Protein Alignment krimp and tdrkh

DIOPT Version :10

• Sequence 1: NP_611103.2
• Gene: krimp / 36804
• FlyBaseID: FBgn0034098
• Length: 746
• Species: Drosophila melanogaster
• Sequence 2: XP_031747152.1
• Gene: tdrkh / 100145497
• XenbaseID: XB-GENE-5945653
• Length: 720
• Species: Xenopus tropicalis
• Alignment Length: 715
• Identity: 143/715 - (20%)
• Similarity: 245/715 - (34%)
• Gaps: 182/715 - (25%)

  Fly    10 MKLFDSNMHKL---------------QGNLRS---YQTEMHQIHKELTEKLSHADLLYRSLIPLH 56
            :::.|..:::|               :||:|.   .||:.|...||:.:.....::..|..
 Frog    58 LRVLDGEIYELCMKVPSDSVKLLVGKEGNIRKRVRKQTDAHIQVKEVPDSAGAQEVTLRGT---- 118

  Fly    57 DHLVASLSEVNAHVMKLNVQLHINRQ--SVRLGDYEYYEKSIDNPYSSIRSGLQAIEKPGCAEAI 119
            ...|....||...|::.:..|.:..|  |..:|             ..|..|.:.|      .||
 Frog   119 QKQVCHAQEVVNRVLQESAILRVELQLPSKCMG-------------RIIGQGGERI------RAI 164

  Fly   120 CQSSKPAFVECLPSSTSEEV-PVVAVQEASSTNQLDAISVVNENLSEERDATPQPLAVSKNMEET 183
            .::: .|.::|.|.:...:: |...:....:..|::|.....:.:|||..:..|..|
 Frog   165 TRTT-GAKIDCQPRTNGTQMSPTRCITVTGTKEQVEAAKFHIQKVSEEEQSLQQRAA-------- 220

  Fly   184 MPSNPFHEQLEGSLEEIPVGSKIVVETEKANNPVRSEASAPATSDNQSLLAAKQGTQTIGTGICN 248
             .|:.|..:.:   |.|.|..|...|.....:.::.|              .:.|.:.||
 Frog   221 -ESSAFRCRRK---ELISVKKKEAQEANSRGSGIQEE--------------KRGGAEPIG----- 262

  Fly   249 KISKSTINMPNNWQLENPTEVTAASIEKVNKLPK----SPRNRFLLPPKGGTETTRRDIYNQILK 309
                .:::..|....||.|:.|       .::|:    ||...|           |.|.|..:..
 Frog   263 ----ESLHRGNPPSKENVTDTT-------YEVPRFEVSSPEYPF-----------RADEYVDVYV 305

  Fly   310 DMAAFPENTIVTAVLASVDVTDNCAYVAKWDESSDRIKKVLQRQLPLQELDQLPDYGDIFAVLDS 374
            .....||:..: .:|.|.....:.......:...|:...|.:.|:           |||.|....
 Frog   306 SAVENPEHFWI-QILGSRSTQLDKLTSEMTEHYQDKKGGVAEIQV-----------GDIVAAPFR 358

  Fly   375 INNIITRITINSSSAGGGYDAYLIDFGEHIHFD-GNETIFKLPDDIKRLPAQAIRCDLINC---- 434
            .:....|..:......|..|.|.:|:|:  ::| |.|.:|.|..|...||.|||.|.|...
 Frog   359 SDYFWYRAKVAGFLENGNVDLYYVDYGD--NWDVGREKLFPLRHDFLSLPFQAIECGLSKVSPNG 421

  Fly   435 ------------DIANMHCFVNTYIKIRVHENNNSTLVAEPVI--DRLSRPTKTNTTKYPAG--- 482
                        |:.  ||.:...:..::....:..:.:..|:  |..:.|......|..||
 Frog   422 GAWTEEALLYFEDLT--HCALWKPLMAKISSFPSPGVSSFQVLLFDSCTDPVTDIRQKLIAGGFA 484

  Fly   483 -------ITEDD-----MAMLNEIDESTSDPLKAVLGFRPKDEQRICRHYDPKL--NGCFK---- 529
                   :.||:     ..:|:|:...:.:|........|:......|..||.|  :|..:
 Frog   485 VERKESPLREDEEGSLVARLLDEVTSLSLEPETVSFSLEPETVSFSSRLDDPHLPSDGSIELMRA 549

  Fly   530 ----------GNNCRFAHEPFAPNGATKDVELARALPETIFDTTVHFEIGSI-VGILITFI-NGP 582
                      |:..:....|...:.|.::.|  .:|.::|...|:....||: .|...|.. ||.
 Frog   550 DPEPQAAPSLGHKPKVTSTPVCYSRAEEEQE--ESLEKSIAKITLGDSEGSLESGTTETASENGT 612

  Fly   583 TEVYGQFLDGSPPLVWDKKDVPENKRTFKSKPRLLDIVLALYSD-GCFYRAQIIDEFPSEYMIFY 646
            |...|...|.|..|.   ......:.:|.|.| |.|  .::||. ||||  .:.|| |:...|||
 Frog   613 TSYEGSSKDSSVDLT---GSFTSEEHSFSSSP-LED--SSIYSPRGCFY--YLTDE-PTSSSIFY 668

  Fly   647  646
             Frog   669  668

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
krimp	NP_611103.2	TUDOR	576..679	CDD:425754	25/73 (34%)
		Tudor_dTUD-like	618..663	CDD:410450	13/30 (43%)
tdrkh	XP_031747152.1	KH_1	70..130	CDD:459630	12/63 (19%)
		KH-I	138..220	CDD:469614	19/101 (19%)
		Tudor_TDRD2	321..413	CDD:410483	25/104 (24%)