Protein Alignment CngA and LOC1275026

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_061508473.1
• Gene: LOC1275026 / 1275026
• VectorBaseID: AGAMI1_012358
• Length: 2010
• Species: Anopheles gambiae
• Alignment Length: 748
• Identity: 233/748 - (31%)
• Similarity: 366/748 - (48%)
• Gaps: 126/748 - (16%)

  Fly   168 AIARADHDTQQKQHYQPNASDSSYVENGRKLIQEPSKRSKPS----ALRRTLQALRQRLTKRNRP 228
            |.:|.:.|....|     ||..|         :...:|:|.:    .||.|:|     ::...:.
Mosquito   162 ATSRDEEDDSSNQ-----ASSGS---------KGSGQRTKSNQRWMKLRTTVQ-----ISSAMQK 207

  Fly   229 KPP----DWFLEKFSNTTNTDKIGK--------GCPAMEDAALSSEIRGSSVLCNRLSVDPTLQS 281
            |||    |.||::||    |.:|.:        |.....||..:...|.......|..|:|....
Mosquito   208 KPPLKREDSFLKRFS----TRQIPEAQETVEDTGSEGATDAEKTVRRRRRFAKIPRTVVNPDENF 268

  Fly   282 HYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLDTLVHMHEGFLDQGLL 346
            ::.||.:|::::|||:..::.|..|.|:..:|..||.:.|...|.:::.|..|.:..|:|:|||:
Mosquito   269 YFYWLMLVTISILYNLWTLIVRQSFPELQSNASRFWLSCDCFTDIVFIFDVAVQLRTGYLEQGLM 333

  Fly   347 VRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWWPPETCSSLYLPCPVIVRLNRLLRINRLWEWF 411
            |.|:.:|..||..::.:.||:.:::|.|:.          ...|....::|..|..::.|..:::
Mosquito   334 VYDSRKLAGHYLRSRAFLLDLAALVPLDIL----------QFRLGSQPMLRFPRFFKVYRAVKYY 388

  Fly   412 DRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFSSDSWVYNLNGTRNNTLQRQYIY 476
            ...|:.|.:||.:|:..::..:|:|.||..|.||.:|...||..| |||........||.|:|:.
Mosquito   389 YIVESRTVWPNLWRVVNLIHILLILAHWFGCFYFLLSEAEGFQGD-WVYPYRPGDYATLTRKYLG 452

  Fly   477 SFYWSTLTLTTIGETPTPENDVE----------------------------YLFVVADFLAGVLI 513
            |.|||||||||||:.||||.:.|                            |:|.:..:|.||.|
Mosquito   453 SLYWSTLTLTTIGDLPTPETNAEPSQSADGPRSLPRRGLKSRLLQFNSSRGYVFTIVSYLIGVFI 517

  Fly   514 FATIVGNIGSMISNMNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQ---SGALDE 575
            ||||||.:|::|:|.|..|:||:..:||.|.||...:|...::.||:||:.|:||:   .|..|.
Mosquito   518 FATIVGQVGNVITNRNANRLEFERLLDGAKTYMRHHKVPGGMKRRVLRWYDYSWSRGRIQGGGDI 582

  Fly   576 ERVLAALPDKLKAEIAIQVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKE 640
            ...|..||||||.|:|:.|::..||:|.||.:.:|..|..||||:|..:|:|||.|||||:|.:|
Mosquito   583 NTALGLLPDKLKTELALHVNLSVLKKVTIFQECQPEFLHDLVLKMKAYIFTPGDSICRKGEVARE 647

  Fly   641 MYIVKRGKLSVVGDDGITVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRD 705
            |:|:..|.|.|:.:.| .||.|:.||..|||:.:|.:.|.   |:|||:|||:|||:||.|::.|
Mosquito   648 MFIIADGILEVLSETG-KVLTTMKAGDFFGEIGILNLDGL---NKRTADVRSVGYSELFSLSRED 708

  Fly   706 LWETLSDYPEARSTLTQRGCQLLRKDGLLD---------------EQIFADSQRVH----DSIEG 751
            :...:.|||||:..|     |.|.:..|::               |.....|...|    ||.:.
Mosquito   709 VLTAMKDYPEAQEIL-----QTLGRKRLMEVRCVNKKHANKHAAKEHAGDRSSNTHNNQGDSSDN 768

  Fly   752 G-----IEKLELSVENLN--MRLARLLAEYTASQAKIKQRLAKLEMNG----GPGTWRLECEPQS 805
            .     ::||...|:.|.  :|.:|     |.:..:..:.:....::|    |.|:........:
Mosquito   769 SASKRIVDKLRSDVKGLKNVLRKSR-----TGTTRRSNESIEMQPLHGNATSGGGSGGAGSGGSA 828

  Fly   806 RARSGRLYSLQPKRRPRSRPDATAKSSDAAKQN 838
            .:...:......||.||.:.| ...:.|..|.|
Mosquito   829 GSGGSKTSKTMLKRMPRVKSD-DIHTEDEGKDN 860

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	89/274 (32%)
		CAP_ED	604..717	CDD:237999	54/112 (48%)
		CLZ	720..790	CDD:465160	16/95 (17%)
LOC1275026	XP_061508473.1	None