Protein Alignment ITGA9 and Itga9

DIOPT Version :10

• Sequence 1: NP_002198.2
• Gene: ITGA9 / 3680
• HGNCID: 6145
• Length: 1035
• Species: Homo sapiens
• Sequence 2: NP_001406931.1
• Gene: Itga9 / 685004
• RGDID: 1311191
• Length: 1036
• Species: Rattus norvegicus
• Alignment Length: 1036
• Identity: 934/1036 - (90%)
• Similarity: 980/1036 - (94%)
• Gaps: 1/1036 - (0%)

Human     1 MGGPAAP-RGAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVL 64
            ||||||. .|||.|||||||||.||:||||||:|.||||.||||..|||||||||||||||||||
  Rat     1 MGGPAAKGTGAGGLRALLLALVAAGVPAGAYNIDAQRPVRFQGPPGSFFGYAVLEHFHDNTRWVL 65

Human    65 VGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSL 129
            |||||||||||.||||||||||||||||||||||||||||.:|||.|||||||.|||||||||||
  Rat    66 VGAPKADSKYSTSVKSPGAVFKCRVHTNPDRRCTELDMARERNRGESCGKTCRGDRDDEWMGVSL 130

Human   130 ARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCYEEYKKKYGEEHGSC 194
            |||||||||||||||||||||||.||||||||||:||||||||||.|||||||||||||||||||
  Rat   131 ARQPKADGRVLACAHRWKNIYYETDHILPHGFCYLIPSNLQAKGRMLIPCYEEYKKKYGEEHGSC 195

Human   195 QAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGYAVTAGHFSHP 259
            |||||||||||||:||||||||||||:||||||||||.||||:.|||||||||||||||||||||
  Rat   196 QAGIAGFFTEELVIMGAPGSFYWAGTLKVLNLTDNTYFKLNDDAIMNRRYTYLGYAVTAGHFSHP 260

Human   260 STIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVG 324
            |..|||||||||:||||||||||||||||||||||||||||||||||||||||||.|||||||||
  Rat   261 SVTDVVGGAPQDEGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNMDGLSDLLVG 325

Human   325 APMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE 389
            ||||||||||||||||:|:|:|.|||||.||||.|||||||||||||.|||:|||||||:|||.|
  Rat   326 APMFSEIRDEGQVTVYLNQGHGVLEEQLTLTGDAAYNAHFGESIASLGDLDDDGFPDVAVGAPME 390

Human   390 DDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSV 454
            |||||.||||||||.||||||||||||:||||:|:|||||||||||||||||||||||||:||||
  Rat   391 DDFAGTVYIYHGDAQGIVPQYSMKLSGRKINPILQMFGQSISGGIDMDGNGYPDVTVGAFLSDSV 455

Human   455 VLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADV 519
            |||||||||||||||||||||||||||||||||||||||||.||.||||:|||||||||.|.|||
  Rat   456 VLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTVCFRFHGKNVPGEIGLNYNLTADV 520

Human   520 AKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEH 584
            |:|||||:|||||||||||.|||:|:||||:|:|.|.|||||||||||||||||||||||||.||
  Rat   521 AQKEKGQLPRVYFVLLGETAGQVSERLQLTHMDEVCHHYVAHVKRRVQDVISPIVFEAAYSLGEH 585

Human   585 VTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLAL 649
            |.|||:||||.|||||||||||:||||||||||||||||||||||||:|||||||:||||.:|||
  Rat   586 VIGEEDRELPDLTPVLRWKKGQRIAQKNQTVFERNCRSEDCAADLQLRGKLLLSSVDEKTTHLAL 650

Human   650 GAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMR 714
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   651 GAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMR 715

Human   715 SKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSP 779
            |||||||||||||||||||||:|||||||||||.||||:||||||.|.:||:||||||||||:||
  Rat   716 SKSKYEFSVIFDTSHLSGEEEILSFIVTAQSGNMERSEALHDNTLTLTIPLVHEVDTSITGIVSP 780

Human   780 TSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQ 844
            |||||||||||:|||||||.||||||:||||||||.|||||||||||||||:|||.||||||.||
  Rat   781 TSFVYGESVDASNFIQLDDQECHFQPVNITLQVYNMGPSTLPGSSVSISFPSRLSPGGAEMFQVQ 845

Human   845 EMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALA 909
            :|||.|||||||.|:||||||||||||||||||||||:|||||||||||.|..|||.|||.|||.
  Rat   846 DMVVSQEKGNCSLQRNPTPCIIPQEQENIFHTIFAFFSKSGRKVLDCEKTGSFCLTLHCNLSALP 910

Human   910 KEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEP 974
            |||||.||:||||||||||||||||||||:||||||:|||||||||:|||||..|||||||||||
  Rat   911 KEESRAIDLYMLLNTEILKKDSSSVIQFMARAKVKVEPALRVVEIANGNPEETLVVFEALHNLEP 975

Human   975 RGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDSWDWVQKNQ 1035
            |||||||||||||||||||||||||||||||||||||||||||||||||||::||||||||
  Rat   976 RGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEEAWDWVQKNQ 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ITGA9	NP_002198.2	FG-GAP 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	35..96		56/60 (93%)
		Int_alpha	44..101	CDD:214549	53/56 (95%)
		FG-GAP 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	111..174		59/62 (95%)
		FG-GAP 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	182..232		47/49 (96%)
		FG-GAP 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	233..289		50/55 (91%)
		Int_alpha	244..294	CDD:214549	46/49 (94%)
		FG-GAP 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	290..349		53/58 (91%)
		Int_alpha	300..347	CDD:214549	42/46 (91%)
		FG-GAP 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	351..408		48/56 (86%)
		Int_alpha	361..414	CDD:214549	46/52 (88%)
		FG-GAP 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	411..474		58/62 (94%)
		Int_alpha	425..>466	CDD:214549	39/40 (98%)
		Integrin_alpha2	460..903	CDD:462478	395/442 (89%)
		GFFKR motif	1005..1009		3/3 (100%)
Itga9	NP_001406931.1	Int_alpha	45..102	CDD:214549	53/56 (95%)
		Int_alpha	245..295	CDD:214549	46/49 (94%)
		Int_alpha	301..347	CDD:214549	42/45 (93%)
		Int_alpha	362..415	CDD:214549	46/52 (88%)
		Int_alpha	425..>467	CDD:214549	39/41 (95%)
		Integrin_alpha2	461..904	CDD:462478	395/442 (89%)