DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment krimp and si:ch211-189e2.3

DIOPT Version :9

Sequence 1:	NP_611103.2	Gene:	krimp / 36804	FlyBaseID:	FBgn0034098	Length:	746	Species:	Drosophila melanogaster
Sequence 2:	XP_021328732.1	Gene:	si:ch211-189e2.3 / 100536102	ZFINID:	ZDB-GENE-030131-6454	Length:	1813	Species:	Danio rerio

Alignment Length:	722	Identity:	141/722 - (19%)
Similarity:	265/722 - (36%)	Gaps:	156/722 - (21%)

- Green bases have known domain annotations that are detailed below.

  Fly    26 SYQTEMHQIHKELTEKLSHADLLYRSLIPLHDHL------VASLSEVNAHVMKLNVQL-----HI 79
            |.||::...:.: .|..|::|.|::.|.|   .|      :.::::| .|.:|:..:|     .:
Zfish   210 SIQTDLLTTNGQ-QEHASNSDRLWQYLYP---ELSPGTIEIVTVTQV-VHPLKIYCKLCVFSQEL 269

  Fly    80 NRQSVRLGDYEYYEKSIDNPYSSIRSGLQAIEKPGCAEAIC--QSSKPAFVECL--PSSTSEEVP 140
            .:.||:|  ||:||.:..          ..|..|.|..:.|  :.|...:...:  .:..|:.|.
Zfish   270 KKLSVQL--YEHYEDAFS----------AQIPVPLCDGSPCATKGSDGKWYRSVLQQNDISDVVK 322

  Fly   141 VVAVQ-------EASSTNQLDA----ISVVNENLSEERDATPQPLAVSKNMEETMPSNPFHEQLE 194
            |..|.       :.|:...|.|    :.||....| ......:.:....:..:.:.|....:.|.
Zfish   323 VFHVDYGIGDFVKLSNIRPLSARFFHLPVVTYGCS-LHGVIDKGVGWRTDQIDYLKSVILDQILV 386

  Fly   195 GSLEEIPVGSKIVVETEKANNPVRSEASAPATSDNQSLLAAKQ---GTQTIGTGICNKISKSTIN 256
            |..|...|...:...|...|:.|....:   ....:..||..:   |..|:.|  .||::...::
Zfish   387 GKFEHYSVSEGVYYITLYGNDNVNVNLT---FGHKEHCLAVNEKMCGDPTLDT--LNKVTYGNMH 446

  Fly   257 MPNN-WQLENPTEVT--AASIEKVNKLPKSPRNRFLLPPKGG-------TETTRRDIYNQILKDM 311
            ..|| .|..:...:|  ::|:|.||.:..|.....|...|||       |.:.:.|.|..:...:
Zfish   447 GRNNSLQSLHSAHLTEYSSSVEDVNVVGPSKAEGNLQSTKGGYTLNAATTSSLQADAYVDVPPKI 511

  Fly   312 AAFPENTIVTAVLASVDVTDNCAYVAKWDESSDRIKKV------LQRQLPLQELDQLPDYGDIFA 370
            ....:..:....:.||:     .:...:.:::|.:.|:      |.|:.|..:....|....:..
Zfish   512 KVGAKMKLHITCVESVN-----QFYGHFAQNTDAVAKMTKDIQQLCRKRPQAKFSISPKMMCLAK 571

  Fly   371 VLD------SINNIITRITINSSSAGGGYDAYLIDFGEHIHFDGNETIFKLPDD---IKRLPAQA 426
            ..|      .|.::..:|.:.           .:|:|:.:..|.:: |...|.:   |..||.||
Zfish   572 FSDGQWHRGQIESVHPKILVQ-----------FVDYGDLVVVDKSD-ILPFPPNANAIASLPIQA 624

  Fly   427 IRCDLIN------CDIAN------MHCFVNTYIKIRVHENNNSTLVAEPVIDR---------LSR 470
            ::.:|.|      |::..      ..|..|..:|:    |::..|..|...|:         |..
Zfish   625 VQFELFNVALPEPCELNEWFKNYATDCMFNVVVKL----NSSGKLSVEMYDDKTNLNLKIKDLWS 685

  Fly   471 PTKTNTTKYPAGI--------TEDDMAMLNEIDES---TSDPLKAVLGFRPKDEQRICRHYDPKL 524
            .||.|.:....||        |.:.|. ..|:..|   ||...:..|  :|..:.|..:::....
Zfish   686 KTKRNESINTKGIVKTRGFKETSEGME-FREVRNSFSTTSQAHERTL--KPVGQARTEQNFQSAT 747

  Fly   525 N-GCFKGNNCRFAHEPFAPNGATKDVELARALPETIFDTTVHFEIGSIVGILITFINGPTEVYGQ 588
            . ....|||..:      ||...:.|.....|.|....|   .::|.:..:.::..|.|:..:.|
Zfish   748 GYSNATGNNRAW------PNVLQQQVMAYPKLTELPLRT---IDVGYVSDVYVSHCNSPSNFFVQ 803

  Fly   589 FLDGSPPL--VWDK------KDVPENKRTFKSKPRLLDIVLALY-SDGCFYRAQIIDEFPSEYMI 644
            .......:  :.:|      .|:.......:|.    |:|.|.| :||.:|||.:..:......:
Zfish   804 LTTDEDEIFSLIEKLNCTLISDLQVELNLLQSD----DLVKAEYPADGAYYRAVVKSKKNGMVQV 864

  Fly   645 FYVDYGN 651
            .::|:||
Zfish   865 QFIDFGN 871

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
krimp	NP_611103.2	TUDOR	568..679	CDD:278965	19/93 (20%)
krimp	NP_611103.2	TUDOR	618..662	CDD:119391	12/35 (34%)
si:ch211-189e2.3	XP_021328732.1	TUDOR	<65..128	CDD:306940
		TUDOR	247..360	CDD:306940	26/126 (21%)
		TUDOR	511..631	CDD:306940	22/136 (16%)
		TUDOR	787..899	CDD:306940	18/89 (20%)
		TUDOR	983..1099	CDD:306940
		TUDOR	1245..1364	CDD:306940
		TUDOR	1453..1572	CDD:306940
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22948
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	1.100