Protein Alignment CngA and sei

DIOPT Version :10

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_061505894.1
• Gene: sei / 1269513
• VectorBaseID: AGAMI1_008290
• Length: 1670
• Species: Anopheles gambiae
• Alignment Length: 927
• Identity: 205/927 - (22%)
• Similarity: 366/927 - (39%)
• Gaps: 219/927 - (23%)

  Fly    16 TMMSNRRRPETESPKYGYNLSNRPMYRTT---RLVGPASSAPAQLQLPCGSHQATLGVAPPPLE- 76
            |::||.|       |..:.:..:|..|.|   ....|..:.|..||||.|        .|..:|
Mosquito   594 TILSNLR-------KAAHAVHVKPANRETCGCSTSSPIPNPPNTLQLPIG--------VPATVEQ 643

  Fly    77 --EISG-------GLFAPFAPTATITVEQAATSIPMAVDGEVHHLHYPRRSWQRKYRQGIHRQPG 132
              |.||       ...||......:.:.:....:|:::. .::.....|..:..|
Mosquito   644 SCEDSGKSVHRKNQCLAPDEDNRIVNIIETPNIVPISMK-SLNSALSERLCYTTK---------- 697

  Fly   133 GGAEQDEDEEEDDDDVDEDDDDEFGASVCEDNPEEAIARADHDTQQKQHYQPNASDSSYVENGR- 196
              |::..|.:.|...:.:.:      ||...:....::|       |..::.|:.|:...|..:
Mosquito   698 --AQKSFDNKSDKSLLSQAN------SVKSRSKFSPLSR-------KVSHKTNSFDTEPTEGAKE 747

  Fly   197 --------KLIQEP--SKRSKPSALRRTLQALRQRLTKRNRPKPPDWFLEKFSNTTNTDKIGKGC 251
                    |::.||  :.:.|.|::|.:..:.:.::...|.       :...||.......|
Mosquito   748 SLLGHKFEKILPEPVETAQEKWSSVRLSSDSKKNQIKIENH-------ISTHSNLNLNGLSG--- 802

  Fly   252 PAMEDAALSSEI--RGSSVLCNRLSVDPTLQS----HYR-----WLAIVSLAVLYNIIFVVGRAV 305
               :.|.|..|:  .|:.||.......|.:..    ||.     |..|:.|.|:|..||....|.
Mosquito   803 ---DKANLGKEVLSLGADVLPEYKLQSPRVHKWTILHYSPFKAVWDWIILLLVMYTAIFTPYVAA 864

  Fly   306 FW---------EINKSAPAFWYTLDYLCDFIYLLDTLVHMHEGFLD-QGLLVRDAFRLRRHYFHT 360
            |.         :..|.|......:|.:.|..:::|.|::....|:: |..:|....|:..||.
Mosquito   865 FLLSEPDYNQRKNRKYADDPIVIIDLIVDVTFVVDILINFRTTFVNGQDEVVSHPGRIAVHYL-- 927

  Fly   361 KGWYL-DVLSMLPTDLAYIWW--------PPETCSSLYLPCPVIVRLNRLLRINRLWEWFDRTET 416
            .||:| |:::.:|.||..:..        ..||.:.:.|     ::..||||:.|:....||
Mosquito   928 SGWFLIDLVAAIPFDLLLVGSDTDELGLDKDETTTLIGL-----LKTARLLRLVRVARKIDR--- 984

  Fly   417 ATGYPNAFRICKVVLAILVLI-HWNACMYFAI--------SYEIGF----SSDSWVYNLNGTRNN 468
            .:.|..|  :..:::|...|| ||.||:::||        ..:||:    :.|:..|..   .||
Mosquito   985 YSEYGAA--VLVLLMATFALIAHWLACIWYAIGNAERPLLKAKIGWLDALAQDTQEYYF---PNN 1044

  Fly   469 T-----LQRQYIYSFYWSTLTLTTIG-ETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISN 527
            |     ::.:|:.:.|::..:||::| ....|..|.|.:|.:...|.|.|::|:|.||:.::|..
Mosquito  1045 TGGGPSVKSRYVTALYFTFTSLTSVGFGNVAPNTDAEKIFTICVMLVGSLMYASIFGNVSAIIQR 1109

  Fly   528 MNVARVEFQNRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAI 592
            :......:..:|..|::::.|.::.:.|..|:..:|.:.|:.:..:|...||...|:.|:|:|.:
Mosquito  1110 LYSGTARYHTQMLRVREFIRFHQIPNPLRQRLEEYFQHAWTYTNGIDMNSVLKGFPECLQADICL 1174

  Fly   593 QVHMDTLKQVRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDGI 657
            .::.:.|.....|....||.|.||.||.|.....|||.:..||||...:|.:.||.:.::.||
Mosquito  1175 HLNRNLLNNCSAFEAASPGCLRALSLKFKTTHAPPGDILVHKGDVLTYLYFIARGSIEILKDD-- 1237

  Fly   658 TVLATLGAGSVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLTQ 722
            .|:|.||...:|||...:    :.|..:..:||::|.|.||..:.:.||.:.|..:||
Mosquito  1238 VVMAILGKDDIFGENPCI----HSTLGKSNSNVKALTYCDLHKIHRDDLLDVLDLFPE------- 1291

  Fly   723 RGCQLLRKDGLLDEQIFADS--------QRVHDSIEGGIEKLELSVENLNMRLARLLAEYTASQA 779
                            |.||        ..:.|..:.|:|        |..|..|..::...|:.
Mosquito  1292 ----------------FYDSFVNSLEITYNMRDEEQAGVE--------LRHRYMRTGSQDRESET 1332

  Fly   780 KIKQRLAKLEMNGGPGTWRLECE-PQSRARSGRL----------------------------YSL 815
            :...|......:..||.   :|: |..|:..|::                            |..
Mosquito  1333 RSYVRKLNTVHHRPPGN---KCDMPNDRSSIGQMSTNYDDDRKFSLSGIINQLKRSIPDLNSYKH 1394

  Fly   816 QPKRRPRSRPDATAKSS 832
            ||.....:.|:.:.||:
Mosquito  1395 QPLTNKCASPNESPKST 1411

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	282..529	CDD:459842	75/289 (26%)
		CAP_ED	604..717	CDD:237999	40/112 (36%)
		CLZ	720..790	CDD:465160	11/77 (14%)
sei	XP_061505894.1	None