Protein Alignment ITGA9 and Itga9

DIOPT Version :10

• Sequence 1: NP_002198.2
• Gene: ITGA9 / 3680
• HGNCID: 6145
• Length: 1035
• Species: Homo sapiens
• Sequence 2: NP_598482.2
• Gene: Itga9 / 104099
• MGIID: 104756
• Length: 1036
• Species: Mus musculus
• Alignment Length: 1036
• Identity: 932/1036 - (89%)
• Similarity: 984/1036 - (94%)
• Gaps: 1/1036 - (0%)

Human     1 MGGPAAPR-GAGRLRALLLALVVAGIPAGAYNLDPQRPVHFQGPADSFFGYAVLEHFHDNTRWVL 64
            ||||||.| |||.|||||||||.||:||||||||.||||.||||:.|||||||||||||||||||
Mouse     1 MGGPAAARTGAGGLRALLLALVAAGVPAGAYNLDAQRPVRFQGPSGSFFGYAVLEHFHDNTRWVL 65

Human    65 VGAPKADSKYSPSVKSPGAVFKCRVHTNPDRRCTELDMARGKNRGTSCGKTCREDRDDEWMGVSL 129
            |||||||||||.|||||||||||||||||||||||||||||:.||..||||||.|||||||||||
Mouse    66 VGAPKADSKYSTSVKSPGAVFKCRVHTNPDRRCTELDMARGRTRGAPCGKTCRGDRDDEWMGVSL 130

Human   130 ARQPKADGRVLACAHRWKNIYYEADHILPHGFCYIIPSNLQAKGRTLIPCYEEYKKKYGEEHGSC 194
            ||||:|||||||||||||||||||||||||||||:|||||||||:.|||||||||||||||||||
Mouse   131 ARQPRADGRVLACAHRWKNIYYEADHILPHGFCYLIPSNLQAKGKVLIPCYEEYKKKYGEEHGSC 195

Human   195 QAGIAGFFTEELVVMGAPGSFYWAGTIKVLNLTDNTYLKLNDEVIMNRRYTYLGYAVTAGHFSHP 259
            ||||||||||||||||||||||||||:||||||||||.|||||.|||||||||||||||||||||
Mouse   196 QAGIAGFFTEELVVMGAPGSFYWAGTLKVLNLTDNTYFKLNDEAIMNRRYTYLGYAVTAGHFSHP 260

Human   260 STIDVVGGAPQDKGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNGDGLSDLLVG 324
            |..|||||||||:||||||||||||||||||||||||||||||||||||||||||.|||||||||
Mouse   261 SITDVVGGAPQDEGIGKVYIFRADRRSGTLIKIFQASGKKMGSYFGSSLCAVDLNMDGLSDLLVG 325

Human   325 APMFSEIRDEGQVTVYINRGNGALEEQLALTGDGAYNAHFGESIASLDDLDNDGFPDVAIGAPKE 389
            ||||||||||||||||:|:|:|||||||.||||.|||||||||||:|.|:|:|||||||:|||||
Mouse   326 APMFSEIRDEGQVTVYLNQGHGALEEQLTLTGDAAYNAHFGESIANLGDIDDDGFPDVAVGAPKE 390

Human   390 DDFAGAVYIYHGDAGGIVPQYSMKLSGQKINPVLRMFGQSISGGIDMDGNGYPDVTVGAFMSDSV 454
            :|||||||||||||.||||:|||||||:::||.|||||||||||||||||||||||:|||:||||
Mouse   391 EDFAGAVYIYHGDANGIVPKYSMKLSGRRLNPTLRMFGQSISGGIDMDGNGYPDVTIGAFLSDSV 455

Human   455 VLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTTCFSFHGKHVPGEIGLNYVLMADV 519
            |||||||||||||||||||||||||||||||||||||||||.||.||||:|||||||||.|.|||
Mouse   456 VLLRARPVITVDVSIFLPGSINITAPQCHDGQQPVNCLNVTVCFRFHGKNVPGEIGLNYNLTADV 520

Human   520 AKKEKGQMPRVYFVLLGETMGQVTEKLQLTYMEETCRHYVAHVKRRVQDVISPIVFEAAYSLSEH 584
            |:|||||:|||||||.|||.|||:|:|||::|:|.|.|||||||||||||||||||||||||.||
Mouse   521 AQKEKGQLPRVYFVLFGETAGQVSERLQLSHMDEVCHHYVAHVKRRVQDVISPIVFEAAYSLDEH 585

