTDLFVLSKTDLWNALREYPDARKLLLAKGREILKKDNLLDE----NAPEEQKTVEEIAEHLNN 643

  Fly   759 SVENLNMRLARLLAEYTASQAKIKQRLAKLE 789
            :|:.|..|:|||:.|:::::.|:.:|:..||
 Worm   644 AVKVLQTRMARLIVEHSSTEGKLMKRIEMLE 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	120/301 (40%)
		CAP_ED	604..717	CDD:237999	77/112 (69%)
		CLZ	720..790	CDD:465160	23/70 (33%)
tax-4	NP_499033.1	PLN03192	208..>564	CDD:215625	200/360 (56%)
		CAP_ED	493..610	CDD:237999	79/116 (68%)
		CLZ	609..675	CDD:465160	23/70 (33%)