Protein Alignment CngA and cnga4

DIOPT Version :9

• Sequence 1: NP_001188960.1
• Gene: CngA / 36806
• FlyBaseID: FBgn0261612
• Length: 840
• Species: Drosophila melanogaster
• Sequence 2: XP_017945387.2
• Gene: cnga4 / 100489546
• XenbaseID: XB-GENE-996762
• Length: 573
• Species: Xenopus tropicalis
• Alignment Length: 604
• Identity: 256/604 - (42%)
• Similarity: 369/604 - (61%)
• Gaps: 38/604 - (6%)

  Fly   215 LQALRQRLTKRNRPKPPDWFLEKFSNTTNTDK--IGKGCPAMEDAALSSEIRGSSVLCNRLSVDP 277
            :..|.|.::.|         :|:.......:|  |......||:....|....||:|      ||
 Frog     1 MNTLTQMMSHR---------MERIKEEAKMEKEEIKAWTQPMENTVNPSTRNRSSIL------DP 50

  Fly   278 TLQSHYRWLAIVSLAVLYNIIFVVGRAVFWEINKSAPAFWYTLDYLCDFIYLLDTLVHMHEGFLD 342
            ....:|.||.|:.|.|.||.:.::.|:.|.|:.......|.:||||||.:|::|.:.:.|.|||:
 Frog    51 AGNWYYCWLNIMVLPVTYNWVIIICRSCFPELQYQYLPVWLSLDYLCDVLYVMDIIANFHTGFLE 115

  Fly   343 QGLLVRDAFRLRRHYFHTKGWYLDVLSMLPTDLAYIWWPPETCSSLYLPCPVIVRLNRLLRINRL 407
            :|:||.|...:.|||..:..:..|::|:||||..|.        .|.:..|. ||:||.||.:||
 Frog   116 EGILVTDRHLIARHYISSSKFRWDLISVLPTDFLYF--------KLGIHTPA-VRINRFLRFHRL 171

  Fly   408 WEWFDRTETATGYPNAFRICKVVLAILVLIHWNACMYFAISYEIGFSSDSWVY-NLNGTRNNTLQ 471
            :|.||||||...|||||||||::..|.|:||||:|:|||:|..|||..|.||: |:..:....|.
 Frog   172 FESFDRTETRIPYPNAFRICKLMAYIFVVIHWNSCVYFALSSFIGFGKDKWVHPNITDSDFARLG 236

  Fly   472 RQYIYSFYWSTLTLTTIGETPTPENDVEYLFVVADFLAGVLIFATIVGNIGSMISNMNVARVEFQ 536
            |||:||||:|||.|||:|:.|.|..:.|:||:|.|||..||.||||:|::.|::||||.|...|.
 Frog   237 RQYLYSFYFSTLILTTVGDIPPPVQEEEWLFMVVDFLIAVLGFATIMGSMTSVVSNMNSADEAFY 301

  Fly   537 NRMDGVKQYMAFRRVGHELEARVIRWFAYTWSQSGALDEERVLAALPDKLKAEIAIQVHMDTLKQ 601
            ...|.||.|:...:|...::.:||.|..:........:|..:|..||:||:.|:|:.||:..|.:
 Frog   302 PNYDNVKLYLKMYKVNRSVKKKVIAWHQHLQIYKKLTNENDILQNLPEKLRVEVAVSVHLPILSK 366

  Fly   602 VRIFHDTEPGLLEALVLKLKLQVFSPGDYICRKGDVGKEMYIVKRGKLSVVGDDGITVLATLGAG 666
            |:||.:.|..|||.||||||.||:|||:|:|:|||:|:||||:|.|||:||.|||:|..|.||.|
 Frog   367 VQIFQNCEKSLLEELVLKLKPQVYSPGEYVCKKGDIGREMYIIKEGKLAVVADDGVTQFAELGEG 431

  Fly   667 SVFGEVSVLEIAGNRTGNRRTANVRSLGYSDLFCLAKRDLWETLSDYPEARSTLTQRGCQLLRKD 731
            :.|||:|:|.|.||.:|||||||::|:||||||||:|.||.:.|.:||:|::.|.|:|.::|.|.
 Frog   432 NYFGEISILNIRGNTSGNRRTANIKSIGYSDLFCLSKEDLRDALREYPDAKAILEQKGREILLKM 496

  Fly   732 GLLDEQIFADSQRVHDSIEGGIEKLELSVENLNMRLARLLAEYTASQAKIKQRLAKLEMNGGPGT 796
            ..||||:..:.......:|..:.:||.::::|..:|||||||..:|..|:.||:.:||
 Frog   497 NKLDEQLADELAAKEQELEMKVGRLESNLDSLQTKLARLLAELESSAVKMTQRIRQLE------- 554

  Fly   797 WRL----ECEPQSRARSGR 811
            |.:    |..|.:....|:
 Frog   555 WEISLWEEKVPGATGADGK 573

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CngA	NP_001188960.1	Ion_trans	309..529	CDD:278921	105/220 (48%)
		Ion_trans_2	<477..527	CDD:285168	27/49 (55%)
		Crp	598..>722	CDD:223736	75/123 (61%)
		CAP_ED	604..717	CDD:237999	71/112 (63%)
		CLZ	720..791	CDD:293134	26/70 (37%)
cnga4	XP_017945387.2	Ion_trans	55..295	CDD:395416	117/248 (47%)
		CAP_ED	369..485	CDD:237999	72/115 (63%)
		CLZ	485..555	CDD:406832	26/76 (34%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I1626
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1073751at2759
OrthoFinder	1	1.000	-	-		FOG0000167
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR45638
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	7.020