Human   585 VTGEEERELPPLTPVLRWKKGQKIAQKNQTVFERNCRSEDCAADLQLQGKLLLSSMDEKTLYLAL 649
            |.|||:||||.|||||||||||:|:|||||||||||:||||||||||:|||||||:||||.:|||
Mouse   586 VMGEEDRELPDLTPVLRWKKGQRISQKNQTVFERNCQSEDCAADLQLRGKLLLSSVDEKTPHLAL 650

Human   650 GAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMR 714
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   651 GAVKNISLNISISNLGDDAYDANVSFNVSRELFFINMWQKEEMGISCELLESDFLKCSVGFPFMR 715

Human   715 SKSKYEFSVIFDTSHLSGEEEVLSFIVTAQSGNTERSESLHDNTLVLMVPLMHEVDTSITGIMSP 779
            |||||||||||||||||||||:|||||||||||.||||:||||||.|.|||:||||||||||:||
Mouse   716 SKSKYEFSVIFDTSHLSGEEEILSFIVTAQSGNLERSEALHDNTLTLTVPLVHEVDTSITGIVSP 780

Human   780 TSFVYGESVDAANFIQLDDLECHFQPINITLQVYNTGPSTLPGSSVSISFPNRLSSGGAEMFHVQ 844
            |||||||||||:|||||||.||||||:||||||||.|||||||||||||||:|||.||||||.||
Mouse   781 TSFVYGESVDASNFIQLDDQECHFQPVNITLQVYNMGPSTLPGSSVSISFPSRLSPGGAEMFQVQ 845

Human   845 EMVVGQEKGNCSFQKNPTPCIIPQEQENIFHTIFAFFTKSGRKVLDCEKPGISCLTAHCNFSALA 909
            :|||.|||||||.|:||||||||||||||||||||||:|||||||||||||..|||.|||.|||.
Mouse   846 DMVVSQEKGNCSLQRNPTPCIIPQEQENIFHTIFAFFSKSGRKVLDCEKPGSFCLTLHCNLSALP 910

Human   910 KEESRTIDIYMLLNTEILKKDSSSVIQFMSRAKVKVDPALRVVEIAHGNPEEVTVVFEALHNLEP 974
            |||||||::||||||||||||||||||||:||||||:|||||||||:|||||..|||||||||||
Mouse   911 KEESRTINLYMLLNTEILKKDSSSVIQFMARAKVKVEPALRVVEIANGNPEETLVVFEALHNLEP 975

Human   975 RGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDSWDWVQKNQ 1035
            ||||||||||||||||||||||||||||||||||||||||||||||||||||.||||||||
Mouse   976 RGYVVGWIIAISLLVGILIFLLLAVLLWKMGFFRRRYKEIIEAEKNRKENEDGWDWVQKNQ 1036

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ITGA9	NP_002198.2	FG-GAP 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	35..96		56/60 (93%)
		Int_alpha	44..101	CDD:214549	53/56 (95%)
		FG-GAP 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	111..174		58/62 (94%)
		FG-GAP 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	182..232		48/49 (98%)
		FG-GAP 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	233..289		51/55 (93%)
		Int_alpha	244..294	CDD:214549	46/49 (94%)
		FG-GAP 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	290..349		54/58 (93%)
		Int_alpha	300..347	CDD:214549	42/46 (91%)
		FG-GAP 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	351..408		47/56 (84%)
		Int_alpha	361..414	CDD:214549	44/52 (85%)
		FG-GAP 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	411..474		56/62 (90%)
		Int_alpha	425..>466	CDD:214549	38/40 (95%)
		Integrin_alpha2	460..903	CDD:462478	393/442 (89%)
		GFFKR motif	1005..1009		3/3 (100%)
Itga9	NP_598482.2	FG-GAP 1. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	36..97		56/60 (93%)
		Int_alpha	45..102	CDD:214549	53/56 (95%)
		FG-GAP 2. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	109..175		60/65 (92%)
		FG-GAP 3. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	183..233		48/49 (98%)
		FG-GAP 4. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	234..290		51/55 (93%)
		Int_alpha	245..295	CDD:214549	46/49 (94%)
		FG-GAP 5. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	291..350		54/58 (93%)
		Int_alpha	301..348	CDD:214549	42/46 (91%)
		FG-GAP 6. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	352..409		47/56 (84%)
		Int_alpha	362..415	CDD:214549	44/52 (85%)
		FG-GAP 7. /evidence=ECO:0000255|PROSITE-ProRule:PRU00803	412..475		56/62 (90%)
		Int_alpha	426..>467	CDD:214549	38/40 (95%)
		Integrin_alpha2	461..904	CDD:462478	393/442 (89%)
		GFFKR motif. /evidence=ECO:0000250|UniProtKB:Q13797	1006..1010		3/3 (100%)