Protein Alignment Tsf3 and Ltf

DIOPT Version :10

• Sequence 1: NP_523759.1
• Gene: Tsf3 / 36800
• FlyBaseID: FBgn0034094
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_001100334.1
• Gene: Ltf / 301034
• RGDID: 1305445
• Length: 709
• Species: Rattus norvegicus
• Alignment Length: 780
• Identity: 167/780 - (21%)
• Similarity: 283/780 - (36%)
• Gaps: 212/780 - (27%)

  Fly    15 FLSISMCVAVQPP----DDGKLRVCVVESRGVYRKTPKFCPLLEAKSNIECVIGVDRLDCVRRIH 75
            |:::.|.:.|..|    .|..:|.|.: ||...:|    |.:.:...|   ..||.:|.|.|:
  Rat     4 FITVLMFLGVLGPFLARIDTVVRWCTI-SRNEAQK----CFMWQEMLN---KAGVPKLRCARK-- 58

  Fly    76 KGTAHFGVLTSEDLVAARWASVEIL---------------VASEL--RSHESHFEYEIVAVVDNH 123
                :|.....::::..|..::.:.               :|:|:  ...:....|..||||.|.
  Rat    59 ----YFMPHCIQEIMMRRADAMTLSGSAIFDFYFPYKLQPIAAEVYGTKEKPRIHYYAVAVVKNS 119

  Fly   124 ANIHTVHDLRGARLCHPGYGLGNHWTEVLANYFEAAMVSKTCDPEMTVTEDRIA---STAKYFGP 185
            ::|. ::.|:|.:.||.|:.....|...|.          ...|.:...|..::   :.:|:|..
  Rat   120 SDIR-LNQLQGLKSCHAGFDTSAGWIAPLG----------ALRPYLNWDEKSVSLEEAVSKFFSQ 173

  Fly   186 SCKAGPWVPDPKQDRILKNRYPSLCEMCYEPDS--CD--QTDKHWGRRGALYCLTSGGGNVAWAR 246
            ||..|          |.|:|:|.||.:|.....  ||  ..:.:.|..||..||....|:||:.|
  Rat   174 SCVPG----------ISKSRFPRLCSLCAGKGEHICDFSPQEPYAGYAGAFRCLRDNAGDVAFIR 228

  Fly   247 LDDVRSHFGFSGIPAQSNPSDFSYLCPDGHLQPLNASQPCVWVAKPWPVVAARRSHAAQV-QRLV 310
            ...:     |..:|.::....:..||||...:|:...:.|               |.||: .|.|
  Rat   229 ESTI-----FEELPNEAEWDQYKLLCPDNTWKPVTEYKEC---------------HLAQIPSRAV 273

  Fly   311 TGLNHDEPDS--WQNALLSLLE---------TYHVFTVPL--------DNVI-------AIDDYL 349
            ......|.||  |:  ||.|.:         .:.:|...|        |:||       .::.:|
  Rat   274 VAHVRSEKDSAIWE--LLHLSQEMFGKNKTSKFELFGSYLGQKDLLFKDSVIGFVRVPFTVNVWL 336

  Fly   350 DQATAFQSAY-SFPECNP-----PRSIVFCTTSIIQHIKCSWLQEASQVYGVQPNIQCVRTMDEQ 408
            ....::..|. |..|...     ...|.:|.....:.:||......|     ...|.|:.....:
  Rat   337 YLTFSYIMALKSLKESKENVMALRARITWCAVGSEEKLKCDQWSRVS-----VGKITCISCTTTE 396

  Fly   409 QCLDNTKFKETDVVLVDQEMRVKAQRDYNLVPLLYEF-------AADMHDR----YVTIALVHKD 462
            ||:.:....:.|.:.:|......|.: ..|||:|.|.       .:|..||    |:.:|.|.|:
  Rat   397 QCIFSITMGDADAMNLDGGYIYSAGK-CGLVPVLAEIQKSPNSNGSDCVDRPAEGYLAVAAVRKE 460

  Fly   463 AKFESFRDLKGARACLPSFEGAAHLSVQET---------IVNATGKVQSLHSYFHRDS------- 511
            ....::..::|.::|        |.:|..|         :||.|...| ...:|::..
  Rat   461 DTGFTWSTVRGKKSC--------HTAVDRTAGWNIPMGLLVNQTNSCQ-FKEFFNKSCAPGSFLY 516

  Fly   512 ------CLWNLQSGRKC----PLHYQGDEGALRCLSEGA-DVAFLSSDVYKKYVVGNLTSNWLTP 565
                  |:.:.....||    ...|||..||.|||:|.| :||||......:...|.....|...
  Rat   517 SNLCALCIGDENGKDKCNPNSQERYQGYVGAFRCLAEKAGNVAFLKDATVLQNTDGKNADKWAKN 581

  Fly   566 GNHKDFRVLCPYGGIEKRSNFEYCYLHWTTRGHLMT---HNSSLTRRNEIYNSLRDMDQLFGRK- 626
            ....||.:||.....:..:..:.|:|. ....|.:.   ..:.|.::..:|..::     |||.
  Rat   582 LKLDDFELLCLDDTRKPVTEAKNCHLA-VAPNHAVVARKDKARLVQQELLYQQVQ-----FGRNG 640

  Fly   627 ---------YKSETRPFTLYGIFDKRNNVLFRDDTDGLLGLQELHRDNAKRVMEHIYDRYANTQY 682
                     ::|||:            |:||.|:|:.|          ||...:..::.|...:|
  Rat   641 CRCPEEFCLFRSETK------------NLLFNDNTECL----------AKLPSKITWEEYLGKEY 683

  Fly   683  682
              Rat   684  683

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	84/391 (21%)
		PBP2_transferrin	369..681	CDD:270247	77/362 (21%)
Ltf	NP_001100334.1	Transferrin	25..351	CDD:395328	83/382 (22%)
		PBP2_transferrin_C	360..691	CDD:270335	78/367 (21%)