Protein Alignment krimp and Tdrd7

DIOPT Version :10

• Sequence 1: NP_611103.2
• Gene: krimp / 36804
• FlyBaseID: FBgn0034098
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: XP_006238169.1
• Gene: Tdrd7 / 85425
• RGDID: 619724
• Length: 1146
• Species: Rattus norvegicus
• Alignment Length: 814
• Identity: 156/814 - (19%)
• Similarity: 275/814 - (33%)
• Gaps: 286/814 - (35%)

  Fly    26 SYQTEM-HQIHKELTEKLSHADL---LYRSLIPLHDHLVASLSEVNAHVMKLNVQLHINRQSVRL 86
            |:.|:. |...|  |.|:..|||   :.|:::..|.:.:. |..:......|.
  Rat    19 SWHTDQGHSASK--TAKMLEADLVSKMLRAVLQSHKNGIV-LPRLQGEYRSLT------------ 68

  Fly    87 GDYEYYEKSIDNPYSSIRSGLQAIEKPGCAEAICQSSKPAFVECLPSSTSEEVP--VVAVQEASS 149
            ||:..:::.   .|.::.:.|:::              ||.|. :.:|.|.|:.  .||..|.:.
  Rat    69 GDWIPFKQL---GYPTLEAYLRSV--------------PAVVR-IEASRSGEIVCYAVACTETAR 115

  Fly   150 TNQLDAISVVNENLSEERDATPQPLAVSKNMEETMPSNPFHEQLEGSLEEIPVGSKIVVETEKAN 214
            ..||    |..:..|:.:  |.:.:.....:::||   ||.  |||                |..
  Rat   116 IAQL----VARQRTSKRK--TGRQINCQMRVKKTM---PFF--LEG----------------KPK 153

  Fly   215 NPVRSEASAP----ATSDNQSLLAAKQGTQTIGTGICNKISKSTINMP--------NNWQLENPT 267
            ..:|....|.    :...|.:||..|  ..|:|       :|:.::||        .:..:...:
  Rat   154 ATLRQPGFASDYSISKKPNPTLLREK--GSTLG-------AKADVDMPPYPDAPVQRHVSMSANS 209

  Fly   268 EVT-------AASIEKVNKLPKSPRNRFLLPPKGG------TETTRRDIYNQILKDMAAFPE--N 317
            .||       |:.::.:...|| |....|..||..      |..:|            |.|:  |
  Rat   210 SVTVLRSHPEASKLQFMGYSPK-PHCLLLFSPKSSLPAPFQTHISR------------ACPKEVN 261

  Fly   318 TIVTAVLASVDVTDNCAYVAKWDESSDRIKKVLQRQLPLQELDQLPDYGDIFAVLDSINNIITR- 381
            ..:...:...:||...:|..|.||..:|||::|.:......:.:||.:...|...|....::.:
  Rat   262 DNLNQTVEKPNVTPPASYTNKMDEVQNRIKEILDKHNNGIWISKLPHFYKEFYKEDLNQGVLQQF 326

  Fly   382 -----ITINSSSAGGGYDAYLIDFGEHIHFDGNETIFKLPDDIKRLPA---QAIRCDLINCDIAN 438
                 |.......|||.|..|                        .||   |.:|.|
  Rat   327 EHWPHICTVEKPCGGGQDLLL------------------------YPAKREQPLRSD-------- 359

  Fly   439 MHCFVNTYIKIRVHENNNSTLVAEPVIDRLSRPTKTNTT--------------KYPAGI------ 483
                          ::........|...|...|:|.:..              ||.:|:
  Rat   360 --------------QDPEKERPPPPPAPRQEVPSKGSPAVMPDVKEKVAELLGKYSSGLWASALP 410

  Fly   484 -----------TED---------DMAMLNEIDESTSDPLKAVLGFR---P-----KDEQRICRHY 520
                       .||         |:..:|.|..:|.   ||:|..:   |     |||.:....:
  Rat   411 KAFEDMYKVKFPEDALKNLASLSDVCTINYISGNTQ---KAILYAKLPLPTDKILKDEAQAQGDF 472

  Fly   521 DPKLNGCFKGNNCRFAHEPFAPNGATKDVELARALPETIFDTTVHFEIGSIV-------GILITF 578
            |.|          ....:.:        :::.:.:.|:..|......:..:|       .:|:..
  Rat   473 DIK----------SMIEQEY--------LQIEKNMAESADDFVEDITVPPLVIPTEASPSVLVVE 519

  Fly   579 INGPTEV----YGQFLDGSPPLVWDKKDVPENKRTFKSKPRLLDI-------VLALYS-DGCFYR 631
            ::...:|    .|:....:..|:.|     |.|..:...||:..|       :||:.: :..:.|
  Rat   520 LSNTNDVVIRYVGKDYSAAQELMED-----EMKEYYSRNPRVTPIQTVHVGQLLAVNAEEDAWLR 579

  Fly   632 AQIIDEFPSEYMIFYVDYGNTEFVPLSCLAPCENVDSFKPHRVFSFHIEGIVRSKNLTHQKTIEC 696
            ||||....::..:.|||||.           |||::..|.:|:..       |..:|:.|.| :|
  Rat   580 AQIISTDENKIKVCYVDYGF-----------CENIEKSKAYRLNP-------RFCSLSFQAT-KC 625

  Fly   697 IEYLKSKLLNTEMN-VHLVQRLPDG--FLIRFLD 727
             :....::||.:.| |.:|:.|..|  |.:..||
  Rat   626 -KLAGLEILNDDPNLVKVVESLTCGKIFAVEILD 658

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
krimp	NP_611103.2	TUDOR	576..679	CDD:425754	26/114 (23%)
		Tudor_dTUD-like	618..663	CDD:410450	13/52 (25%)
Tdrd7	XP_006238169.1	LOTUS_1_TDRD7	38..124	CDD:193600	22/120 (18%)
		LOTUS_2_TDRD7	283..349	CDD:193587	16/89 (18%)
		LOTUS_3_TDRD7	388..452	CDD:193588	12/66 (18%)
		Tudor_SF	540..637	CDD:470623	31/121 (26%)
		Tudor_TDRD7_rpt2	701..840	CDD:410499
		Tudor_TDRD7_rpt3	978..1068	CDD:410500