DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7786 and DBP

DIOPT Version :9

Sequence 1:	NP_611101.1	Gene:	CG7786 / 36802	FlyBaseID:	FBgn0034096	Length:	192	Species:	Drosophila melanogaster
Sequence 2:	NP_001343.2	Gene:	DBP / 1628	HGNCID:	2697	Length:	325	Species:	Homo sapiens

Alignment Length:	189	Identity:	61/189 - (32%)
Similarity:	90/189 - (47%)	Gaps:	52/189 - (27%)

- Green bases have known domain annotations that are detailed below.

  Fly     3 SPAQSPILDVTETVSMHSELDAELESKNNPS----YSISI-------PQNLRLTGLGFPGMIGAK 56
            ||..:|......|.|.|.   |.|.|::.||    .::.:       |.:|.|:
Human   165 SPGHAPARAALGTASGHR---AGLTSRDTPSPVDPDTVEVLMTFEPDPADLALS----------- 215

  Fly    57 RSSETLPAFEYIAPPSHALQALEF---PLMELNRVGVIGGGMFPGFVHRRVRGEKRPIPEAQKDA 118
                ::|..|...|..|.....|.   |:|:                    :..|..:||.|||.
Human   216 ----SIPGHETFDPRRHRFSEEELKPQPIMK--------------------KARKIQVPEEQKDE 256

  Fly   119 KYFERRKRNNEAAKRSRDARKIREDRIAFRAALLEQENSILRAQVLALRDELQTVRQLL 177
            ||:.||.:||||||||||||:::|::|:.|||.||:||::||.:|:|:|.||...|.:|
Human   257 KYWSRRYKNNEAAKRSRDARRLKENQISVRAAFLEKENALLRQEVVAVRQELSHYRAVL 315

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7786	NP_611101.1	bZIP_HLF	116..175	CDD:269843	34/58 (59%)
CG7786	NP_611101.1	coiled coil	117..175	CDD:269843	33/57 (58%)
DBP	NP_001343.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..99
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	127..200		11/37 (30%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	229..255		7/45 (16%)
		bZIP_HLF	254..313	CDD:269843	34/58 (59%)
		Basic motif. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	257..279		16/21 (76%)
		coiled coil	258..309	CDD:269843	30/50 (60%)
		Leucine-zipper. /evidence=ECO:0000255\|PROSITE-ProRule:PRU00978	283..297		8/13 (62%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165151881
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3119
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000980
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
User_Submission	0	0.000	Not matched by this tool.
	5	4.700