Protein Alignment Tsf3 and tfa

DIOPT Version :10

• Sequence 1: NP_523759.1
• Gene: Tsf3 / 36800
• FlyBaseID: FBgn0034094
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001278428.1
• Gene: tfa / 30255
• ZFINID: ZDB-GENE-980526-35
• Length: 673
• Species: Danio rerio
• Alignment Length: 733
• Identity: 166/733 - (22%)
• Similarity: 283/733 - (38%)
• Gaps: 149/733 - (20%)

  Fly    16 LSISMCVAVQPPD---DGKLRVCVVESRGVYRKTPKFCPLLEAK-SNIECVIGVDRLDCVRRIHK 76
            :|:..|:.|..|.   ..|::.||..     :.....|..|..| ::|||.:....:||:|.|..
Zfish     6 ISLLGCLVVALPSASAQKKVKWCVTT-----QNEQSKCRHLATKAADIECHLQPTVIDCMRSIAA 65

  Fly    77 GTAHFGVLTSEDLVAARWASV------EILVASELRSHESHFEYEIVAVVDNHANIHTVHDLRGA 135
            |        ..|:|....|:|      ..|:...:...:....|.:.||  ...:...:::|:|.
Zfish    66 G--------GTDIVTVDGANVFTGGLNNYLLRPIIAEKKKECCYAVAAV--KAGSGFNINELKGK 120

  Fly   136 RLCHPGYGLGNHWTEVLANYFEAAMVSKTCDPEMTVTEDRIASTAKYFGPSCKAGPWVPDPKQDR 200
            ..||..|.....|...:........::.....||.|..    :.:::|..||..|
Zfish   121 SSCHSCYQRSGGWNTPIGKLIATNKITWEGPNEMPVER----AVSEFFSSSCVPG---------- 171

  Fly   201 ILKNRYPSLCEMCYEPDSCDQTDKHWGRRGALYCLTSGGGNVAWARLDDVRSHFGFSGIPAQSNP 265
            :.|.:||:||:.|....||...:|::|..||..||.:..|.||:     |..|    .|| :|..
Zfish   172 VSKPKYPNLCKACQGDCSCSHNEKYFGDDGAFQCLKNDNGQVAF-----VCHH----AIP-ESER 226

  Fly   266 SDFSYLCPDGHLQPLNASQPCVWVAKPWPVVAARRSHAAQV------QRLVTGLNHDEPDSWQNA 324
            .::..||.||..:.:...:.|.:..:|...|.||.....|.      |...:.|...:....::.
Zfish   227 QNYELLCMDGSRKSVEDYKTCNFAREPARTVIARTDTDLQYVYDVLKQIPASDLFSSQAFGGKDL 291

  Fly   325 LLSLLETYHVFTVP--LDNVIAI-DDYLDQATAFQSAYSFPECNP--PRS---IVFCTTSIIQHI 381
            :.|...| .:..:|  .|:::.: ::|      :::..:|.:.||  |.|   :..||....:..
Zfish   292 IFSDSAT-ELMLLPKRTDSLLYLKEEY------YEAMQAFKDGNPSAPTSQTKLAMCTIGHAEKN 349

  Fly   382 KCSWLQEASQVYGVQPNIQCVRTMDEQQCLDNTKFKETDVVLVDQEMRVKAQRDYNLVPLLYEFA 446
            ||..|....:        .|:.......|::..|.||.|.:.||.. :|.......|||::.|.:
Zfish   350 KCDSLDHVKK--------SCILEASVDDCIEKIKRKEADFLAVDGG-QVYIAGKCGLVPVMAEQS 405

  Fly   447 ADMH--------DRYVTIALVHKDAKFESFRDLKGARACLPSFEGAAHLSVQETIVNATGKVQSL 503
            ....        ..|..:|:|.|.:.. ::.:|:|.::|......:|...:.|:.:.......:|
Zfish   406 NSQSCSSGSGGTASYYAVAVVRKGSGL-TWNNLEGKKSCHTGLGRSAGWKIPESAICGEKDKCTL 469

  Fly   504 HSYFHR----------DSCLWNLQSGR------KC----PLHYQGDEGALRCLSEGA-DVAFLSS 547
            ..:|..          :.|.....||:      ||    ...|.|.:||.|||:|.| ||||:
Zfish   470 DKFFSEGCAPGADPTSNMCKLCKGSGKPVGDESKCKPSAEEQYYGYDGAFRCLAEKAGDVAFI-- 532

  Fly   548 DVYKKYVVGNLT----SNWLTPGNHKDFRVLCPY--GGIEKRSNFEYCYLHWTTRGHLMTHNSSL 606
               |..|||:.|    .:|......:||.::||.  ....|.::||.|.|.......::|...:
Zfish   533 ---KHTVVGDYTDGKGKDWAKDLKSEDFELICPNTPDTTMKYTDFEKCNLAQVPVHAVITREDA- 593

  Fly   607 TRRNEIYNSLRDM----DQLFGRKYKSETRPFTLYGIFDKRNNVLFRDDTDGLLGLQELHR--DN 665
              |:.:.:.|.|:    :.||..|               ...|:||   |||...|||:..  |:
Zfish   594 --RSAVVSFLSDIQSKNNDLFTSK---------------DGKNLLF---TDGTKCLQEIKGSVDD 638

  Fly   666 --AKRVMEHIYDRYANTQ 681
              .|:.::.|...|..:|
Zfish   639 FLTKKYIDMIERTYKTSQ 656

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	76/352 (22%)
		PBP2_transferrin	369..681	CDD:270247	83/357 (23%)
tfa	NP_001278428.1	Periplasmic_Binding_Protein_Type_2	25..325	CDD:473866	73/345 (21%)
		Periplasmic_Binding_Protein_Type_2	336..648	CDD:473866	80/347 (23%)