Protein Alignment Tsf3 and Trf

DIOPT Version :10

• Sequence 1: NP_523759.1
• Gene: Tsf3 / 36800
• FlyBaseID: FBgn0034094
• Length: 714
• Species: Drosophila melanogaster
• Sequence 2: NP_598738.1
• Gene: Trf / 22041
• MGIID: 98821
• Length: 697
• Species: Mus musculus
• Alignment Length: 807
• Identity: 176/807 - (21%)
• Similarity: 288/807 - (35%)
• Gaps: 226/807 - (28%)

  Fly     7 ILVGLFASFLSISMCVAVQPPDDGKLRVCVVESRGVYRKTPKFCPLLEAKSNIECVIGVD----- 66
            :.||...:..::.:|:||  ||                ||.|:|.:.| ..|.:|:...|
Mouse     3 LTVGALLACAALGLCLAV--PD----------------KTVKWCAVSE-HENTKCISFRDHMKTV 48

  Fly    67 ------RLDCVRR-------------------IHKGTAHFGVLTSEDL--VAAR-WASVEILVAS 103
                  ||.||::                   :..|..:...||..:|  |||. :.|||
Mouse    49 LPPDGPRLACVKKTSYPDCIKAISASEADAMTLDGGWVYDAGLTPNNLKPVAAEFYGSVE----- 108

  Fly   104 ELRSHESHFEYEIVAVVDNHANIHTVHDLRGARLCHPGYGLGNHWTEVLANYFEAAMVSKTCDPE 168
                |...: |..||||....:.. ::.|.|.:.||.|.|....|...:...|     .|..:|.
Mouse   109 ----HPQTY-YYAVAVVKKGTDFQ-LNQLEGKKSCHTGLGRSAGWVIPIGLLF-----CKLSEPR 162

  Fly   169 MTVTEDRIASTAKYFGPSCKAGPWVP--DPKQDRILKNRYPSLCEMCYEPD-SCDQTDKHWGRRG 230
            ..:.:    :.:.:|..||     ||  ||.       .:|.||::|  |. .|..|...:|..|
Mouse   163 SPLEK----AVSSFFSGSC-----VPCADPV-------AFPKLCQLC--PGCGCSSTQPFFGYVG 209

  Fly   231 ALYCLTSGGGNVAWARLDDVRSHFGFSGIPAQSNPSDFSYLCPDGHLQPLNASQPCVWVAKPWPV 295
            |..||..|||:||:.:...:     |..:|.:::...:..||.|...:|::..:.|.....|...
Mouse   210 AFKCLKDGGGDVAFVKHTTI-----FEVLPEKADRDQYELLCLDNTRKPVDQYEDCYLARIPSHA 269

  Fly   296 VAARRSHAAQVQRLVTGLNHDEPDSWQNALLSLLE---------TYHVFTVPLDNVIAIDD---- 347
            |.||::            |..|...|:  :|.:.:         .:.:|:.||...:...|
Mouse   270 VVARKN------------NGKEDLIWE--ILKVAQEHFGKGKSKDFQLFSSPLGKDLLFKDSAFG 320

  Fly   348 ------------YL--DQATAFQSAYS--FPECNPPRS-IVFCTTSIIQHIKC-SW--LQEASQV 392
                        ||  :..||.::...  .||.:...| :.:|..|.::..|| .|  :.|.
Mouse   321 LLRVPPRMDYRLYLGHNYVTAIRNQQEGVCPEGSIDNSPVKWCALSHLERTKCDEWSIISEG--- 382

  Fly   393 YGVQPNIQCVRTMDEQQCLDNTKFKETDVVLVDQEMRVKAQRDYNLVPLLYEFAADMH------- 450
                 .|:|......:.|::.....|.|.:.:|......|.: ..|||::.|:....:
Mouse   383 -----KIECESAETTEDCIEKIVNGEADAMTLDGGHAYIAGQ-CGLVPVMAEYYESSNCAIPSQQ 441

  Fly   451 ----DRYVTIALVHKDAKFESFRDLKGARACLPSFEGAAHLSVQET---------IVNATG--KV 500
                ..|..:|:|.......::.:|||.::|        |..|..|         :.|...  |.
Mouse   442 GIFPKGYYAVAVVKASDTSITWNNLKGKKSC--------HTGVDRTAGWNIPMGMLYNRINHCKF 498

  Fly   501 QSLHSY-----FHRDSCLWNLQSG-RKCPLH----YQGDEGALRCLSEGADVAFLSSDVYKKYVV 555
            ....|.     :.::|.|.:|..| .||..:    |.|..||.|||.|..||||:..........
Mouse   499 DEFFSQGCAPGYEKNSTLCDLCIGPLKCAPNNKEEYNGYTGAFRCLVEKGDVAFVKHQTVLDNTE 563

  Fly   556 GNLTSNWLTPGNHKDFRVLCPYGGIEKRSNFEYCYLHWTTRGHLMTHNSSLTRRNEIYNSLRDMD 620
            |...:.|......:||.:|||.|..:...:|..|:|.......:::......|...:   |...:
Mouse   564 GKNPAEWAKNLKQEDFELLCPDGTRKPVKDFASCHLAQAPNHVVVSRKEKAARVKAV---LTSQE 625

  Fly   621 QLFGRK--------YKSETRPFTLYGIFDKRNNVLFRDDTDGLLGLQELHRDNAKRVMEHIYDRY 677
            .|||..        :||.|:            ::||||||...:.|.|          ....::|
Mouse   626 TLFGGSDCTGNFCLFKSTTK------------DLLFRDDTKCFVKLPE----------GTTPEKY 668

  Fly   678 ANTQYYRNFDESGAMKSSHNLWILLVC 704
            ...:|.::.   |.|:......:|..|
Mouse   669 LGAEYMQSV---GNMRKCSTSRLLEAC 692

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tsf3	NP_523759.1	PBP2_transferrin	33..368	CDD:270247	87/399 (22%)
		PBP2_transferrin	369..681	CDD:270247	77/355 (22%)
Trf	NP_598738.1	PBP2_transferrin_N	24..344	CDD:270336	84/373 (23%)
		PBP2_transferrin_C	359..681	CDD:270335	78/366 (21%)