Protein Alignment krimp and Tdrd5

DIOPT Version :10

• Sequence 1: NP_611103.2
• Gene: krimp / 36804
• FlyBaseID: FBgn0034098
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: NP_001128213.1
• Gene: Tdrd5 / 214575
• MGIID: 2684949
• Length: 1040
• Species: Mus musculus
• Alignment Length: 723
• Identity: 127/723 - (17%)
• Similarity: 238/723 - (32%)
• Gaps: 285/723 - (39%)

  Fly   151 NQLDAISVVNENLSEERDATPQPLAVSKNMEETMP---------SNPFHEQLEGSLEE-IPVGSK 205
            :..:.::..::.:|.|:......|.:.|::.|...         :.||..:.:||... .||
Mouse   169 SMFEVLNAASDVISVEQTRAGSLLTLKKSVSEDKQRGWPAGKVFTQPFRMKQQGSYSTGFPV--- 230

  Fly   206 IVVETEKANNPVRSEASAPATS---DNQSLLAAKQGTQTIGTGICNKISKSTINMPNNWQLENPT 267
                       :::..|.|.::   ..|.|..||       |...|.:..|.:|
Mouse   231 -----------MKAHFSQPISNMEPPKQVLSMAK-------TPTFNSVEASRLN----------- 266

  Fly   268 EVTAASIEKVNKLPKSPRNRFLLPPKGGTETTRRDIYNQILKDMAAFPENTIVTAVLASVDVTDN 332
                 ..||:|:|..:.::.......||  |...::..:|...::.||:...::.:|...::|
Mouse   267 -----HTEKLNQLESTFKSVIAQIGPGG--TVDPELKRKIQFVVSKFPQGLFISKLLGEFELT-- 322

  Fly   333 CAYVAKWDESSDRIKKVLQRQLPLQELDQLPDYGDIFAVLDSINNIITRITINSSSAGGGYDAYL 397
                             .:.||..::|..|    ::..::.::::|:.
Mouse   323 -----------------FKEQLSPKQLGFL----NVTELVGALSDILR----------------- 349

  Fly   398 IDFGEHIHFDGNETIFKLPDDIKRLPA----QAIRCDLINCDIANMHCFVNTYIKIRVHENNNST 458
            ::|.|.     .:.:.....|:|.||:    .::|                           ||.
Mouse   350 VEFSEE-----RQDLLVFDADLKPLPSGGPLSSVR---------------------------NSC 382

  Fly   459 LVAEPVIDRLSRPTKTNTTKYPAGITEDDMAMLNEIDESTSD-PLKAVLGFRPKDEQRICRHYD- 521
            || :|  |:     ||....:.:.::.:.::.: .:.::|.| |||.    :.:.||:|.:..:
Mouse   383 LV-QP--DK-----KTEANPWTSSLSRNSLSTV-AVKKTTWDCPLKN----QKEPEQKIYKKPNL 434

  Fly   522 -------------PKLNGCFKGNNCRFAHEPFAPNGATKDVELARALPETIFDTTVHFEIGSIVG 573
                         |:|       :...|:....|: |.:..:|.|..|   .||:      ::||
Mouse   435 VVKPLQLQVETNKPQL-------SLSVANHDIPPD-AVRAKKLCRLPP---LDTS------TLVG 482

  Fly   574 ILITFINGPTEVY--------GQFLDG---------SPPLVWDKKDVPENKRTFKSKPRLLDIVL 621
            :.:.:|..|::.|        .:.|:.         |..||.|:..:||    :..:|..|..|
Mouse   483 VFVEYIISPSQFYIRIYSRDSSELLEDMMIEMRRCYSNQLVSDRYIMPE----YFIQPGHLCCV- 542

  Fly   622 ALYSDGCFYRAQIIDEF--PSEYMIFYVDYGNTEFVPLSCL--------------APC------- 663
            .:..|..:||. ||...  ..|..:||.|:||...|..|.|              .||
Mouse   543 KISEDKWWYRV-IIHRILGKKEVEVFYPDFGNIGTVQKSSLRFLKCCYTKLPAQAIPCSLAWVRP 606

  Fly   664 -------------ENVDSFKP-HRVFSFHIEGIVR------SKN---------LTHQKTIECIEY 699
                         :.:...|| ..|...:|:||:.      |.|         .|....|.|.|.
Mouse   607 AEEHWTARAILHFQKLCGLKPLVGVVDEYIDGILNIFLCDTSSNEDVYFHHVLRTEGHAIVCREN 671

  Fly   700 LKSK--------------------------------LLNTEMNV--HLVQRLPDGFLIRFLDDWK 730
            ..||                                .||.:..:  ...|.:.||..|.:|   |
Mouse   672 APSKGFRDFNPPALYTNASSAGDMVLTDLGHPAQQHYLNEDQEILQQAQQDINDGKCISYL---K 733

  Fly   731 YIPEQLLQ 738
            ..|::||:
Mouse   734 SAPKELLK 741

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
krimp	NP_611103.2	TUDOR	576..679	CDD:425754	32/156 (21%)
		Tudor_dTUD-like	618..663	CDD:410450	15/60 (25%)
Tdrd5	NP_001128213.1	LOTUS_1_TDRD5	4..98	CDD:193599
		LOTUS_2_TDRD5	127..196	CDD:193589	3/26 (12%)
		LOTUS_3_TDRD5	292..365	CDD:193590	12/117 (10%)
		Tudor_TDRD5	484..601	CDD:410490	29/122 (24%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	857..891
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	912..975